Zobrazeno 1 - 10
of 979
pro vyhledávání: '"Heiner, Wedemeyer"'
Autor:
Sylvia M. Brakenhoff, Thymen Theijse, Peter van Wijngaarden, Christian Trautwein, Jonathan F. Brozat, Frank Tacke, Pieter Honkoop, Thomas Vanwolleghem, Dirk Posthouwer, Stefan Zeuzem, Ulrike Mihm, Heiner Wedemeyer, Thomas Berg, Solko W. Schalm, Robert J. de Knegt
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background and Aims Systematic reviews and medical guidelines are widely used in clinical practice. However, these are often not up-to-date and focussed on the average patient. We therefore aimed to evaluate a guideline add-on, TherapySelect
Externí odkaz:
https://doaj.org/article/c576f08441324371baa5a462203e8cd0
Autor:
Bahar Nalbant, Thorben Pape, Andrea Schneider, Benjamin Seeliger, Paul Schirmer, Benjamin Heidrich, Richard Taubert, Heiner Wedemeyer, Henrike Lenzen, Klaus Stahl
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Histopathological characterization obtained by transjugular liver biopsy (TJLB) may theoretically contribute to clarification of the exact aetiology of acute liver failure (ALF). It's unclear whether the histopathological informat
Externí odkaz:
https://doaj.org/article/4c3e08a0dcce4460a52945485bad09ac
Autor:
Michael Hermann Wißing, Toni Luise Meister, Maximilian Klaus Nocke, André Gömer, Mejrema Masovic, Leonard Knegendorf, Yannick Brüggemann, Verian Bader, Anindya Siddharta, Claus-Thomas Bock, Alexander Ploss, Scott P. Kenney, Konstanze F. Winklhofer, Patrick Behrendt, Heiner Wedemeyer, Eike Steinmann, Daniel Todt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Hepatitis E virus (HEV) is a long-neglected RNA virus and the major causative agent of acute viral hepatitis in humans. Recent data suggest that HEV has a very heterogeneous hypervariable region (HVR), which can tolerate major genomic rearra
Externí odkaz:
https://doaj.org/article/36a2243de9ad4d3885e1b54753f3ea25
Autor:
Marc Ringelhan, Svenja Schuehle, Maarten van de Klundert, Elena Kotsiliti, Marie-Laure Plissonnier, Suzanne Faure-Dupuy, Tobias Riedl, Sebastian Lange, Karin Wisskirchen, Frank Thiele, Cho-Chin Cheng, Detian Yuan, Valentina Leone, Ronny Schmidt, Juliana Hünergard, Fabian Geisler, Kristian Unger, Hana Algül, Roland M. Schmid, Roland Rad, Heiner Wedemeyer, Massimo Levrero, Ulrike Protzer, Mathias Heikenwalder
Publikováno v:
JHEP Reports, Vol 6, Iss 10, Pp 101128- (2024)
Background & Aims: Although most hepatocellular carcinoma (HCC) cases are driven by hepatitis and cirrhosis, a subset of patients with chronic hepatitis B develop HCC in the absence of advanced liver disease, indicating the oncogenic potential of hep
Externí odkaz:
https://doaj.org/article/ffc2a796c409435a93822963b60ef4ed
Autor:
Christian Niehaus, Sebastian Klein, Benedikt Strunz, Erich Freyer, Benjamin Maasoumy, Heiner Wedemeyer, Niklas K. Björkström, Anke R.M. Kraft, Markus Cornberg
Publikováno v:
JHEP Reports, Vol 6, Iss 6, Pp 101074- (2024)
Background & Aims: Patients with advanced cirrhosis often develop hepatic decompensation, which is accompanied by systemic inflammation and may eventually lead to acute-on-chronic liver failure. One important cause of systemic hyperinflammation is a
Externí odkaz:
https://doaj.org/article/25f9b1d137a244d5b0daaf623a9be220
Autor:
Yaojie Liang, Xufeng Luo, Stefan Schefczyk, Lorraine T. Muungani, Hui Deng, Baoju Wang, Hideo A. Baba, Mengji Lu, Heiner Wedemeyer, Hartmut H. Schmidt, Ruth Broering
Publikováno v:
JHEP Reports, Vol 6, Iss 4, Pp 101012- (2024)
Background & Aims: Hepatitis B surface antigen (HBsAg) drives hepatocarcinogenesis. Factors and mechanisms involved in this progression remain poorly defined, hindering the development of effective therapeutic strategies. Therefore, the mechanisms in
Externí odkaz:
https://doaj.org/article/021c294eb0fa4e82a3c04f7fbcee6c73
Autor:
Stefan Schefczyk, Xufeng Luo, Yaojie Liang, Mike Hasenberg, Bernd Walkenfort, Martin Trippler, Jonas Schuhenn, Kathrin Sutter, Mengji Lu, Heiner Wedemeyer, Hartmut H. Schmidt, Ruth Broering
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Hepatitis B virus (HBV)-transgenic mice exhibit competent innate immunity and are therefore an ideal model for considering intrinsic or cell-based mechanisms in HBV pathophysiology. A highly replicative model that has been little used, let a
Externí odkaz:
https://doaj.org/article/d8033cbdd44a4c2e8375ba24f2d4d013
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Patients with decompensated cirrhosis are at risk of developing acute kidney injury (AKI). Studies have suggested that inhibition of the Renin-Angiotensin System (RAS) has certain nephro- and hepatoprotective effects in patients with compens
Externí odkaz:
https://doaj.org/article/9deceffbb11243c5a2ae36f6c412b7c4
Autor:
Nadja Seltrecht, Matthias Hardtke-Wolenski, Konstantinos Iordanidis, Danny Jonigk, Melanie Galla, Axel Schambach, Laura Elisa Buitrago-Molina, Heiner Wedemeyer, Fatih Noyan, Elmar Jaeckel
Publikováno v:
Cells, Vol 13, Iss 14, p 1216 (2024)
Background: Solid organ transplantation is hindered by immune-mediated chronic graft dysfunction and the side effects of immunosuppressive therapy. Regulatory T cells (Tregs) are crucial for modulating immune responses post-transplantation; however,
Externí odkaz:
https://doaj.org/article/4429a14562044937a921119004b57d0a
Autor:
Alejandro Campos-Murguia, MD, Katharina Luise Hupa-Breier, MD, Björn Hartleben, MD, Heiner Wedemeyer, MD, Richard Taubert, MD, Bastian Engel, MD
Publikováno v:
Transplantation Direct, Vol 10, Iss 3, p e1592 (2024)
Background. The noninvasive detection of subclinical graft injury including subclinical T cell–mediated rejection (subTCMR) is one of the unresolved challenges after liver transplantation. Recently, serum C-X-C motif chemokine ligand 8 (CXCL8) was
Externí odkaz:
https://doaj.org/article/6fdf46a25c6d4fa8b5ae6b965ba0940f