Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Heiko, Singer"'
Autor:
Michael Schwenkert, Christoph Stein, Georg H. Fey, Andreas Mackensen, Fuat Oduncu, Markus Kügler, Kristin Mentz, Bernhard Stockmeyer, Ingo Schubert, Christian Kellner, Heiko Singer, Domenica Saul
Publikováno v:
British Journal of Haematology. 150:574-586
Two trivalent constructs consisting of single-chain Fv antibody fragments (scFvs) specific for the interleukin-3 receptor alpha chain (CD123), CD33 and the Fcgamma-receptor III (CD16) were designed and characterized for the elimination of acute myelo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::508f4f01b614ad3fa0197800eb643ee6
https://doi.org/10.1111/j.1365-2141.2010.08300.x
https://doi.org/10.1111/j.1365-2141.2010.08300.x
Autor:
Georg H. Fey, Kristin Mentz, Christian Kellner, Michael Schwemmlein, Christoph Stein, Andreas Mackensen, Bernhard Stockmeyer, Harald Lanig, Heiko Singer, Michael Aigner, Fuat Oduncu
Publikováno v:
Journal of Immunotherapy. 33:599-608
Single-chain Fv triplebodies (sctb), consisting of a single polypeptide chain with 3 single-chain antibody variable fragments connected in tandem, were generated as antileukemic agents. A CD19-specific sctb of this format has previously been shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed40a273f994245bfd9ccd9161a417c6
https://doi.org/10.1097/cji.0b013e3181dda225
https://doi.org/10.1097/cji.0b013e3181dda225
Autor:
Christian Kellner, Julia Stieglmaier, Georg H. Fey, Kristin Mentz, Peter Lang, Michael Schwenkert, Michael Schwemmlein, Matthias Peipp, Bernhard Stockmeyer, Fuat Oduncu, Joerg Bruenke, Heiko Singer
Publikováno v:
Journal of Immunotherapy. 31:871-884
A novel bispecific antibody-derived recombinant protein targeting leukemias and lymphomas was designed, a single-chain Fv triple body (sctb) consisting of 1 polypeptide chain with 3 scFvs connected in tandem. The distal scFvs were specific for the tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9d7ae63359bbe4f87b7b5e409e79ed
https://doi.org/10.1097/cji.0b013e318186c8b4
https://doi.org/10.1097/cji.0b013e318186c8b4
Autor:
Ingo Schubert, Andreas Mackensen, Michael Schwenkert, Domenica Saul, Christoph Stein, Kristin Mentz, Wolfgang Hillen, Georg H. Fey, Christian Kellner, Bernhard Stockmeyer, Heiko Singer, Markus Kügler
A single-chain triplebody (sctb) 33-ds16-ds19 comprising two distal single-chain Fv fragments (scFvs) specific for the lymphoid antigen CD19 and the myeloid antigen CD33 flanking a central scFv specific for CD16, which is the low affinity Fc-receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1829224576db9d26b73db6669177fb5e
https://europepmc.org/articles/PMC3038008/
https://europepmc.org/articles/PMC3038008/
Autor:
Markus, Kügler, Christoph, Stein, Christian, Kellner, Kristin, Mentz, Domenica, Saul, Michael, Schwenkert, Ingo, Schubert, Heiko, Singer, Fuat, Oduncu, Bernhard, Stockmeyer, Andreas, Mackensen, Georg H, Fey
Publikováno v:
British journal of haematology. 150(5)
Two trivalent constructs consisting of single-chain Fv antibody fragments (scFvs) specific for the interleukin-3 receptor alpha chain (CD123), CD33 and the Fcgamma-receptor III (CD16) were designed and characterized for the elimination of acute myelo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3bd22405b01fa14cca6888075dd8ad08
https://pubmed.ncbi.nlm.nih.gov/20636437
https://pubmed.ncbi.nlm.nih.gov/20636437
Autor:
Bianca Birkorth
Elli und Heiko sind ein glückliches Paar. Weil Heiko die Gelegenheit geboten wird, sich beruflich weiter zu entwickeln, steht ein Umzug an. Hamburg, London oder Barcelona? Sie sind erleichtert, als die Entscheidung auf Hamburg fällt. Ausgerechnet z