Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Heiko Krissel"'
Autor:
Neil J. Clendeninn, Heiko Krissel, Prabhu Rajagopalan, Kimberly J. Manhard, David M. Wilson, Sonny Gunawan, Li-Tain Yeh, Zancong Shen, Jeffrey N. Miner, Cory Iverson, Diane P. Leffingwell, Lawrence Garbo, Morris Sherman, Aram F. Hezel, Joe J. Stephenson, Carlos H.R. Becerra, Fadi Braiteh, Anthony El-Khoueiry, Donald A. Richards, Alex A. Adjei
Grade 3 or 4 adverse events possibly related to refametinib or sorafenib, occurring in {greater than or equal to}2 patients in either cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6739762d5f3f88061cfa4f75b3d7bb26
https://doi.org/10.1158/1078-0432.22459308
https://doi.org/10.1158/1078-0432.22459308
Autor:
Neil J. Clendeninn, Heiko Krissel, Prabhu Rajagopalan, Kimberly J. Manhard, David M. Wilson, Sonny Gunawan, Li-Tain Yeh, Zancong Shen, Jeffrey N. Miner, Cory Iverson, Diane P. Leffingwell, Lawrence Garbo, Morris Sherman, Aram F. Hezel, Joe J. Stephenson, Carlos H.R. Becerra, Fadi Braiteh, Anthony El-Khoueiry, Donald A. Richards, Alex A. Adjei
Overview of dose-limiting toxicities and adverse events leading to discontinuation and relationship to study treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::258db69f0ab944ea9a5828a4ff6377c2
https://doi.org/10.1158/1078-0432.22459305
https://doi.org/10.1158/1078-0432.22459305
Autor:
Neil J. Clendeninn, Heiko Krissel, Prabhu Rajagopalan, Kimberly J. Manhard, David M. Wilson, Sonny Gunawan, Li-Tain Yeh, Zancong Shen, Jeffrey N. Miner, Cory Iverson, Diane P. Leffingwell, Lawrence Garbo, Morris Sherman, Aram F. Hezel, Joe J. Stephenson, Carlos H.R. Becerra, Fadi Braiteh, Anthony El-Khoueiry, Donald A. Richards, Alex A. Adjei
Refametinib geometric mean (% coefficient of variation) multiple-dose pharmacokinetic data on day 1 of course 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::543df570df003837b9fd1f2e8a53a365
https://doi.org/10.1158/1078-0432.22459299.v1
https://doi.org/10.1158/1078-0432.22459299.v1
Autor:
Neil J. Clendeninn, Heiko Krissel, Prabhu Rajagopalan, Kimberly J. Manhard, David M. Wilson, Sonny Gunawan, Li-Tain Yeh, Zancong Shen, Jeffrey N. Miner, Cory Iverson, Diane P. Leffingwell, Lawrence Garbo, Morris Sherman, Aram F. Hezel, Joe J. Stephenson, Carlos H.R. Becerra, Fadi Braiteh, Anthony El-Khoueiry, Donald A. Richards, Alex A. Adjei
Incidence of treatment-emergent adverse events, all grades, occurring in {greater than or equal to}20% of patients in either cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf1509851ce86e1c831f06bf4cb4c3c
https://doi.org/10.1158/1078-0432.22459311
https://doi.org/10.1158/1078-0432.22459311
Autor:
Neil J. Clendeninn, Heiko Krissel, Prabhu Rajagopalan, Kimberly J. Manhard, David M. Wilson, Sonny Gunawan, Li-Tain Yeh, Zancong Shen, Jeffrey N. Miner, Cory Iverson, Diane P. Leffingwell, Lawrence Garbo, Morris Sherman, Aram F. Hezel, Joe J. Stephenson, Carlos H.R. Becerra, Fadi Braiteh, Anthony El-Khoueiry, Donald A. Richards, Alex A. Adjei
CTC enumeration and pERK analysis in course 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9466f57cc4dc9356c8e18c20951a2d91
https://doi.org/10.1158/1078-0432.22459314
https://doi.org/10.1158/1078-0432.22459314
Autor:
Neil J. Clendeninn, Heiko Krissel, Prabhu Rajagopalan, Kimberly J. Manhard, David M. Wilson, Sonny Gunawan, Li-Tain Yeh, Zancong Shen, Jeffrey N. Miner, Cory Iverson, Diane P. Leffingwell, Lawrence Garbo, Morris Sherman, Aram F. Hezel, Joe J. Stephenson, Carlos H.R. Becerra, Fadi Braiteh, Anthony El-Khoueiry, Donald A. Richards, Alex A. Adjei
pERK levels in hair follicles by dose level and course
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd6316716f41142f3238c30b48b2bfe
https://doi.org/10.1158/1078-0432.22459317.v1
https://doi.org/10.1158/1078-0432.22459317.v1
Autor:
Won Young Tak, Chia-Jui Yen, Michael Jeffers, Heiko Krissel, Prabhu Rajagopalan, Christian Kappeler, Wen-Son Hsieh, Miah Hiang Tay, Joong-Won Park, Winnie Yeo, Ronnie T.P. Poon, Kun-Ming Rau, Chiun Hsu, Jung-Hwan Yoon, Cheng-Yao Lin, Hye Jin Choi, Jeong Heo, Ho Yeong Lim
Supplementary Figure 1. CONSORT diagram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180df5bebc37f2e679e0de974f8d88c2
https://doi.org/10.1158/1078-0432.22456302
https://doi.org/10.1158/1078-0432.22456302
Autor:
Won Young Tak, Chia-Jui Yen, Michael Jeffers, Heiko Krissel, Prabhu Rajagopalan, Christian Kappeler, Wen-Son Hsieh, Miah Hiang Tay, Joong-Won Park, Winnie Yeo, Ronnie T.P. Poon, Kun-Ming Rau, Chiun Hsu, Jung-Hwan Yoon, Cheng-Yao Lin, Hye Jin Choi, Jeong Heo, Ho Yeong Lim
Supplementary Tables. Supplementary Table 1. Pre-defined dose modification levels for sorafenib and refametinib Supplementary Table 2. Single-dose refametinib and its metabolite M17 geometric mean (% coefficient of variation) pharmacokinetic paramete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723652d45a76c05ae38d12a62f86e020
https://doi.org/10.1158/1078-0432.22456299.v1
https://doi.org/10.1158/1078-0432.22456299.v1
Autor:
Neil J. Clendeninn, Heiko Krissel, Prabhu Rajagopalan, Kimberly J. Manhard, David M. Wilson, Sonny Gunawan, Li-Tain Yeh, Zancong Shen, Jeffrey N. Miner, Cory Iverson, Diane P. Leffingwell, Lawrence Garbo, Morris Sherman, Aram F. Hezel, Joe J. Stephenson, Carlos H.R. Becerra, Fadi Braiteh, Anthony El-Khoueiry, Donald A. Richards, Alex A. Adjei
Refametinib geometric mean (% coefficient of variation) single-dose pharmacokinetic data on day 1 of course 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd5825afc1dec4cf18caa3e3953f977
https://doi.org/10.1158/1078-0432.22459302
https://doi.org/10.1158/1078-0432.22459302
Autor:
Neil J. Clendeninn, Heiko Krissel, Prabhu Rajagopalan, Kimberly J. Manhard, David M. Wilson, Sonny Gunawan, Li-Tain Yeh, Zancong Shen, Jeffrey N. Miner, Cory Iverson, Diane P. Leffingwell, Lawrence Garbo, Morris Sherman, Aram F. Hezel, Joe J. Stephenson, Carlos H.R. Becerra, Fadi Braiteh, Anthony El-Khoueiry, Donald A. Richards, Alex A. Adjei
Sorafenib geometric mean (% coefficient of variation) multiple-dose pharmacokinetic data on day 1 of course 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6375ada22e2e2f8af152ed639f435bc4
https://doi.org/10.1158/1078-0432.22459296
https://doi.org/10.1158/1078-0432.22459296