Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Heike Pohla"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundManagement of clear cell renal cell carcinoma (ccRCC) has changed rapidly in recent years with the advent of immune checkpoint inhibitors (ICIs). However, only a limited number of patients can sustainably respond to immune checkpoint inhibi
Externí odkaz:
https://doaj.org/article/16117f6c21bf4419a463007448fdf294
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15955 (2022)
Emerging evidence from research or clinical studies reported that ABCG2 (ATP-binding cassette sub-family G member 2) interrelates with multidrug resistance (MDR) development in cancers. However, no comprehensive pan-cancer analysis is available at pr
Externí odkaz:
https://doaj.org/article/578e9d27797143c4ac8acb2cbb8b5d0e
Publikováno v:
Cancers, Vol 14, Iss 17, p 4200 (2022)
The aim of the study was to develop a new therapeutic strategy to target cancer stem cells (CSCs) in clear cell renal cell carcinoma (ccRCC) and to identify typical CSC markers to improve therapy effectiveness. It was found that the corrected-mRNA ex
Externí odkaz:
https://doaj.org/article/a61fc6bd75c94a4a8a4a161a481d524f
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Organ transplantation remains the most effective treatment for patients with late stage organ failure. Transgenic pigs provide an alternative organ donor source to the limited availability of human organs. However, cellular rejection still r
Externí odkaz:
https://doaj.org/article/7fbf1c589ce943f3a4e6124b4af9f078
Autor:
Maxim Werner, Chen Lyu, Birgit Stadlbauer, Isabel Schrader, Alexander Buchner, Herbert Stepp, Ronald Sroka, Heike Pohla
Publikováno v:
Photodiagnosis and Photodynamic Therapy. 39:102987
Glioblastoma multiforme is a malignant neoplasia with a median survival of less than two years and without satisfactory therapeutic options. The so-called glioblastoma stem cells escape the established radio- and chemotherapies and lead to tumor recu
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2021 (2021)
BioMed Research International, Vol 2021 (2021)
Introduction. It has been shown that miR-192 is abnormally expressed in a variety of cancer types and participates in different kinds of signaling pathways. The role of miR-192 in the diagnosis and prognosis of cancer has not been verified. This arti
Publikováno v:
Am J Cancer Res
Cancer stem cells (CSCs) are a small population among cancer cells, defined as capable of self-renewal, and driving tumor growth, metastasis, and therapeutic relapse. The development of therapeutic strategies to target CSCs is of great importance to
Background: Cancer stem cells (CSCs) are a small population among cancer cells, defined as capable of self-renewal, and driving tumor growth, metastasis, and therapeutic relapse. The development of therapeutic strategies to target CSCs is of great im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c6abe1d66e63ec0fb61cd7ae8264359
https://doi.org/10.21203/rs.3.rs-58823/v1
https://doi.org/10.21203/rs.3.rs-58823/v1
Autor:
Adrian Rühm, Herbert Stepp, Odrun A. Gederaas, Xiuli Wang, Wolfgang Zimmermann, Alexander Buchner, Ronald Sroka, Heike Pohla, Thomas Pongratz, Lei Shi, Linglin Zhang
Publikováno v:
Photodiagnosis and photodynamic therapy. 30
Methadone, as a long-acting opioid analgesic, shows an ability to sensitize the treatment of ALA-PDT for glioblastoma cells (A172) in vitro by promoting apoptosis. However, the mechanisms how methadone enhances the effectiveness of ALA-PDT for tumor
Autor:
Christian Homann, Ronald Sroka, Max Eisel, Nikolas Dominik, Thomas Pongratz, Thomas Kellerer, Robert Kammerer, Anna Esipova, Georg Hennig, Niklas Markwardt, Wolfgang Zimmermann, Adrian Ruehm, Alexander Lang, Stephan Ströbl, Claus-Georg Schmedt, Christian Heckl, Heike Pohla, Nicolas Hoehne, Herbert Stepp, Keerthanan Ulaganathan, Christian Freymüller
Publikováno v:
Frontiers of Optoelectronics. 10:239-254
Biophotonics and laser medicine are very dynamic and continuously increasing fields ecologically as well as economically. Direct communication with medical doctors is necessary to identify specific requests and unmet needs. Information on innovative,