Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Heiko Bernsmann"'
Autor:
Bernard Feringa, Rob Hoen, Jeroen A. F. Boogers, Johannes G. de Vries, Heiko Bernsmann, Adriaan J. Minnaard, A. Meetsma, Theodora D. Tiemersma-Wegman, André H.M. de Vries
Publikováno v:
Angewandte Chemie-International Edition, 44(27), 4209-4212. WILEY-V C H VERLAG GMBH
ChemInform, 36(44)
ChemInform, 36(44)
Autor:
Birgit Wibbeling, Viktor O. Rogatchov, Peter Metz, Pia Schwab, Roland Fröhlich, Heiko Bernsmann
Publikováno v:
Tetrahedron Letters. 43:4753-4756
Enantiomerically pure δ- and γ-sultams have been prepared by intramolecular [4+2] cycloaddition of N-1-phenylethyl substituted vinylsulfonamides with purely thermal activation and under high pressure. An optimized procedure for reductive debenzylat
Publikováno v:
Tetrahedron. 58:4451-4457
Novel THF-amino acids were efficiently synthesized from actic acid methyl esters. The conformational restriction imposed by the 2,5-cis disubstituted tetrahydrofuran moiety is apparent from their facile cyclization to give medium-sized lactams.
Publikováno v:
Tetrahedron Letters. 42:5377-5380
Starting from a key intermediate for the synthesis of the larger hydroxy acid constituent of pamamycin-607 ( 1 ), an efficient three-step route to the methyl ester of the smaller fragment of 1 involving a Yamaguchi lactonization with concomitant C(2)
Publikováno v:
Tetrahedron Letters. 41:7629-7633
The enantiomerically pure methyl ester of the complete larger hydroxy acid (C(1)C(18)) of the macrodiolide antibiotic pamamycin-607 has been synthesized using a general sultone route to actic acids and analogs. The requisite N , N -dimethylamino m
Publikováno v:
Tetrahedron Letters. 41:4347-4351
A highly advanced enantiomerically pure C(1)–C(18) precursor of the larger fragment of the macrodiolide pamamycin-607 has been synthesized. The stereotriad C(7)–C(9) between the two heterocyclic rings of the target was generated using a diastereo
Publikováno v:
Tetrahedron Letters. 41:1721-1724
Using sultone chemistry, a short and highly enantioselective synthesis of an advanced precursor for the larger hydroxy acid moiety and of the complete smaller hydroxy acid portion of the macrodiolide antibiotic pamamycin-607 has been accomplished.
Publikováno v:
ChemInform. 31
Publikováno v:
ChemInform. 31
Publikováno v:
ChemInform. 32