Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Heikki Mikola"'
Autor:
Kristiina Wähälä, Richard Hampl, Heikki Mikola, Oldrich Lapcik, Nawaf Al-Maharik, Elke Brouwers, Rafaëlla L’homme, Herman Adlercreutz
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 84:577-587
We present a method for the determination of the isoflavan equol in plasma and urine. This estrogenic isoflavan, which is formed by the action of the intestinal microflora, may have higher biological activity than its precursor daidzein. High urinary
Autor:
Nawaf Al-Maharik, Rafaëlla L’homme, Elke Brouwers, Herman Adlercreutz, Oldrich Lapcik, Richard Hampl, Heikki Mikola, K. Wähälä
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 81:353-361
We present a method for the determination of the phytoestrogen metabolite O -desmethylangolensin ( O -DMA) in plasma (serum) and in urine. O -DMA is a metabolite of daidzein, which occurs in soybeans. It has been suggested that isoflavones may afford
Publikováno v:
Phytochemistry. 46:1339-1347
The overall net photosynthesis potential of Diapensia lapponica was very low. It was highest at the end of August (11.1 μmol CO 2 (μmol chlorophyll) −1 hr −1 ) and decreased during the autumn and winter, reaching a minimum in February (0.6 μmo
Time-Resolved Fluoroimmunoassay for the Measurement of Androstenone in Porcine Serum and Fat Samples
Publikováno v:
Journal of Agricultural and Food Chemistry. 45:3529-3534
A simple competitive time-resolved fluoroimmunoassay was developed for the analysis of the boar taint steroid 5α-androst-16-en-3-one in serum and fat samples. Sensitivities of 30 ng/g and 0.8 ng/mL were obtained for fat and serum measurements, and t
Publikováno v:
Bioconjugate Chemistry. 6:235-241
Lanthanide chelate labels containing substituted 4-(arylethynyl)pyridine as the chromogenic moiety and iminobis(acetic acid) groups as the chelating part were synthesized. N-Succinimidyl esters of the carboxy derivatives of thyroxine and progesterone
Autor:
Heikki Mikola, Elisabeth Hedlöf
Publikováno v:
Steroids. 59:472-478
A simple and efficient method of derivatizing and labeling the terminal sugar ring of digoxin (and other steroid glycosides) is described. The terminal sugar ring was oxidized by periodate to dialdehyde, followed by a reaction with the aminooxy group
Publikováno v:
Bioconjugate Chemistry. 5:278-282
Two different kinds of europium(III) chelates, luminescent and nonluminescent, were prepared. The chelates were coupled to bioanalytical reagents, such as antibodies, after activations of the amino group on the chelates with thiophosgene,2,4,6-trichl
Autor:
James S. Kesner, Mohamed M. Gani, Georff Barnard, Heikki Mikola, Fortune Kohen, Edwin A. Knecht, Edward F. Krieg, John Coley
Publikováno v:
Steroids. 59:205-211
Competitive time-resolved fluoroimmunoassays (FIAs) were developed for measuring 1,3,5(10)-estratrien-3-ol-17-one glucosiduronate (estrone 3-glucuronide, E(1)3G) and 5 beta-Pregnane-3 alpha,20 alpha-diol 3-glucosiduronate (pregnanediol 3-glucuronide,
Publikováno v:
Steroids. 58:330-334
O-Carboxymethyl-, O-(4-aminobutyl)-, and O-(6-aminohexyl)-oximes of 6-oxoestradiol and testosterone were labeled using a described general labeling method with a europium chelate. A stable amide or thiourea bond was formed between the europium label
Publikováno v:
Clinical Chemistry. 38:2038-2043
We describe a quadruple-label fluorometric immunoassay for simultaneously measuring four analytes: thyroid-stimulating hormone (TSH), 17 alpha-hydroxyprogesterone (17 alpha-OHP), immunoreactive trypsin (IRT), and creatine kinase MM (CK-MM). The assay