Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Heiko Kilter"'
Autor:
Heiko Kilter, Michael Böhm
Publikováno v:
DoctorConsult - The Journal. Wissen für Klinik und Praxis. 2:e81-e86
Autor:
Heiko Kilter, Michael Böhm
Publikováno v:
DoctorConsult - The Journal. Wissen für Klinik und Praxis. 2:e139-e144
Publikováno v:
Medizinische Klinik. 102:647-658
This article reviews advances in cardiovascular medicine published last year. The following issues are reported in detail: (1) risk factors and lifestyle, (2) computed tomography in coronary artery disease, (3) revascularization in cardiogenic shock,
Publikováno v:
Experimental Cell Research. 313:921-930
Hepatocyte growth factor (HGF) is a pleiotropic cytokine promoting proliferation, migration and survival in several cell types. HGF and its cognate receptor c-Met are expressed in cardiac cells during early cardiogenesis, but data concerning its role
Publikováno v:
Cardiovascular Research. 71:342-351
Reactive oxygen species (ROS) contribute to the pathogenesis of myocardial hypertrophy. NADPH oxidase is a major source of ROS production. The small GTPase Rac1 mediates the activation of NADPH oxidase; however, the mechanism of Rac1 activation is in
Autor:
Ashour Michael, Robert N. Solomon, Jeffery D. Molkentin, Richard D. Patten, Syed Haq, Ronglih Liao, Zhili Shao, Lei Cui, Muthu Periasamy, Thomas Force, Michele Andreucci, Eileen Hsich, Xin Chen, Kausik Bhattacharya, Heiko Kilter, Gordon S. Huggins, Brian Walters
Publikováno v:
Journal of Biological Chemistry. 279:21383-21393
Glycogen synthase kinase (GSK) 3beta is a negative regulator of stress-induced cardiomyocyte hypertrophy. It is not clear, however, if GSK-3beta plays any role in regulating normal cardiac growth and cardiac function. Herein we report that a transgen
Autor:
Heiko Kilter, Michael Böhm
Publikováno v:
Herz. 29:239-247
The heart failure syndrome is one the most common chronic diseases in western countries with poor prognosis. In view of the estimated aging of our society, it will gain further importance. Hypertension and/or myocardial infarction are the main causes
Autor:
Georg Nickenig, Ulrich Laufs, Heiko Kilter, Hans-Joachim Schäfers, Michael Böhm, Tanja Kartes, Christoph Maack
Publikováno v:
Circulation. 108:1567-1574
Background— Reactive oxygen species (ROS) contribute to the development of heart failure. A potential source of myocardial ROS is the NADPH oxidase, which is regulated by the small GTP-binding protein rac1. Isoprenylation of rac1 can be inhibited b
Autor:
Kausik Bhattacharya, James R. Woodgett, Brian F. Walters, Ashour Michael, Heiko Kilter, Syed Haq, Paolo Dotto, Michele Andreucci, Thomas Force
Publikováno v:
Proceedings of the National Academy of Sciences. 100:4610-4615
β-Catenin is a transcriptional activator that regulates embryonic development as part of the Wnt pathway and also plays a role in tumorigenesis. The mechanisms leading to Wnt-induced stabilization of β-catenin, which results in its translocation to
Publikováno v:
Journal of Cardiac Failure. 8:S351-S358
Stretch of cardiomyocytes in vivo occurs in response to a number of stimuli, including pressure or volume overload, but it is most clearly seen following relatively large, acute myocardial infarctions. It is in this setting that stretch is most clear