Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Heike Laue"'
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 1002-1007 (2021)
Benzyl salicylate (BS) is a natural ingredient of essential oils and a widely used fragrance chemical. A number of in vitro screening studies have evaluated the estrogenic potential of BS with ambiguous results. Lack of dose-response information for
Externí odkaz:
https://doaj.org/article/58546729d6e241fd997292d5c2249fb8
Publikováno v:
CHIMIA, Vol 74, Iss 3, Pp 168-175 (2020)
The determination of persistence (P), bioaccumulation (B) and toxicity (T) plays a central role in the environmental assessment of chemicals. Persistence is typically evaluated via standard microbial biodegradation tests. Bioaccumulation refers to th
Externí odkaz:
https://doaj.org/article/c06593e9c8854cd58779eb1eaa26a83d
Autor:
Heike Laue
Publikováno v:
VDI-Z. 164:34-36
Die Bearbeitung maßgeschneiderter Werkstoffe aus Nichteisen (NE)-Metallen ist das Spezialgebiet eines modernen Fertigungsbetriebs aus der Klingenstadt Solingen. Seitdem vor Kurzem ein Werkzeugeinstellgerät integriert wurde, laufen alle Prozesse sch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d75b6df204ea99944ead4af9aa0b6bb0
https://doi.org/10.37544/0042-1766-2022-06-34
https://doi.org/10.37544/0042-1766-2022-06-34
Autor:
Lars Hareng, Paul Schuster, Volker Haake, Tilman Walk, Michael Herold, Heike Laue, Andreas Natsch
Publikováno v:
Archives of toxicology. 97(1)
Molecules metabolized to para-tert-butyl-benzoic acid (p-TBBA) affect male reproduction in rats through effects on spermatogenesis. This toxicity is specific to p-TBBA and not observed in meta-substituted analogues. The underlying mode of action was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa09b6599c2697994100f794c924ad99
https://pubmed.ncbi.nlm.nih.gov/36173422
https://pubmed.ncbi.nlm.nih.gov/36173422
Autor:
Lu Hostettler, Jon A. Arnot, Gordon Sanders, Andreas Natsch, Karen J. Jenner, Heike Laue, Remo P. Badertscher
Publikováno v:
Environmental Science & Technology. 54:9483-9494
In vitro biotransformation rates were determined for 30 chemicals, mostly fragrance ingredients, using trout liver S9 fractions (RT-S9) and incorporated into in vitro-in vivo extrapolation (IVIVE) models to predict bioconcentration factors (BCFs). Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb59adf6da0b9a651ac04ee1230824d
https://doi.org/10.1021/acs.est.0c01492
https://doi.org/10.1021/acs.est.0c01492
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 153
Cyclamen aldehyde (CA; 3-(4-isopropylphenyl)-2-methylpropanal) is a widely used fragrance material. Repeated dose studies in rats revealed adverse effects on sperm maturation. Here we review all the mechanistic and in vivo evidence, to determine rele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f628c9470465a088d2789d429e7463d
https://pubmed.ncbi.nlm.nih.gov/33930481
https://pubmed.ncbi.nlm.nih.gov/33930481
Autor:
Adrian Nordone, Lu Hostettler, Andreas Natsch, Remo P. Badertscher, Gregory M. Adamson, Heike Laue, Yumiko Weiner-Sekiya, Tina Haupt
Publikováno v:
Archives of toxicology. 94(12)
A number of para-substituted benzoic acids (p-BA) and chemicals metabolized to p-BA have been found to confer adverse effects in male rats on sperm viability, motility, and morphology. These effects are putatively associated with the metabolism of p-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6082b858d321802b9af99cdceb3017b4
https://pubmed.ncbi.nlm.nih.gov/33057782
https://pubmed.ncbi.nlm.nih.gov/33057782
Publikováno v:
Environmental Toxicology and Chemistry. 37:931-941
Testing for acute fish toxicity is an integral part of the environmental safety assessment of chemicals. A true replacement of primary fish tissue was recently proposed using cell viability in a fish gill cell line (RTgill-W1) as a means of predictin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7270d5815bfd799e6b3fffe73cbf5aea
https://doi.org/10.1002/etc.4027
https://doi.org/10.1002/etc.4027
Publikováno v:
Toxicological Sciences. 160:244-255
Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch) Several aromatic aldehydes such as 3-(4-tert-butylphenyl)-2-methylpropanal were shown to adversely affect the reproductive system in male rats following oral gavage do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e31ae54c5d909c1c4833a2be59524bf
https://doi.org/10.1093/toxsci/kfx178
https://doi.org/10.1093/toxsci/kfx178
Publikováno v:
CHIMIA, Vol 74, Iss 3, Pp 168-175 (2020)
The determination of persistence (P), bioaccumulation (B) and toxicity (T) plays a central role in the environmental assessment of chemicals. Persistence is typically evaluated via standard microbial biodegradation tests. Bioaccumulation refers to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129049d9d2c6c8e639b4c808de6257a9
https://doi.org/10.2533/chimia.2020.168
https://doi.org/10.2533/chimia.2020.168