Výsledky vyhledávání - "Heikki Mikkolainen"

Akademický článek

Concerted regulation of npc2 binding to endosomal/lysosomal membranes by bis(monoacylglycero)phosphate and sphingomyelin.

Autor: Giray Enkavi, Heikki Mikkolainen, Burçin Güngör, Elina Ikonen, Ilpo Vattulainen

Publikováno v: PLoS Computational Biology, Vol 13, Iss 10, p e1005831 (2017)

Niemann-Pick Protein C2 (npc2) is a small soluble protein critical for cholesterol transport within and from the lysosome and the late endosome. Intriguingly, npc2-mediated cholesterol transport has been shown to be modulated by lipids, yet the molec

Externí odkaz: https://doaj.org/article/4ca23a2bc3634b4baf25537d23d04620

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Tail-Oxidized Cholesterol Enhances Membrane Permeability for Small Solutes

Autor: Martin Hof, Ilpo Vattulainen, Piotr Jurkiewicz, Heikki Mikkolainen, Tomasz Róg, Waldemar Kulig, Lukasz Cwiklik, Agnieszka Olżyńska, Pavel Jungwirth, Tomasz Czerniak

Publikováno v: Langmuir

Cholesterol renders mammalian cell membranes more compact by reducing the amount of voids in the membrane structure. Because of this, cholesterol is known to regulate the ability of cell membranes to prevent the permeation of water and water-soluble

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0227137807768da351ac797e1e6d43
https://pubmed.ncbi.nlm.nih.gov/32804507

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Bobbing of Oxysterols: Molecular Mechanism for Translocation of Tail-Oxidized Sterols through Biological Membranes

Autor: Ilpo Vattulainen, Piotr Jurkiewicz, Agnieszka Olżyńska, Heikki Mikkolainen, Waldemar Kulig, Tomasz Róg, Lukasz Cwiklik, Martin Hof, Pavel Jungwirth

Publikováno v: The Journal of Physical Chemistry Letters. 9:1118-1123

Translocation of sterols between cellular membrane leaflets is of key importance in membrane organization, dynamics, and signaling. We present a novel translocation mechanism that differs in a unique manner from the established ones. The bobbing mech

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339c9692eafc1af47fa089cd40935105
https://doi.org/10.1021/acs.jpclett.8b00211

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Concerted regulation of npc2 binding to endosomal/lysosomal membranes by bis(monoacylglycero)phosphate and sphingomyelin

Autor: Elina Ikonen, Heikki Mikkolainen, Giray Enkavi, Ilpo Vattulainen, Burcin Gungor

Publikováno v: Enkavi, G, Mikkolainen, H, Güngör, B, Ikonen, E & Vattulainen, I 2017, ' Concerted regulation of npc2 binding to endosomal/lysosomal membranes by bis(monoacylglycero)phosphate and sphingomyelin ', PLoS Computational Biology, vol. 13, no. 10, e1005831 . https://doi.org/10.1371/journal.pcbi.1005831
PLoS Computational Biology, Vol 13, Iss 10, p e1005831 (2017)
PLoS Computational Biology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f9ea6329c026076a2bd8b7bbad0577
https://findresearcher.sdu.dk:8443/ws/files/136343866/Concerted_regulation_of_npc2_binding_to_endosomal....pdf