Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Heike Deisemann"'
Autor:
Wienke Lange, Tianbo Li, Jun Chen, Eleonora Gianti, Elisia Villemure, Matthew Volgraf, Elisa Ballini, Steven Magnuson, Heike Deisemann, Tania Chernov-Rogan, Stuart Ward, Chang Liu, Andrew Peter Cridland, Vincenzo Carnevale, Xiaoyu Hu, Brian Safina, Michael L. Klein, David H. Hackos
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The TRPA1 channel functions as an irritant sensor and is a therapeutic target for treating pain, itch, and respiratory diseases. TRPA1 can be activated by electrophilic compounds via covalent modification or activated by noncovalent agon
Autor:
Amyaouch Bradaia, Heike Deisemann, Larry Park, Simon Gelman, Esther Steidl, Melanie Gleyzes, Ulrike Dijkman, Celia Dominguez, Leticia Toledo-Sherman, Vinod Khetarpal, Outi Kontkanen, Dirk Winkler, Ioana Neagoe, Robert Freije, Mariette Heins, Taneli Heikkinen, Jukka Puoliväli, Robyn M. Javier, Ladislav Mrzljak, Vahri Beaumont, Geoffrey Tombaugh, Kimmo Lehtimäki, Arash Rassoulpour, Ignacio Munoz-Sanjuan, Andreas Ebneth
Publikováno v:
Experimental neurology. 282
Dysregulation of the kynurenine (Kyn) pathway has been associated with the progression of Huntington's disease (HD). In particular, elevated levels of the kynurenine metabolites 3-hydroxy kynurenine (3-OH-Kyn) and quinolinic acid (Quin), have been re
Autor:
Rainer Netzer, Nadine Ahrens, Irene Schlobohm, Clemens Möller, Christian Kirchhoff, Heike Deisemann
Publikováno v:
Journal of cardiovascular pharmacology. 52(6)
A common over-the-counter (OTC) non-opioid antitussive drug, clobutinol, was recently withdrawn from the market due to its potential to induce cardiac arrhythmias by a blockade of the potassium channel coded by the human ether-a-go-go-related gene (h