Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Heiner K Berthold"'
Autor:
Heiner K Berthold, Manfredi Rizzo, Nadine Spenrath, Giuseppe Montalto, Wilhelm Krone, Ioanna Gouni-Berthold
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91565 (2014)
Investigating the effects of lipid-lowering drugs on HDL subclasses has shown ambiguous results. This study assessed the effects of ezetimibe, simvastatin, and their combination on HDL subclass distribution.A single-center randomized parallel 3-group
Externí odkaz:
https://doaj.org/article/1a4a7a5f2c87455282116699c1da2d1b
Autor:
Ioanna Gouni-Berthold, Heiner K Berthold, Joo Young Huh, Reena Berman, Nadine Spenrath, Wilhelm Krone, Christos S Mantzoros
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72858 (2013)
The myokine irisin has been proposed to regulate energy homeostasis. Little is known about its association with metabolic parameters and especially with parameters influencing pathways of lipid metabolism. In the context of a clinical trial, an explo
Externí odkaz:
https://doaj.org/article/69561945173e43b7acdda13891306f78
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60095 (2013)
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a secreted inhibitor of the low-density lipoprotein (LDL) receptor and an important regulator of LDL metabolism. Elevated PCSK9 levels have been associated with cardiovascular risk. The purpose
Externí odkaz:
https://doaj.org/article/08aa8bed04584c339044572b353b279c
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24719 (2011)
BACKGROUND: Lipoprotein(a) [Lp(a)] is an independent risk factor for cardiovascular disease. The interleukin-6 (IL-6) receptor antagonist tocilizumab has been shown to lower serum Lp(a) concentrations. We investigated whether the IL-6 single nucleoti
Externí odkaz:
https://doaj.org/article/9d312d5f7b334a42b0fa31e0c39abe14
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 913 (2024)
Lipid-lowering therapy (LLT) is a cornerstone of atherosclerotic cardiovascular disease prevention. Although LLT might lead to different reductions in low-density lipoprotein cholesterol (LDL-C) levels in women and men, LLT diminishes cardiovascular
Externí odkaz:
https://doaj.org/article/6f48164bd7a84a4c8948801d33ffca72
Autor:
Eberhard Windler, Frank-Ulrich Beil, Heiner K. Berthold, Ioanna Gouni-Berthold, Ursula Kassner, Gerald Klose, Stefan Lorkowski, Winfried März, Klaus G. Parhofer, Jogchum Plat, Günter Silbernagel, Elisabeth Steinhagen-Thiessen, Oliver Weingärtner, Birgit-Christiane Zyriax, Dieter Lütjohann
Publikováno v:
Nutrients
Volume 15
Issue 4
Pages: 828
Nutrients, 15(4):828. Multidisciplinary Digital Publishing Institute (MDPI)
Volume 15
Issue 4
Pages: 828
Nutrients, 15(4):828. Multidisciplinary Digital Publishing Institute (MDPI)
Phytosterols (PSs) have been proposed as dietary means to lower plasma LDL-C. However, concerns are raised that PSs may exert atherogenic effects, which would offset this benefit. Phytosterolemia was thought to mimic increased plasma PSs observed aft
Autor:
Ilaria Campesi, Mark L. Heiman, Heiner K. Berthold, Vera Regitz-Zagrosek, Anne Z. Murphy, Santosh Dakal, Ioanna Gouni-Berthold, Franck Mauvais-Jarvis, Karen Reue, Flavia Franconi, Juan Jesus Carrero, Joshua B. Rubin, Sabra L. Klein, Alexandra Kautzky-Willer
Publikováno v:
Pharmacological Reviews. 73:730-762
In humans, the combination of all sex-specific genetic, epigenetic, and hormonal influences of biologic sex produces different in vivo environments for male and female cells. We dissect how these influences of sex modify the pharmacokinetics and phar
Publikováno v:
Current atherosclerosis reports. 24(10)
Purpose of Review To report on recent data about PCSK9 monoclonal antibodies and to evaluate their relevance in a nucleic acid–based therapy era for lipid lowering and prevention of cardiovascular disease. Recent Findings New methods of PCSK9 inhib
Autor:
Armin Zittermann, Heiner K. Berthold, Jana B. Ernst, Jan Gummert, Sylvana Prokop, Stefan Pilz, Uwe Fuchs, Ioanna Gouni-Berthold
Publikováno v:
ESC Heart Failure
ESC Heart Failure, Vol 7, Iss 6, Pp 3754-3761 (2020)
ESC Heart Failure, Vol 7, Iss 6, Pp 3754-3761 (2020)
Aims Vitamin D supplementation is widely used in the clinical setting, but its effects on mortality and cardiovascular outcomes in patients with heart failure are unclear. This paper reports outcome data that were collected during follow‐up of 3 ye
Publikováno v:
European Journal of Clinical Nutrition
The phosphaturic hormone fibroblast growth factor 23 (FGF23) is a risk marker of cardiovascular and all-cause mortality. We therefore aimed to synthesize the evidence for the effect of vitamin D administration on circulating FGF23 concentrations. We