Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Heikki Turunen"'
Autor:
Simon Pacouret, Eva Andres-Mateos, Ru Xiao, Eva Plovie, Vadim Khaychuk, Luk H. Vandenberghe, Livia S. Carvalho, Rajani Shelke, Heikki Turunen, Samiksha Shah, Eric Zinn, Anna C. Maurer
Publikováno v:
Cell Reports, Vol 12, Iss 6, Pp 1056-1068 (2015)
SummaryAdeno-associated virus (AAV) vectors have emerged as a gene-delivery platform with demonstrated safety and efficacy in a handful of clinical trials for monogenic disorders. However, limitations of the current generation vectors often prevent b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2e0f8c5558fcf6c09160e51d19c145
https://doi.org/10.1016/j.celrep.2015.07.019
https://doi.org/10.1016/j.celrep.2015.07.019
Autor:
Eva Andres-Mateos, Frédéric Broucque, Rajani Shelke, Ru Xiao, Magalie Penaud-Budloo, Trisha Barungi, Eduard Ayuso, Anna C. Maurer, Heikki Turunen, Véronique Blouin, Mathieu Mével, Luk H. Vandenberghe, Philippe Moullier, Mohammed Bouzelha, Simon Pacouret
Publikováno v:
Molecular Therapy
Molecular Therapy, Cell Press, 2017, 25 (6), pp.1375-1386. ⟨10.1016/j.ymthe.2017.04.001⟩
Molecular Therapy, Cell Press, 2017, 25 (6), pp.1375-1386. ⟨10.1016/j.ymthe.2017.04.001⟩
International audience; Adeno-associated virus (AAV) vectors are promising clinical candidates for therapeutic gene transfer, and a number of AAV-based drugs may emerge on the market over the coming years. To insure the consistency in efficacy and sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e2a3d128dbf47191393d947a8e96e9
https://europepmc.org/articles/PMC5475248/
https://europepmc.org/articles/PMC5475248/
Publikováno v:
Gene Therapy for Neurological Disorders ISBN: 9781493932702
More than one hundred naturally occurring variants of adeno-associated virus (AAV) have been identified, and this library has been further expanded by an array of techniques for modification of the viral capsid. AAV capsid variants possess unique ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7f824cfd5e5e16ee9cf0f0207f685c
https://doi.org/10.1007/978-1-4939-3271-9_10
https://doi.org/10.1007/978-1-4939-3271-9_10
Autor:
Ru Xiao, Yang Lin, Luk H. Vandenberghe, Heikki Turunen, Eva Plovie-Buys, Rajani Shelke, Simon Pacouret, Eric Zinn
Publikováno v:
Molecular Therapy. 23
Adeno-associated virus (AAV) vectors have emerged as therapy preferred clinical in vivo gene transfer system. Yet, their sensitivity to pre-existing immunity (PEI) and low carrying capacity remain major drawbacks that limit broad applications. We pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c12e7c510573641ad2cc8a6cf6821d
Publikováno v:
Molecular Therapy. 23
Study of naturally occurring isolates of adeno-associated virus has revealed a wide range of phenotypes across several viral characteristics relevant to gene therapy. These fundamental differences in viral properties such as receptor binding, particl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ccdd23936100acaca0ac8377e6fdd1
Autor:
Maurer Anna Claire, Simon Pacouret, Heikki Turunen, Magalie Penaud-Budloo, Mohammed Bouzelha, Mathieu Mével, Ru Xiao, Luk H. Vandenberghe, Philippe Moullier, Véronique Blouin, Frédéric Broucque, Rajani Shelke, Eduard Ayuso
Publikováno v:
Molecular Therapy. 24:S15
Adeno-associated virus (AAV) vectors have emerged as key clinical candidates for gene therapy. Yet, the efficiency and safety of these 20-25 nm biological nanoparticles remain difficult to harmonize across pre-clinical studies due to the limitations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69fc26b55e901b5851033c15d6d0af1d
https://doi.org/10.1016/s1525-0016(16)32843-x
https://doi.org/10.1016/s1525-0016(16)32843-x