Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Heikki Wuorela"'
Publikováno v:
Pharmacology & Toxicology. 77:327-332
Intracellular free calcium regulates contraction-relaxation processes in vascular smooth muscle. We compared intraplatelet free calcium ([Ca 2+ ] i ) and pH ([pH] i ) in hypertensive pregnant women to those in normotensive pregnant and non-pregnant w
Autor:
Heikki Vapaatalo, Elise Siltaloppi, Pauli Vuorinen, Eeva Moilanen, Heikki Wuorela, Hannu Kankaanranta
Publikováno v:
Scopus-Elsevier
The present work was designed to study the pharmacological control of the receptor-mediated activation of human neutrophils by tolfenamic acid (2(-)[(3-chloro-2-methylphenyl)-amino]benzoic acid). Tolfenamic acid inhibited in a concentration-dependent
Publikováno v:
Pharmacology & Toxicology. 74:167-173
In order to further clarify differences between spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto (WKY) rats as well as the effects of ageing, vascular smooth muscle responses of mesenteric arterial rings and intracellular free calc
Autor:
Mika Kähönen, Heikki Mäkynen, Pertti Arvola, Ilkka Pörsti, Vesa Manninen, Heikki Vapaatalo, Heikki Wuorela
Publikováno v:
Journal of Cardiovascular Pharmacology. 22:702-705
Several studies have shown that increased dietary calcium decreases blood pressure (BP) in spontaneously hypertensive rats (SHR), but the underlying mechanisms are not fully understood. We compared the effects of a high calcium diet and different ant
Autor:
Heikki Wuorela
Publikováno v:
Pharmacology & Toxicology. 71:376-382
The effects of calcium supplementation on blood pressure, intracellular free calcium concentration ([Ca2+],) and rate of Na+-H+ exchange were studied in DOC-NaCl-hypertensive rats. All the animals were uninephrectomized and divided into two main grou
Publikováno v:
Pharmacology & Toxicology. 70:105-110
The second derivative of developed tension (T", d2T/dt2) has not come into common use in the analysis of cardiac contractility, although it has been shown to give additional information on the myocardial contraction-relaxation cycle (CRC). In the pre
Autor:
Heini Huhtala, Pertti Arvola, M Ilkka, Ilkka Pörsti, P Säynävälammi, T Metsä-Ketelä, Heikki Wuorela, Heikki Vapaatalo
Publikováno v:
Journal of Hypertension. 8:835-841
The effects of calcium and deoxycorticosterone (DOC) were studied in four groups of spontaneously hypertensive rats (SHR): control, calcium, DOC and DOC + calcium. Calcium was administered in drinking fluid as 1.5% calcium chloride, and DOC was injec
Autor:
Timo Metsä-Ketelä, Säynävälammi P, Pekka Laippala, Heikki Vapaatalo, Heikki Wuorela, Pertti Arvola, Nurmi Ak, Ilkka Pörsti, Heini Huhtala
Publikováno v:
Clinical and Experimental Hypertension. Part A: Theory and Practice. 12:1159-1174
The effects of calcium and deoxycorticosterone (DOC) on blood pressure, plasma renin activity (PRA), urinary sodium excretion and aortic responses were studied in spontaneously hypertensive rats (SHR). The animals (age 9 weeks) were divided into four
Autor:
Timo Metsä-Ketelä, Keikki Riekkinen, Raimo Ojanen, Seppo Kaukinen, Liisa Kaukinen, Heikki Wuorela
Publikováno v:
Scandinavian Journal of Thoracic and Cardiovascular Surgery. 24:71-73
Metabolic indicators of myocardial ischaemia were measured in coronary sinus blood in six patients undergoing coronary artery bypass grafting (CABG). Five arterial and coronary sinus blood samples were taken in each case--one before cardiopulmonary b
Publikováno v:
The American journal of physiology. 270(4 Pt 2)
We tested the effect of high-Ca2+ diet on blood pressure and responses of mesenteric arterial rings in vitro in established deoxycorticosterone (DOC)-NaCl hypertension. Ca2+ supplementation (2.5%) of Wistar rats, which was commenced 8 wk after initia