Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Heiko U. De Schepper"'
Autor:
Kathleen Van Malderen, Nikita Hanning, Helen Lambrechts, Tine Haverhals, Silke Van Marcke, Hannah Ceuleers, Joris G. De Man, Benedicte Y. De Winter, Kevin Lamote, Heiko U. De Schepper
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundIrritable bowel syndrome (IBS) is a chronic gastrointestinal disorder for which no diagnostic tools are currently available. Patients are diagnosed using the Rome IV criteria and subtyped into a diarrhea, constipation, or mixed phenotype ba
Externí odkaz:
https://doaj.org/article/e3edcc3938be4d40900ccfce4960eb1b
Autor:
Tom Breugelmans, Wout Arras, Baptiste Oosterlinck, Aranzazu Jauregui-Amezaga, Michaël Somers, Bart Cuypers, Kris Laukens, Joris G. De Man, Heiko U. De Schepper, Benedicte Y. De Winter, Annemieke Smet
Publikováno v:
Cells, Vol 12, Iss 9, p 1224 (2023)
Overexpression of the transmembrane mucin MUC13, as seen in inflammatory bowel diseases (IBD), could potentially impact barrier function. This study aimed to explore how inflammation-induced MUC13 disrupts epithelial barrier integrity by affecting ju
Externí odkaz:
https://doaj.org/article/79fcc329deff46e29a81767617d90535
Autor:
Kathleen Van Malderen, Benedicte Y. De Winter, Joris G. De Man, Heiko U. De Schepper, Kevin Lamote
Publikováno v:
EBioMedicine, Vol 54, Iss , Pp - (2020)
Volatile organic compounds (VOCs) are produced by the human metabolism, inflammation and gut microbiota and form the basis of innovative volatomics research. VOCs detected through breath and faecal analysis hence serve as attractive, non-invasive bio
Externí odkaz:
https://doaj.org/article/163e3c2da958469997a42a0b293dff06
Autor:
Nikita Hanning, Michelle De bruyn, Hannah Ceuleers, Tim Boogaerts, Maya Berg, Annemieke Smet, Heiko U. De Schepper, Jurgen Joossens, Alexander L. N. van Nuijs, Joris G. De Man, Koen Augustyns, Ingrid De Meester, Benedicte Y. De Winter
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 811 (2021)
Dysregulation of the protease–antiprotease balance in the gastrointestinal tract has been suggested as a mechanism underlying visceral hypersensitivity in conditions such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). We ai
Externí odkaz:
https://doaj.org/article/bfb9756fc6404ddbabce04e440fd583d
Autor:
Nikita Hanning, Rosanne Verboven, Joris G. De Man, Hannah Ceuleers, Heiko U. De Schepper, Annemieke Smet, Benedicte Y. De Winter
Publikováno v:
American journal of physiology : gastrointestinal and liver physiology
AIMS Animals involved in common laboratory procedures experience minor levels of stress. The direct effect of limited amounts of stress on gastrointestinal function has not been reported yet. Therefore, this study aimed to assess the effect of single
Autor:
Heiko U. De Schepper, Jasper Pannemans, Tze J. Lam, Ans Pauwels, Nathalie Rommel, Jan Tack, Tim Vanuytsel, Alexander Thys
Publikováno v:
Neurogastroenterology and motility
Introduction Colonic high-resolution manometry (HRM) is a novel, not widely used diagnostic method used in the final workup of chronic constipation before surgery. Since its introduction, different motor patterns have been defined. However, it remain
Autor:
Hannah Ceuleers, Nikita Hanning, Michelle De bruyn, Joris G De Man, Heiko U De Schepper, Qian Li, Liansheng Liu, Steven Abrams, Annemieke Smet, Jurgen Joossens, Koen Augustyns, Ingrid De Meester, Pankaj J Pasricha, Benedicte Y De Winter
Publikováno v:
Frontiers in pharmacology
Background: Serine proteases are believed to play a key role in the origin of abdominal pain in IBD and IBS. We previously demonstrated a reduction of visceral pain in a post-inflammatory IBS rat model after a single intraperitoneal or intracolonic a
Publikováno v:
Gastroenterology. 162:S-1033
Autor:
Kathleen Van Malderen, Nikita Hanning, Helen Lambrechts, Tine Haverhals, Silke Van Marcke, Joris De Man, Benedicte Y. De Winter, Kevin Lamote, Heiko U. De Schepper
Publikováno v:
Gastroenterology. 162:S-1076
Autor:
Jurgen Joossens, Annemieke Smet, Ingrid De Meester, Hannah Ceuleers, Nikita Hanning, Maya Berg, Joris G. De Man, Tim Boogaerts, Heiko U. De Schepper, Alexander L.N. van Nuijs, Koen Augustyns, Michelle De bruyn, Benedicte Y. De Winter
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 13, Iss 811, p 811 (2021)
Volume 13
Issue 6
Pharmaceutics, Vol 13, Iss 811, p 811 (2021)
Volume 13
Issue 6
Dysregulation of the protease–antiprotease balance in the gastrointestinal tract has been suggested as a mechanism underlying visceral hypersensitivity in conditions such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). We ai