Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Heike Rohweder"'
Autor:
Marie Rieux, Melanie Alpaugh, Shireen Salem, Alberto Siddu, Martine Saint-Pierre, Hélèna L. Denis, Heike Rohweder, Frank Herrmann, Chantal Bazenet, Steve Lacroix, Francesca Cicchetti
Publikováno v:
Neurobiology of Disease, Vol 187, Iss , Pp 106289- (2023)
Externí odkaz:
https://doaj.org/article/20374c4117494cd5af4a06381e01cf57
Autor:
Marie Rieux, Melanie Alpaugh, Shireen Salem, Alberto Siddu, Martine Saint-Pierre, Hélèna L. Denis, Heike Rohweder, Frank Herrmann, Chantal Bazenet, Steve Lacroix, Francesca Cicchetti
Publikováno v:
Neurobiology of Disease, Vol 180, Iss , Pp 106091- (2023)
In a previous study, we have shown that parabiotic coupling of a knock-in mouse model (zQ175) of Huntington's disease (HD) to wild-type (WT) littermates resulted in a worsening of the normal phenotype as seen by detection of mutant huntingtin protein
Externí odkaz:
https://doaj.org/article/e49ceef186c14eb781f5cade28f1336a
Autor:
Douglas Macdonald, Paul H. Patterson, Mark S. Ladinsky, J. Mario Isas, Adam Sabbaugh, Nitin K. Pandey, Ali Khoshnan, Jung Hyun Yoo, Anjalika Chongtham, Ignacio Munoz-Sanjuan, Ralf Langen, Andreas Weiss, Heike Rohweder, Jan Ko, Wei Li Wu
Publikováno v:
Human molecular genetics. 27(13)
The N-terminal fragments of mutant huntingtin (mHTT) misfold and assemble into oligomers, which ultimately bundle into insoluble fibrils. Conformations unique to various assemblies of mHTT remain unknown. Knowledge on the half-life of various multime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6f45dc45148f86d9ec34715a3d9c0a
https://pubmed.ncbi.nlm.nih.gov/29912367
https://pubmed.ncbi.nlm.nih.gov/29912367