Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Heike Dally"'
Autor:
Gerd Horneff, Julia Borchert, Joanna Diesing, Pascal Klaus, Ria Heinrich, Heike Dally, Christine Hagemann, Simon Kock, Tonio Schönfelder
Publikováno v:
Life, Vol 14, Iss 6, p 712 (2024)
(1) Background: Achieving inactive disease decreases long-term joint damage in patients with polyarticular juvenile idiopathic arthritis (polyJIA). The aim of our study was to describe average time to treatment and medication changes over time. (2) M
Externí odkaz:
https://doaj.org/article/e791c46a5d164c588ff7cfb0ae32374b
Autor:
Gerd Horneff, Julia Borchert, Ria Heinrich, Simon Kock, Pascal Klaus, Heike Dally, Christine Hagemann, Joanna Diesing, Tonio Schönfelder
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background Juvenile idiopathic arthritis (JIA) describes heterogenous categories of chronic inflammatory rheumatic conditions of unknown origin in children and adolescents. Epidemiological data in the literature vary, depending on geographic
Externí odkaz:
https://doaj.org/article/faeb7364554d444e9bcc9373fdeb421b
Autor:
Heike Dally
Ist der Goldstandard der Zulassungsstudie, die kontrollierte randomisierte Doppelblindstudie, in der Onkologie noch adäquat? Die therapeutische Behandlung von Patienten mit onkologischen Erkrankungen orientiert sich nicht mehr nur an der Histologie
Autor:
Heike Dally, Lena Franziska Knoefel, Niels Reinmuth, Michael Thomas, Claus Peter Heussel, Lutz Edler, Angela Risch, Helmut Bartsch, Gisela Werle-Schneider, Siegfried Tuengerthal, Phillip Müller
Publikováno v:
Journal of Thoracic Oncology. 6(1):183-189
Introduction: We investigated the single-nucleotide polymorphism C-938A in the apoptotic gene BCL-2 to assess the potential impact as a genetic marker for response to chemotherapy and outcome prediction in small cell lung cancer (SCLC) patients. Such
Autor:
Margaret R. Spitz, Simone Benhamou, Kwun M. Fong, Jill E. Larsen, Nohelia Cajas-Salazar, Ping Yang, Brian G. Weinshenker, Ingolf Cascorbi, Isabelle Stücker, Angela Risch, Loic Le Marchand, Stephanie J. London, C. Bouchardy, Emanuela Taioli, Heike Dally, Xifeng Wu
Publikováno v:
Genetics in Medicine. 9:67-73
Myeloperoxidase is a phase I metabolic enzyme that converts the metabolites of benzo[a]pyrene from tobacco smoke into highly reactive epoxides. A polymorphism in the promoter region of myeloperoxidase (463G-->A) has been found to be inversely associa
Autor:
Lutz Edler, Heike Dally, Klaus Kayser, Angela Risch, Birgit Jäger, Peter Schmezer, Helmut Bartsch, Peter Drings, Volker Schulz, Hendrik Dienemann, Bertold Spiegelhalder
Publikováno v:
Cancer Letters. 207:95-99
Genetic polymorphisms of the human CYP3A family affect clinical drug efficacy and may modify cancer risk. CYP3A genes show high sequence similarity that had previously lead to misallocation of CYP3A polymorphisms. Recent studies indicated a high degr
Autor:
Helmut Bartsch, Klaus Kayser, Kai Gassner, Heike Dally, Peter Drings, Volker Schulz, Peter Schmezer, Hendrik Dienemann, Bertold Spiegelhalder, Lutz Edler, Angela Risch, Birgit Jäger
Publikováno v:
International Journal of Cancer. 102:530-535
MPO participates in the metabolic activation of tobacco carcinogens such as PAHs. A frequent MPO −463 GA polymorphism in the promoter region reduces MPO transcription and has been correlated with >4-fold lower benzo[a]pyrene–DNA adduct levels in
Publikováno v:
Fresenius' Journal of Analytical Chemistry. 361:377-380
Based on pronounced enhancing effects in combination with other DNA-damaging agents the potentials of Ni(II), Cd(II) and As(III) to interfere with DNA repair processes in HeLa cells was investigated. With respect to oxidative DNA damage, Ni(II) and C
Autor:
Andrea Hartwig, Heike Dally
Publikováno v:
Carcinogenesis. 18:1021-1026
Compounds of nickel(II) and cadmium(II) are carcinogenic to humans and to experimental animals. One frequently discussed mechanism involved in tumor formation is an increase in reactive oxygen species by both metals with the subsequent generation of
Autor:
Peter Drings, Jürgen Fischer, Gisela Werle-Schneider, H Bartsch, Siegfried Tuengerthal, Heike Dally, David Scherf, Phillip Müller, Lutz Edler, Angela Risch, Birgit Jäger
Publikováno v:
The European respiratory journal. 35(2)
The prognosis for lung cancer patients treated with chemotherapy is poor. Single nucleotide polymorphisms (SNPs) in matrix metalloproteinase (MMP) genes could influence treatment outcome by altering apoptotic pathways. Eight SNPs with known or suspec