Tacrolimus Concentration/Dose Ratio is Associated with Renal Function After Liver Transplantation

Autor: Gerold, Thölking, Lea, Siats, Christian, Fortmann, Raphael, Koch, Anna, Hüsing, Vito R, Cicinnati, Hans Ulrich, Gerth, Heiner H, Wolters, Christoph, Anthoni, Hermann, Pavenstädt, Barbara, Suwelack, Hartmut H, Schmidt, Iyad, Kabar

Publikováno v: Annals of transplantation. 21

The calcineurin inhibitor (CNI) tacrolimus (Tac) is an effective immunosuppressant used after liver transplantation (LTx), but is often associated with CNI nephrotoxicity. Currently, there is no simple clinical predictor for CNI nephrotoxicity after

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f86a425386aef33714fd503fab24bb76
https://pubmed.ncbi.nlm.nih.gov/27003330

Acute antibody-mediated rejection in paediatric renal transplant recipients

Autor: Verena Bröcker, Eberhard Kuwertz-Bröking, Reinhard Kelsch, Martin Konrad, Birgitta Kranz, Heiner H. Wolters

Publikováno v: Pediatric nephrology (Berlin, Germany). 26(7)

Acute antibody-mediated rejections (aAMR) after renal transplantation are defined by rapidly deteriorating graft function, detection of donor-specific antibodies (DSA) and characteristic histological features. In adults, anti-rejection strategies com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec7b74466acf16ea75fcbda8ab239b8
https://pubmed.ncbi.nlm.nih.gov/21461632

Lasting response by vertical inhibition with cetuximab and trametinib in KRAS-mutated colorectal cancer patient-derived xenografts.

Autor: Reissig TM; Department of Molecular GI Oncology, Faculty of Medicine, Ruhr-University Bochum, Germany.; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Germany.; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Germany., Ladigan-Badura S; Department of Molecular GI Oncology, Faculty of Medicine, Ruhr-University Bochum, Germany.; Center for Hemato-Oncological Diseases, University Hospital Knappschaftskrankenhaus, Ruhr-University Bochum, Germany., Steinberg A; Department of Molecular GI Oncology, Faculty of Medicine, Ruhr-University Bochum, Germany., Maghnouj A; Department of Molecular GI Oncology, Faculty of Medicine, Ruhr-University Bochum, Germany., Li T; Department of Molecular GI Oncology, Faculty of Medicine, Ruhr-University Bochum, Germany., Verdoodt B; Institute of Pathology, Ruhr University Bochum, Germany., Liffers ST; Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Germany.; Institute of Pathology, Ruhr University Bochum, Germany., Pohl M; Center for Hemato-Oncological Diseases, University Hospital Knappschaftskrankenhaus, Ruhr-University Bochum, Germany., Wolters H; Department of Visceral and General Surgery, St. Josef Hospital, Dortmund, Germany., Teschendorf C; Department of Visceral and General Surgery, St. Josef Hospital, Dortmund, Germany., Viebahn R; Department of Visceral and General Surgery, University Hospital Knappschaftskrankenhaus, Ruhr-University Bochum, Germany., Admard J; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Germany., Casadei N; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Germany., Tannapfel A; Institute of Pathology, Ruhr University Bochum, Germany., Schmiegel W; Center for Hemato-Oncological Diseases, University Hospital Knappschaftskrankenhaus, Ruhr-University Bochum, Germany., Hahn SA; Department of Molecular GI Oncology, Faculty of Medicine, Ruhr-University Bochum, Germany., Vangala DB; Department of Molecular GI Oncology, Faculty of Medicine, Ruhr-University Bochum, Germany.; Center for Hemato-Oncological Diseases, University Hospital Knappschaftskrankenhaus, Ruhr-University Bochum, Germany.

Publikováno v: Molecular oncology [Mol Oncol] 2023 Nov; Vol. 17 (11), pp. 2396-2414. Date of Electronic Publication: 2023 Sep 03.

Impact of adjuvant therapy in patients with invasive intraductal papillary mucinous neoplasms of the pancreas: an international multicenter cohort study.

Autor: Choi M; Department of Surgery, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin-si, Korea., Wang SE; Department of Surgery, Taipei Veterans General Hospital, National Yang Ming University, Taipei, Taiwan., Park JS; Department of Surgery, Gangnam Severance Hospital., Kim HS; Department of Surgery, Gangnam Severance Hospital., Choi SH; Department of Surgery, CHA Bundang Medical Center, CHA University, Seongam-si, Korea., Lee JH; Department of Surgery, National Health Insurance Service Ilsan Hospital, Goyang, Korea., Chong JU; Department of Surgery, National Health Insurance Service Ilsan Hospital, Goyang, Korea., Nagakawa Y; Department of Gastrointestinal and Pediatric Surgery, Tokyo Medical University, Tokyo, Japan., Wada K; Department of Surgery, Teikyo University School of Medicine, Tokyo, Japan., Nakamura Y; Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, Tokyo, Japan., Sunagawa H; Department of Gastrointestinal Surgery, Nakagami Hospital, Okinawa, Japan., Dasari BV; Department of HPB and Liver Transplantation, Queen Elizabeth Hospital, Birmingham, UK., Peng CM; Department of General Surgery, Chung Shan Medical University Hospital, Taichung, Taiwan., Seng LL; Hepatopancreatobiliary Unit, Department of General Surgery, Changi General Hospital, Singapore., Wolters H; Department of Visceral and General Surgery, St. Josefs-Hospital, Dortmund, Germany., Gurbadam U; Department of Surgery, National Cancer Center Hospital, Ulan Bator, Mongolia., Park BU; Department of Pathology, The University of California, San Francisco, CA., Winslow E; Department of Pathology, The University of California, San Francisco, CA.; MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC, USA., Fishbein T; MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC, USA., Hawksworth J; MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC, USA., Radkani P; MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC, USA., Kang CM; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Publikováno v: International journal of surgery (London, England) [Int J Surg] 2023 Oct 01; Vol. 109 (10), pp. 2906-2913. Date of Electronic Publication: 2023 Oct 01.

Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma.

Autor: Heid I; Institute of Diagnostic and Interventional Radiology, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany., Münch C; West German Cancer Center, Bridge Institute of Experimental Tumor Therapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, Partner Site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany.; German Cancer Consortium (DKTK), Partner Site Essen, Essen, Germany., Karakaya S; West German Cancer Center, Bridge Institute of Experimental Tumor Therapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, Partner Site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany.; German Cancer Consortium (DKTK), Partner Site Essen, Essen, Germany., Lueong SS; West German Cancer Center, Bridge Institute of Experimental Tumor Therapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, Partner Site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany.; German Cancer Consortium (DKTK), Partner Site Essen, Essen, Germany., Winkelkotte AM; West German Cancer Center, Bridge Institute of Experimental Tumor Therapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, Partner Site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany., Liffers ST; West German Cancer Center, Bridge Institute of Experimental Tumor Therapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, Partner Site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany.; German Cancer Consortium (DKTK), Partner Site Essen, Essen, Germany., Godfrey L; West German Cancer Center, Bridge Institute of Experimental Tumor Therapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, Partner Site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany.; German Cancer Consortium (DKTK), Partner Site Essen, Essen, Germany., Cheung PFY; West German Cancer Center, Bridge Institute of Experimental Tumor Therapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, Partner Site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany.; German Cancer Consortium (DKTK), Partner Site Essen, Essen, Germany., Savvatakis K; West German Cancer Center, Bridge Institute of Experimental Tumor Therapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, Partner Site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany.; German Cancer Consortium (DKTK), Partner Site Essen, Essen, Germany., Topping GJ; Department of Nuclear Medicine, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany., Englert F; Institute of Diagnostic and Interventional Radiology, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany., Kritzner L; Institute of Diagnostic and Interventional Radiology, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany., Grashei M; Department of Nuclear Medicine, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany., Tannapfel A; Institute of Pathology, Ruhr University of Bochum, Bochum, Germany., Viebahn R; Department of Surgery, Knappschaftskrankenhaus, Ruhr University Bochum, Bochum, Germany., Wolters H; Department of Visceral and General Surgery, St. Josef-Hospital, Dortmund, Germany., Uhl W; Clinic for General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum, Bochum, Germany., Vangala D; Department of Medicine, Ruhr University Bochum, University Hospital Knappschaftskrankenhaus Bochum GmbH, Bochum, Germany., Smeets EMM; Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands., Aarntzen EHJG; Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands., Rauh D; Faculty of Chemistry and Chemical Biology, TU Dortmund University, Dortmund, Germany.; Drug Discovery Hub Dortmund (DDHD) Am Zentrum Für Integrierte Wirkstoffforschung (ZIW), Dortmund, Germany., Weichert W; Institute of Pathology, TUM School of Medicine, Technical University of Munich, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.; Comprehensive Cancer Center Munich (CCCM), Munich, Germany., Hoheisel JD; Division of Functional Genome Analysis, German Cancer Research Center, DKFZ, Heidelberg, Germany., Hahn SA; Department of Molecular GI Oncology, Faculty of Medicine, Ruhr University Bochum, 44780, Bochum, Germany., Schilling F; Department of Nuclear Medicine, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany., Braren R; Institute of Diagnostic and Interventional Radiology, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany., Trajkovic-Arsic M; West German Cancer Center, Bridge Institute of Experimental Tumor Therapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. m.trajkovic-arsic@dkfz.de.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, Partner Site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany. m.trajkovic-arsic@dkfz.de.; German Cancer Consortium (DKTK), Partner Site Essen, Essen, Germany. m.trajkovic-arsic@dkfz.de., Siveke JT; West German Cancer Center, Bridge Institute of Experimental Tumor Therapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. j.siveke@dkfz.de.; Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, Partner Site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany. j.siveke@dkfz.de.; German Cancer Consortium (DKTK), Partner Site Essen, Essen, Germany. j.siveke@dkfz.de.

Publikováno v: Cancer & metabolism [Cancer Metab] 2022 Dec 09; Vol. 10 (1), pp. 24. Date of Electronic Publication: 2022 Dec 09.