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Signal Biosynthesis Inhibition with Ambuic Acid as a Strategy To Target Antibiotic-Resistant Infections.

Autor: Todd DA; The University of North Carolina at Greensboro, Department of Chemistry and Biochemistry, Greensboro, North Carolina, USA., Parlet CP; Department of Microbiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Crosby HA; Department of Microbiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Malone CL; Department of Microbiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Heilmann KP; Department of Microbiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Horswill AR; Department of Microbiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA alex-horswill@uiowa.edu nadja_cech@uncg.edu.; Department of Veterans Affairs Iowa City Health Care System, Iowa City, Iowa, USA., Cech NB; The University of North Carolina at Greensboro, Department of Chemistry and Biochemistry, Greensboro, North Carolina, USA alex-horswill@uiowa.edu nadja_cech@uncg.edu.

Publikováno v: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2017 Jul 25; Vol. 61 (8). Date of Electronic Publication: 2017 Jul 25 (Print Publication: 2017).

Correction: Castanea sativa (European Chestnut) Leaf Extracts Rich in Ursene and Oleanene Derivatives Block Staphylococcus aureus Virulence and Pathogenesis without Detectable Resistance.

Autor: Quave CL, Lyles JT, Kavanaugh JS, Nelson K, Parlet CP, Crosby HA, Heilmann KP, Horswill AR

Publikováno v: PloS one [PLoS One] 2016 Sep 22; Vol. 11 (9), pp. e0163655. Date of Electronic Publication: 2016 Sep 22 (Print Publication: 2016).

Airway acidification initiates host defense abnormalities in cystic fibrosis mice.

Autor: Shah VS; Department of Medicine, University of Iowa, Iowa City, IA 52242, USA. Department of Molecular Physiology and Biophysics, Pappajohn Biomedical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA., Meyerholz DK; Department of Pathology, University of Iowa, Iowa City, IA 52242, USA., Tang XX; Department of Medicine, University of Iowa, Iowa City, IA 52242, USA. Howard Hughes Medical Institute, University of Iowa, Iowa City, IA 52242, USA., Reznikov L; Department of Medicine, University of Iowa, Iowa City, IA 52242, USA., Abou Alaiwa M; Department of Medicine, University of Iowa, Iowa City, IA 52242, USA., Ernst SE; Department of Medicine, University of Iowa, Iowa City, IA 52242, USA. Howard Hughes Medical Institute, University of Iowa, Iowa City, IA 52242, USA., Karp PH; Department of Medicine, University of Iowa, Iowa City, IA 52242, USA. Howard Hughes Medical Institute, University of Iowa, Iowa City, IA 52242, USA., Wohlford-Lenane CL; Department of Pediatrics University of Iowa, Iowa City, IA 52242, USA., Heilmann KP; Department of Microbiology, University of Iowa, Iowa City, IA 52242, USA., Leidinger MR; Department of Pathology, University of Iowa, Iowa City, IA 52242, USA., Allen PD; Department of Medicine, University of Iowa, Iowa City, IA 52242, USA., Zabner J; Department of Medicine, University of Iowa, Iowa City, IA 52242, USA., McCray PB Jr; Department of Pediatrics University of Iowa, Iowa City, IA 52242, USA. Department of Microbiology, University of Iowa, Iowa City, IA 52242, USA., Ostedgaard LS; Department of Medicine, University of Iowa, Iowa City, IA 52242, USA., Stoltz DA; Department of Medicine, University of Iowa, Iowa City, IA 52242, USA. Department of Molecular Physiology and Biophysics, Pappajohn Biomedical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA. Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, IA 52242, USA., Randak CO; Department of Pediatrics University of Iowa, Iowa City, IA 52242, USA., Welsh MJ; Department of Medicine, University of Iowa, Iowa City, IA 52242, USA. Department of Molecular Physiology and Biophysics, Pappajohn Biomedical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA. Howard Hughes Medical Institute, University of Iowa, Iowa City, IA 52242, USA.

Publikováno v: Science (New York, N.Y.) [Science] 2016 Jan 29; Vol. 351 (6272), pp. 503-7.