Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Heiko, Singer"'
Autor:
Michael Schwenkert, Christoph Stein, Georg H. Fey, Andreas Mackensen, Fuat Oduncu, Markus Kügler, Kristin Mentz, Bernhard Stockmeyer, Ingo Schubert, Christian Kellner, Heiko Singer, Domenica Saul
Publikováno v:
British Journal of Haematology. 150:574-586
Two trivalent constructs consisting of single-chain Fv antibody fragments (scFvs) specific for the interleukin-3 receptor alpha chain (CD123), CD33 and the Fcgamma-receptor III (CD16) were designed and characterized for the elimination of acute myelo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::508f4f01b614ad3fa0197800eb643ee6
https://doi.org/10.1111/j.1365-2141.2010.08300.x
https://doi.org/10.1111/j.1365-2141.2010.08300.x
Autor:
Georg H. Fey, Kristin Mentz, Christian Kellner, Michael Schwemmlein, Christoph Stein, Andreas Mackensen, Bernhard Stockmeyer, Harald Lanig, Heiko Singer, Michael Aigner, Fuat Oduncu
Publikováno v:
Journal of Immunotherapy. 33:599-608
Single-chain Fv triplebodies (sctb), consisting of a single polypeptide chain with 3 single-chain antibody variable fragments connected in tandem, were generated as antileukemic agents. A CD19-specific sctb of this format has previously been shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed40a273f994245bfd9ccd9161a417c6
https://doi.org/10.1097/cji.0b013e3181dda225
https://doi.org/10.1097/cji.0b013e3181dda225
Autor:
Christian Kellner, Julia Stieglmaier, Georg H. Fey, Kristin Mentz, Peter Lang, Michael Schwenkert, Michael Schwemmlein, Matthias Peipp, Bernhard Stockmeyer, Fuat Oduncu, Joerg Bruenke, Heiko Singer
Publikováno v:
Journal of Immunotherapy. 31:871-884
A novel bispecific antibody-derived recombinant protein targeting leukemias and lymphomas was designed, a single-chain Fv triple body (sctb) consisting of 1 polypeptide chain with 3 scFvs connected in tandem. The distal scFvs were specific for the tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9d7ae63359bbe4f87b7b5e409e79ed
https://doi.org/10.1097/cji.0b013e318186c8b4
https://doi.org/10.1097/cji.0b013e318186c8b4
Autor:
Ingo Schubert, Andreas Mackensen, Michael Schwenkert, Domenica Saul, Christoph Stein, Kristin Mentz, Wolfgang Hillen, Georg H. Fey, Christian Kellner, Bernhard Stockmeyer, Heiko Singer, Markus Kügler
A single-chain triplebody (sctb) 33-ds16-ds19 comprising two distal single-chain Fv fragments (scFvs) specific for the lymphoid antigen CD19 and the myeloid antigen CD33 flanking a central scFv specific for CD16, which is the low affinity Fc-receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1829224576db9d26b73db6669177fb5e
https://europepmc.org/articles/PMC3038008/
https://europepmc.org/articles/PMC3038008/
Autor:
Markus, Kügler, Christoph, Stein, Christian, Kellner, Kristin, Mentz, Domenica, Saul, Michael, Schwenkert, Ingo, Schubert, Heiko, Singer, Fuat, Oduncu, Bernhard, Stockmeyer, Andreas, Mackensen, Georg H, Fey
Publikováno v:
British journal of haematology. 150(5)
Two trivalent constructs consisting of single-chain Fv antibody fragments (scFvs) specific for the interleukin-3 receptor alpha chain (CD123), CD33 and the Fcgamma-receptor III (CD16) were designed and characterized for the elimination of acute myelo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3bd22405b01fa14cca6888075dd8ad08
https://pubmed.ncbi.nlm.nih.gov/20636437
https://pubmed.ncbi.nlm.nih.gov/20636437