Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Heiner, Appel"'
Autor:
Gounwa Awad, Toralf Roch, Ulrik Stervbo, Sviatlana Kaliszczyk, Anna Stittrich, Jan Hörstrup, Ocan Cinkilic, Heiner Appel, Larysa Natrus, Ludmila Gayova, Felix Seibert, Frederic Bauer, Timm Westhoff, Mikalai Nienen, Nina Babel
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 288-298 (2021)
While virus-specific antibodies are broadly recognized as correlates of protection, virus-specific T cells are important for direct clearance of infected cells. Failure to generate hepatitis B virus (HBV)-specific antibodies is well-known in patients
Externí odkaz:
https://doaj.org/article/777b12b352f44ab2b993d5db26ca8318
Autor:
Timm H. Westhoff, Ludmila Gayova, Gounwa Awad, L.V. Natrus, Ocan Cinkilic, Jan Hörstrup, Heiner Appel, Anna Stittrich, Ulrik Stervbo, Felix S. Seibert, Nina Babel, Toralf Roch, Frederic Bauer, Mikalai Nienen, Sviatlana Kaliszczyk
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss, Pp 288-298 (2021)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
While virus-specific antibodies are broadly recognized as correlates of protection, virus-specific T cells are important for direct clearance of infected cells. Failure to generate hepatitis B virus (HBV)-specific antibodies is well-known in patients
Autor:
Heiner Appel, Nina Babel, Krystallenia Paniskaki, Moritz Anft, Oliver Witzke, Adrian Doevelaar, Andrea Uhle, Timm H. Westhoff, Jan Hörstrup, Sebastian Dolff, Michael Frahnert, Thiemo Pfab, Ulrik Stervbo, Felix S. Seibert, Michael Barenbrock, Arturo Blazquez-Navarro, Bodo Hölzer, Eckhart Büssemaker, Sarah Skrzypczyk
Publikováno v:
Kidney International. 99:1489-1490
Autor:
Ellen M Moran, René Heydrich, Chin Teck Ng, Tajvur P Saber, Jennifer McCormick, Joachim Sieper, Heiner Appel, Ursula Fearon, Douglas J Veale
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e24048 (2011)
This study examines the expression of IL-17A-secreting cells within the inflamed synovium and the relationship to in vivo joint hypoxia measurements.IL-17A expression was quantified in synovial tissue (ST), serum and synovial fluid (SF) by immunohist
Externí odkaz:
https://doaj.org/article/761e7ea5daf84a189b92459f2977c265
Publikováno v:
Scandinavian Journal of Rheumatology. 44:296-301
Analysis of interleukin (IL)-6 serum levels in patients with ankylosing spondylitis (AS) has indicated that IL-6 might be a pro-inflammatory cytokine involved in AS. However, two placebo-controlled trials with monoclonal antibodies directed against t
Publikováno v:
Arthritis & Rheumatology. 66:1745-1754
Objective To unravel the mechanisms that control bony ankylosis in ankylosing spondylitis (AS). Methods Histomorphologic and histomorphometric analyses were performed on zygapophyseal joints obtained from 18 patients with AS, 9 patients with osteoart
Autor:
Heiner Appel, Joachim Sieper
Publikováno v:
The Journal of Rheumatology. 42:561-563
Ankylosing spondylitis (AS) is a chronic inflammatory disease predominantly affecting the axial skeleton, leading potentially to bone erosions, new bone formation, and ankylosis of the spine. The burden of disease is determined by the grade of acute
Autor:
Uta Syrbe, Hildrun Haibel, Jürgen Braun, Kristina Conrad, Denis Poddubnyy, Heiner Appel, Martin Rudwaleit, Joachim Sieper
Publikováno v:
Annals of the Rheumatic Diseases. 73:2137-2143
Objective To investigate the role of serum vascular endothelial growth factor (VEGF) as a predictor of radiographic spinal progression in patients with axial spondyloarthritis (axSpA). Methods Altogether, 172 patients with definite axSpA (95 with ank
Autor:
Joachim Sieper, Uwe Schlichting, J. Bleil, Uta Syrbe, Heiner Appel, Christoph Loddenkemper, Axel Hempfing, R. Maier
Publikováno v:
Arthritis & Rheumatism. 65:1522-1529
Objective The interleukin-12 (IL-12) family of cytokines has been suggested to play a critical role in inflammatory autoimmune diseases, and recent studies analyzing peripheral blood and synovial fluid from patients with spondyloarthritides suggest t
Autor:
Dietmar Krause, Mathura Vigneswaran, Elmar Schmitz-Bortz, Juergen Braun, Hans-Juergen Menne, Uta Kiltz, Friedrich Dybowski, Xenofon Baraliakos, Manfred Igelmann, Ludwig Kalthoff, Ertan Saracbasi-Zender, Soeren A. Peters, Heiner Appel
Publikováno v:
Rheumatology (Oxford, England). 56(1)
Objective NSAIDs are first-line therapy in axial SpA (axSpA). The proportion of patients responding to NSAIDs and differences between AS and non-radiographic axSpA (nr-axSpA) in this regard have not been studied in detail to date. The aim of this stu