Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Heikki, Irjala"'
Autor:
Linda Nissi, Sanni Tuominen, Johannes Routila, Teemu Huusko, Petra Ketonen, Maria Sundvall, Ilmo Leivo, Heikki Irjala, Heikki Minn, Tove J. Grönroos, Sami Ventelä
Publikováno v:
Cancer Medicine, Vol 13, Iss 21, Pp n/a-n/a (2024)
ABSTRACT Background xCT, also known as SLC7A11 (solute carrier Family 7 Member 11), is a cystine/glutamate antiporter protein that mediates regulated cell death and antioxidant defense. The aim of this study was to investigate the effect of xCT on th
Externí odkaz:
https://doaj.org/article/eb07ca8478a24ba99fc48fb427fd5f96
Autor:
Markus Atula, Timo Atula, Katri Aro, Heikki Irjala, Elina Halme, Anna Jouppila-Mättö, Petri Koivunen, Tommy Wilkman, Antti Mäkitie, Marko Elovainio, Laura Pulkki-Råback
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Psychosocial factors and socioeconomic status have been associated with incidence, survival, and quality of life among patients with head and neck cancer. We investigated the association between different psychosocial factors, soc
Externí odkaz:
https://doaj.org/article/53f0923a91324a2b94e192206d2afad5
Autor:
Noora Lehtinen, Janne Suhonen, Kiesha Rice, Eetu Välimäki, Mervi Toriseva, Johannes Routila, Perttu Halme, Melissa Rahi, Heikki Irjala, Ilmo Leivo, Markku Kallajoki, Matthias Nees, Teijo Kuopio, Sami Ventelä, Juha K. Rantala
Publikováno v:
Translational Oncology, Vol 44, Iss , Pp 101935- (2024)
Malignant tumors derived from the epithelium lining the nasal cavity region are termed sinonasal cancers, a highly heterogeneous group of rare tumors accounting for 3 – 5 % of all head and neck cancers. Progress with next-generation molecular profi
Externí odkaz:
https://doaj.org/article/1043b19b0c8148dc8cfad7e1e4daf8d5
Autor:
Aini Hyytiäinen, Katja Korelin, Mervi Toriseva, Tommy Wilkman, Satu Kainulainen, Karri Mesimäki, Johannes Routila, Sami Ventelä, Heikki Irjala, Matthias Nees, Ahmed Al-Samadi, Tuula Salo
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-22 (2023)
Abstract Objective Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive tumor with a 5-year mortality rate of ~ 50%. New in vitro methods are needed for testing patients’ cancer cell response to anti-cancer treatments. We aimed to i
Externí odkaz:
https://doaj.org/article/c23305f8303945c3bb4173ddd2f38bea
Autor:
Sanni Tuominen, Linda Nissi, Antti Kukkula, Johannes Routila, Teemu Huusko, Ilmo Leivo, Heikki Minn, Heikki Irjala, Eliisa Löyttyniemi, Sami Ventelä, Maria Sundvall, Tove J. Grönroos
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundTreatment resistance and relapse are common problems in head and neck squamous cell carcinoma (HNSCC). Except for p16, no clinically accepted prognostic biomarkers are available for HNSCC. New biomarkers predictive of recurrence and surviva
Externí odkaz:
https://doaj.org/article/e593201e187a47768d76a1ee1ab78441
Autor:
Jussi Hirvonen, Jaakko Heikkinen, Mikko Nyman, Tatu Happonen, Jarno Velhonoja, Heikki Irjala, Tero Soukka, Kimmo Mattila, Janne Nurminen
Publikováno v:
Insights into Imaging, Vol 14, Iss 1, Pp 1-31 (2023)
Key points MRI of acute neck infections is feasible in most patients. Most common types are pharyngotonsillar and odontogenic infections. MRI has high diagnostic accuracy for abscesses in adults and children. MRI shows reproducible edema patterns tha
Externí odkaz:
https://doaj.org/article/4b18afbca6694774b8fd834e2e3f20cc
Autor:
Pihla Ranta, Eero Kytö, Linda Nissi, Ilpo Kinnunen, Tero Vahlberg, Heikki Minn, Eeva Haapio, Lassi Nelimarkka, Heikki Irjala
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 7, Iss 1, Pp 108-116 (2022)
Abstract Objectives To analyze the long‐term side effects of radiation therapy (RT) for head and neck cancer (HNC). Methods Retrospective chart analysis of all 688 HNC patients treated during 2010–2015 at Turku University Hospital, Finland. All p
Externí odkaz:
https://doaj.org/article/37ab72b4e4094d31ad6c8e4b262ea32d
Autor:
Janne Nurminen, Jaakko Heikkinen, Tatu Happonen, Mikko Nyman, Aapo Sirén, Jari-Pekka Vierula, Jarno Velhonoja, Heikki Irjala, Tero Soukka, Lauri Ivaska, Kimmo Mattila, Jussi Hirvonen
Publikováno v:
Children, Vol 10, Iss 6, p 967 (2023)
Pediatric neck infections and their complications, such as abscesses extending to deep neck compartments, are potentially life-threatening acute conditions. Medical imaging aims to verify abscesses and their extensions and exclude other complications
Externí odkaz:
https://doaj.org/article/74748f59029e4ac0a6bc44d8d04e3ca8
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 27, Iss , Pp 139-146 (2021)
Background: Locoregional recurrence remains a major cause of failure in head and neck squamous cell carcinoma (HNSCC). Human papilloma virus (HPV)-associated HNSCCs generally have a good prognosis but may recur even after standard photon radiotherapy
Externí odkaz:
https://doaj.org/article/64ac3cd353c24e1781f90587e9ab3010
Autor:
Miia Ruuskanen, Ilmo Leivo, Heikki Minn, Tero Vahlberg, Caj Haglund, Jaana Hagström, Heikki Irjala
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Nasopharyngeal carcinoma (NPC) is a malignant disease with an enigmatic etiology. NPC associates with Epstein-Barr virus (EBV) and human papillomaviruses (HPVs), while immunological factors also play a role in carcinogenesis. Toll
Externí odkaz:
https://doaj.org/article/025ae26a91934e61a36d4a9b012df933