Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Heike Lindenmaier"'
Publikováno v:
Drug Metabolism and Disposition. 35:340-344
Many drug interactions with drugs used for the therapy of human immunodeficiency virus (HIV) occur at the level of different cytochrome P450 isozymes. Increasing evidence suggests that antiretrovirals may also modify activity and expression of active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::790992a0e4f15c7b2c97524fce357a8d
https://doi.org/10.1124/dmd.106.012765
https://doi.org/10.1124/dmd.106.012765
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 372:291-299
Monastrol is the first characterised small molecule inhibitor of the motor protein Eg5 involved in bipolar mitotic spindle assembly. Eg5 localises to microtubules in mitosis, but not to interphase microtubules, suggesting that Eg5 inhibitors may be u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c525e0213f605d09af9569adae889d5b
https://doi.org/10.1007/s00210-005-0022-5
https://doi.org/10.1007/s00210-005-0022-5
Publikováno v:
Molecular Pharmacology. 66:1332-1339
The drug transporter P-glycoprotein (ABCB1) plays an important role in drug distribution and elimination, and when overexpressed it may confer multidrug resistance (MDR). P-glycoprotein is localized in the plasma membrane, especially within rafts and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::334609f0245c805fd63763bfbd415180
https://doi.org/10.1124/mol.104.002329
https://doi.org/10.1124/mol.104.002329
Autor:
Heike Lindenmaier, Johanna Weiss, Tomas Cihlar, Jens Rengelshausen, Walter E. Haefeli, Ingeborg Walter-Sack
Publikováno v:
Biochemical and Biophysical Research Communications. 320:90-94
Caffeine (1,3,7-trimethylxanthine) is daily and widely consumed in beverages and food and is mainly metabolized to 1,7-dimethylxanthine and 1-methylxanthine. Indirect clinical evidence suggests that 1-methylxanthine interacts with the organic anion t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f8bd8cf61dd2de145acb2ee798a082e
https://doi.org/10.1016/j.bbrc.2004.05.142
https://doi.org/10.1016/j.bbrc.2004.05.142
Autor:
Arne Warth, Hendrik Dienemann, Albrecht Stenzinger, Peter Schirmacher, Michael Thomas, Benjamin Goeppert, Hans Hoffmann, Esther Herpel, Philipp A. Schnabel, Heike Lindenmaier, Regine Brandt, Wilko Weichert, Roland Penzel, Thomas Muley, Felix J.F. Herth
Publikováno v:
The European respiratory journal. 43(3)
Numerous studies have been published on single aspects of pulmonary adenocarcinoma (ADC). To comprehensively link clinically relevant ADC characteristics, we evaluated established morphological, diagnostic and predictive biomarkers in 425 resected AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83e14f4ce0314b558376c24ef906e69
https://pubmed.ncbi.nlm.nih.gov/23988776
https://pubmed.ncbi.nlm.nih.gov/23988776
Autor:
F Ulrich, Nina Waldburger, Peter Schirmacher, Wolf O. Bechstein, Thomas Longerich, F Schulze, Heike Lindenmaier, Nils Habbe
Publikováno v:
Gastroenterologie up2date. 10:77-78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::753e3ca9abf326615249cc71736319d9
https://doi.org/10.1055/s-0034-1365803
https://doi.org/10.1055/s-0034-1365803
Publikováno v:
Biochemical pharmacology. 73(10)
Human immunodeficiency virus 1 (HIV-1) infections are treated with HIV-protease inhibitors (PIs), nucleoside (NRTIs), non-nucleoside (NNRTIs), and nucleotide reverse transcriptase inhibitors (NtRTIs). The combined administration of antiretrovirals im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212f00b166eac58d4d76048f4724179b
https://pubmed.ncbi.nlm.nih.gov/17328866
https://pubmed.ncbi.nlm.nih.gov/17328866
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 33(11)
Progestins are widely used as oral contraceptives and hormone replacement therapy. Recently it has been demonstrated that many progestins are inhibitors of P-glycoprotein, possibly explaining gender differences in drug actions. In vitro evidence sugg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0dc2b13da0d54f6f40cf540d4f05498
https://pubmed.ncbi.nlm.nih.gov/16049127
https://pubmed.ncbi.nlm.nih.gov/16049127
Autor:
Verena Schneider, Jens Rengelshausen, Yorki Tayrouz, Heike Lindenmaier, Verena Bergk, Nahal Ketabi-Kiyanvash, Walter E. Haefeli, Meret Martin-Facklam
Publikováno v:
European journal of clinical pharmacology. 60(11)
An important information source for pharmacotherapy in populations at risk is drug labelling. We compared the recommendations for patients with renal insufficiency included in German drug labellings with evidence from the literature.From the 120 drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c24ff4f0c9747bf51ed74170dddbbf
https://pubmed.ncbi.nlm.nih.gov/15599503
https://pubmed.ncbi.nlm.nih.gov/15599503
Publikováno v:
Biochemical pharmacology. 67(2)
Statin/fibrate combinations are frequently used to treat mixed dyslipidemia. However, these combinations may cause life-threatening drug interactions (e.g. rhabdomyolysis) possibly induced by modifications of cytochrome P450 isozyme activities. Some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0982cd83492c210beaf389e396fe5356
https://pubmed.ncbi.nlm.nih.gov/14698041
https://pubmed.ncbi.nlm.nih.gov/14698041