Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Heike Merget-Millitzer"'
Autor:
Martin Engelstädter, Heike Merget-Millitzer, RA Willemsen, Stefanie Steidl, Maria Bobkova, Klaus Cichutek, Christian J. Buchholz, Jörn Stitz
Publikováno v:
Gene Therapy. 8:1202-1206
In contrast to murine leukaemia virus (MLV)-derived vector systems, vector particles derived from the avian spleen necrosis virus (SNV) have been successfully targeted to subsets of human cells by envelope modification with antibody fragments (scFv).
Autor:
Martin Engelstädter, Renate König, Frank Nocken, Maria Bobkova, Christian J. Buchholz, Jörn Stitz, Peter Müller, Isabel Schmitt, Stefanie Steidl, Heike Merget-Millitzer, Klaus Cichutek, Reinhard Kurth
Publikováno v:
Virology. 267:229-236
Retroviral vectors derived from amphotropic murine leukemia viruses (MLV) mediate gene transfer into almost all human cells and are thus not suitable for in vivo applications in gene therapy in which cell-specific gene delivery is required. We and ot
Autor:
Frank Nocken, Martin Engelstädter, Reinhard Kurth, Jörn Stitz, Klaus Cichutek, Heike Merget-Millitzer, Barbara S. Schnierle, Valerie Bosch, Bernd Groner
Publikováno v:
Proceedings of the National Academy of Sciences. 94:8640-8645
CD4-expressing T cells in lymphoid organs are infected by the primary strains of HIV and represent one of the main sources of virus replication. Gene therapy strategies are being developed that allow the transfer of exogenous genes into CD4 + T lymph
Autor:
Marion-Gabriele Ott, Hans Martin, Dieter Hoelzer, Oliver G. Ottmann, Manuel Grez, Heike Bialek, Heike Merget-Millitzer, Reinhard Seger, Johann Peter Hossle, Nicole Brüggenolte
Publikováno v:
Journal of hematotherapystem cell research. 11(4)
As a single-gene defect in phagocytes, the X-linked form of chronic granulomatous disease (X-CGD) is a disorder potentially amenable to gene therapy by transfer of a functional copy of the gp91(phox) gene into hematopoietic stem cells (HSC). Although
Publikováno v:
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz; Dec2001, Vol. 44 Issue 12, p1226-1226, 1p