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of 8
pro vyhledávání: '"Heiko Büth"'
Autor:
Tripti Tamhane, Robin W. Njenga, Roberta E. Burden, Heiko Büth, Gunhild M. Maelandsmo, Mads H. Haugen, Christopher J. Scott, Klaudia Brix
Publikováno v:
Applied Sciences, Vol 11, Iss 24, p 11936 (2021)
Cathepsin B is an endo-lysosomal cysteine protease. However, its increased expression and altered localization to the extracellular space, to mitochondria, or to the nucleus has been linked to tumor progression. In the present study, we show enhanced
Externí odkaz:
https://doaj.org/article/36dd7bfb93564673ba3364d600283128
Publikováno v:
Journal of Biotechnology. 148:83-90
Human mesenchymal stem cells are promising candidates for cell-based therapies since they have the capacity to differentiate into a variety of cell types. However, the acceptance of hMSCs for clinical applications as well as in vitro tissue models wi
Autor:
Norbert Schaschke, Stefanie R. Dannenmann, Raluca Ostafe, Maren Rehders, Klaudia Brix, Petra Boukamp, Pier Luigi Buttigieg, Hans Jürgen Stark, Heiko Büth
Publikováno v:
European Journal of Cell Biology. 86:747-761
Migration, proliferation and differentiation of keratinocytes are important processes during tissue regeneration and wound healing of the skin. Here, we focussed on proteases that contribute to extracellular matrix (ECM) remodeling as a prerequisite
Autor:
Roland Meier-Bornheim, Maren Hansen, Benedikt Hartwig, Henrike Veith, Norbert Schaschke, Brit K. Wolters, Heiko Büth, Werner Machleidt, Christian P. Sommerhoff, Klaudia Brix, Petra Boukamp, Norbert E. Fusenig
Publikováno v:
European Journal of Cell Biology. 83:781-795
Cathepsin B, a lysosomal cysteine proteinase, was detected within vesicles of cellular protrusions forming cell-cell contact sites between keratinocytes of the stratum spinosum of human skin. This observation suggested the possibility that secretion
Autor:
Blanca Arango-Gonzalez, Milada Šírová, Hagen Thielecke, Sylvie Julien, Etienne Schacht, Ulrich Schraermeyer, Eberhart Zrenner, Blanka Rihova, Heiko Büth, Tobias Peters, Pavel Rossmann, Sandra Van Vlierberghe, Peter Dubruel, Susanne C. Beck, Focke Ziemssen
Publikováno v:
Biomaterials. 32(16)
Subretinal implants aim to replace the photoreceptor function in patients suffering from degenerative retinal disease by topically applying electrical stimuli in the subretinal space. Critical obstacles in the design of high-resolution subretinal imp
Autor:
Peter Dubruel, Vincent Vermeersch, Hagen Thielecke, Heiko Büth, Veska Toncheva, Adam Sossalla, Christian M. Kurz, Etienne Schacht
Publikováno v:
Biosensorsbioelectronics. 26(8)
There is a lack of methods suitable for generation of data about the dynamics of effects on cell membranes with a high sensitivity. Such methods are urgently needed to support the optimisation of interaction of substances, particles or materials with
Publikováno v:
Tissuecell. 43(2)
For studying cellular processes three-dimensional (3D) in vitro models are of a high importance. For tissue engineering approaches osseous differentiation is performed on 3D scaffolds, but material depending influences promote cellular processes like
Publikováno v:
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. 191(1)
In this study the critical parameters directing osteogenic differentiation of umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) were investigated, key factors and conditions identified and improved protocols for a more cell-type adapted