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Autor:
Simon Gräber, Sabine Wege, Lena Gyulumyan, Claudia Rueckes-Nilges, Heike Scheuermann, Heimo Mairbaeurl, Marcus A. Mall, Lutz Naehrlich, Christian Dopfer, Rebecca Hyde, Azadeh Bagheri-Hanson, Sebastian Fischer, Marie Dorda, Burkhard Tuemmler, Stephanie Hirtz
Publikováno v:
Cystic fibrosis.
The combination of the CFTR corrector lumacaftor with the potentiator ivacaftor has recently been approved for the treatment of patients with cystic fibrosis (CF) homozygous for the Phe508del CFTR mutation. The pivotal phase 3 trials examined clinica