Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Heiko, Lemcke"'
Autor:
Kai Budde-Sagert, Simone Krueger, Clemens Sehlke, Heiko Lemcke, Anika Jonitz-Heincke, Robert David, Rainer Bader, Adelinde M Uhrmacher
Publikováno v:
Bioinformatics and Biology Insights, Vol 18 (2024)
Background and objective: The primary cilium is a small protrusion found on most mammalian cells. It acts as a cellular antenna, being involved in various cell signaling pathways. The length of the primary cilium affects its function. To study the im
Externí odkaz:
https://doaj.org/article/37ac815ba5cf4444b6aef48aad7c7df9
Autor:
Moritz Schweins, Ralf Gäbel, Matti Raitza, Praveen Vasudevan, Heiko Lemcke, Markus Joksch, Anna Schildt, Jens Kurth, Tobias Lindner, Felix G. Meinel, Alper Öner, Hüseyin Ince, Brigitte Vollmar, Bernd Joachim Krause, Robert David, Cajetan Immanuel Lang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-9 (2024)
Abstract Background The initial idea of functional tissue replacement has shifted to the concept that injected cells positively modulate myocardial healing by a non-specific immune response of the transplanted cells within the target tissue. This all
Externí odkaz:
https://doaj.org/article/d4f4b7deaea14d3b9933b1f46db2fc8a
Autor:
Monica Cattaneo, Aneta Aleksova, Alberto Malovini, Elisa Avolio, Anita Thomas, Valeria Vincenza Alvino, Michael Kilcooley, Marie Pieronne-Deperrois, Antoine Ouvrard-Pascaud, Anna Maciag, Gaia Spinetti, Sophie Kussauer, Heiko Lemcke, Anna Skorska, Praveen Vasudevan, Stefania Castiglione, Angela Raucci, Robert David, Vincent Richard, Antonio Paolo Beltrami, Paolo Madeddu, Annibale Alessandro Puca
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-11 (2023)
Abstract Long-living individuals (LLIs) escape age-related cardiovascular complications until the very last stage of life. Previous studies have shown that a Longevity-Associated Variant (LAV) of the BPI Fold Containing Family B Member 4 (BPIFB4) gen
Externí odkaz:
https://doaj.org/article/348033df59064add9787c0ed75ff9450
Autor:
Oleksandra Chabanovska, Heiko Lemcke, Hermann Lang, Brigitte Vollmar, Pascal M. Dohmen, Robert David, Christian Etz, Catharina Neßelmann
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Investigating native human cardiac tissue with preserved 3D macro- and microarchitecture is fundamental for clinical and basic research. Unfortunately, the low accessibility of the human myocardium continues to limit scientific progress. To
Externí odkaz:
https://doaj.org/article/f4c1da296e2a45db8d375306a4daae91
Autor:
Praveen Vasudevan, Markus Wolfien, Heiko Lemcke, Cajetan Immanuel Lang, Anna Skorska, Ralf Gaebel, Anne-Marie Galow, Dirk Koczan, Tobias Lindner, Wendy Bergmann, Brigitte Mueller-Hilke, Brigitte Vollmar, Bernd Joachim Krause, Olaf Wolkenhauer, Gustav Steinhoff, Robert David
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-18 (2023)
Abstract Background The immune response is a crucial factor for mediating the benefit of cardiac cell therapies. Our previous research showed that cardiomyocyte transplantation alters the cardiac immune response and, when combined with short-term pha
Externí odkaz:
https://doaj.org/article/c1342d67edd547f692361732bde8fead
Autor:
Inken Salewski, Julia Henne, Leonie Engster, Paula Krone, Bjoern Schneider, Caterina Redwanz, Heiko Lemcke, Larissa Henze, Christian Junghanss, Claudia Maletzki
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Mismatch repair-deficient (dMMR) tumors show a good response toward immune checkpoint inhibitors (ICI), but developing resistance impairs patients’ outcomes. Here, we compared the therapeutic potential of an α-PD-L1 antibody with the CDK4/6 inhibi
Externí odkaz:
https://doaj.org/article/3e095849514f4debaf0bafdf03f37cc7
Expedient assessment of post-infarct remodeling by native cardiac magnetic resonance imaging in mice
Autor:
Cajetan Immanuel Lang, Praveen Vasudevan, Piet Döring, Ralf Gäbel, Heiko Lemcke, Tobias Lindner, Gustav Steinhoff, Bernd Joachim Krause, Brigitte Vollmar, Felix G. Meinel, Seyrani Yücel, Alper Öner, Hüseyin Ince, Robert David
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Novel therapeutic strategies aiming at improving the healing process after an acute myocardial infarction are currently under intense investigation. The mouse model plays a central role for deciphering the underlying mechanisms on a molecula
Externí odkaz:
https://doaj.org/article/3da395c736904befa2a3897a682bd2c2
Autor:
Cajetan Immanuel Lang, Anika Dahmen, Praveen Vasudevan, Heiko Lemcke, Ralf Gäbel, Alper Öner, Hüseyin Ince, Robert David, Markus Wolfien
Publikováno v:
Cytotherapy. 25:640-652
Autor:
Beschan Ahmad, Anna Skorska, Markus Wolfien, Haval Sadraddin, Heiko Lemcke, Praveen Vasudevan, Olaf Wolkenhauer, Gustav Steinhoff, Robert David, Ralf Gaebel
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 8843 (2022)
Ventricular arrhythmias associated with myocardial infarction (MI) have a significant impact on mortality in patients following heart attack. Therefore, targeted reduction of arrhythmia represents a therapeutic approach for the prevention and treatme
Externí odkaz:
https://doaj.org/article/f0ab944d528f43138dac8a0667cc296c
Autor:
Frauke Thiele, Christin Voelkner, Vivien Krebs, Paula Müller, Julia Jeannine Jung, Christian Rimmbach, Gustav Steinhoff, Thomas Noack, Robert David, Heiko Lemcke
Publikováno v:
Cellular Physiology and Biochemistry, Vol 53, Iss 2, Pp 337-354 (2019)
Externí odkaz:
https://doaj.org/article/ea29815f028840a69d5ed6a39537b29d