Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Heike Runge"'
Publikováno v:
American Journal of Physiology-Cell Physiology. 304:C128-C136
Myogenic differentiation of skeletal muscle cells is characterized by a sequence of events that include activation of signal transducer and activator of transcription 3 (STAT3) and enhanced expression of its target gene Socs3. Autocrine effects of IL
Publikováno v:
Journal of Cardiovascular Pharmacology. 41:422-433
Statins exert pleiotropic effects on several other cellular functions besides lipid-lowering. Previously, it was found that cerivastatin is a very potent inhibitor of human arterial smooth muscle cell (haSMC) growth. However, because increased extrac
Publikováno v:
Journal of Cardiovascular Pharmacology. 35:619-629
Summary: Statins competitively inhibit 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase activity reducing mevalonate synthesis. In this study, antiproliferative and antimigratory effects of the new compound cerivastatin were analyzed and com
Autor:
Jens Bangsbo, Karl R. Karsch, David J. Grieve, Heike Runge, Daniel A. Beard, Henning Langberg, Ioakim Spyridopoulos, Friederike Neumann, Rudolf Karch, Ulrik Frandsen, Thérèse Keravis, Martin Neumann, Michael Avella, James M. Ritter, Claire Lugnier, Kathleen M. Botham, Jonathan Elliott, Narcisse Komas, M Dawes, Wolfgang Schreiner, Ylva Hellsten, Reimer Riessen, R. Viebahn, Bengt Saltin, James B. Bassingthwaighte, Dorothea I. Axel
Publikováno v:
Journal of Vascular Research. 37:305-339
Autor:
Karl R. Karsch, Dorothea I. Axel, Reimer Riessen, Heike Runge, Anastasios Athanasiadis, Gerhard Köveker
Publikováno v:
Journal of Molecular and Cellular Cardiology. 29:2967-2978
By releasing growth factors, vascular cells can modulate proliferation and migration of neighboring cells in the arterial wall. Previous histological studies in transfilter cocultures, a culture model aimed to simulate vessel wall architecture, indic
Autor:
Cora Weigert, Ann Kathrin Pohl, Hubert Kalbacher, Hans-Ulrich Häring, Matthias Kron, Rainer Lehmann, Erwin Schleicher, Heike Runge
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 22(12)
Transduction of the insulin signal is mediated by multisite Tyr and Ser/Thr phosphorylation of the insulin receptor substrates (IRSs). Previous studies on the function of single-site phosphorylation, particularly phosphorylation of Ser-302, -307, and
Autor:
Heike Runge, Martina Düfer, Erwin Schleicher, Hans U. Häring, Evaine Debre, Perikles Simon, Katrin Brodbeck, Cora Weigert
Publikováno v:
American journal of physiology. Cell physiology. 293(3)
Skeletal muscle cells have been established as significant producers of IL-6 during exercise. This IL-6 production is discussed as one possible mediator of the beneficial effects of physical activity on glucose and fatty acid metabolism. IL-6 itself
Autor:
Ioakim Spyridopoulos, R. Viebahn, Anatol Frigge, Heike Runge, Jasmin Dittmann, Karl R. Karsch, Reimer Riessen, Dorothea I. Axel
Publikováno v:
Cardiovascular research. 49(4)
Objective: The vitamin-A derivative all- trans retinoic acid (atRA) is a potent regulator of cell growth, differentiation, and matrix formation of various cell types and plays an important role in embryogenesis. However, sparse data are available abo
Autor:
Reimer Riessen, R. Viebahn, Dorothea I. Axel, Ioakim Spyridopoulos, Karl R. Karsch, Heike Runge
Publikováno v:
Journal of vascular research. 37(4)
Human arterial smooth muscle cell (haSMC) proliferation is stimulated by platelet-derived growth factor (PDGF) release of human arterial endothelial cells (haEC) whereas transforming growth factor-β1 (TGF-β1) secretion by haSMC promotes extracellul
Autor:
Heike Runge, Ingrid Zenke, Juergen Hartmann, Christina Diehl, Peter Černoch, Helmut Schlaad, Rona Pitschke, Brigitte Tiersch
Publikováno v:
Soft Matter. 6:3784
The kinetics of the crystallization of thermoresponsive poly(2-isopropyl-2-oxazoline) in water and the time- dependent evolution of the morphology were examined using wide-angle X-ray scattering and conventional and cryogenic scanning electron micros