Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Heike Allgayer"'
Autor:
Luigi Marongiu, Heike Allgayer
Publikováno v:
Molecular Oncology, Vol 16, Iss 7, Pp 1423-1450 (2022)
Increasing evidence suggests that microorganisms might represent at least highly interesting cofactors in colorectal cancer (CRC) oncogenesis and progression. Still, associated mechanisms, specifically in colonocytes and their microenvironmental inte
Externí odkaz:
https://doaj.org/article/1bb8a4d71b974d81be1cbc3b20c9d9d9
Autor:
Luigi Marongiu, Jonathan J. M. Landry, Tobias Rausch, Mohammed L. Abba, Susanne Delecluse, Henri‐Jacques Delecluse, Heike Allgayer
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3363-3384 (2021)
The paucity of microbiome studies at intestinal tissues has contributed to a yet limited understanding of potential viral and bacterial cofactors of colorectal cancer (CRC) carcinogenesis or progression. We analysed whole‐genome sequences of CRC pr
Externí odkaz:
https://doaj.org/article/7de803998014476aa150c199a99be616
Autor:
Minakshi Gandhi, Matthias Groß, Jessica M. Holler, Si’Ana A. Coggins, Nitin Patil, Joerg H. Leupold, Mathias Munschauer, Monica Schenone, Christina R. Hartigan, Heike Allgayer, Baek Kim, Sven Diederichs
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Despite some well-characterized functions in cancer, the impact of most long non-coding RNAs remains unknown. Here, the authors discover the lncRNA lincNMR which is upregulated in cancer and drives cell proliferation by interacting with YBX1 and cont
Externí odkaz:
https://doaj.org/article/186c4d276d704b2c8e6ccb57bb201c3b
Publikováno v:
F1000Research, Vol 9 (2021)
Background: Accurate viral load (VL) determination is paramount to determine the efficacy of anti-HIV-1 therapy. The conventional method used, fit-point (FP), assumes an equal efficiency in the polymerase chain reaction (PCR) among samples that might
Externí odkaz:
https://doaj.org/article/c0299df279fe47a1a2e91e6e10d757bf
Autor:
Naveed Ishaque, Mohammed L. Abba, Christine Hauser, Nitin Patil, Nagarajan Paramasivam, Daniel Huebschmann, Jörg Hendrik Leupold, Gnana Prakash Balasubramanian, Kortine Kleinheinz, Umut H. Toprak, Barbara Hutter, Axel Benner, Anna Shavinskaya, Chan Zhou, Zuguang Gu, Jules Kerssemakers, Alexander Marx, Marcin Moniuszko, Miroslaw Kozlowski, Joanna Reszec, Jacek Niklinski, Jürgen Eils, Matthias Schlesner, Roland Eils, Benedikt Brors, Heike Allgayer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The evolution and genetic nature of metastatic lesions is not completely characterized. Here the authors perform a comprehensive whole-genome study of colorectal metastases in comparison to matched primary tumors and define a multistage progression m
Externí odkaz:
https://doaj.org/article/4e68117793d04d9682b7c9652d4393b8
Autor:
Lionel Larribère, Yohanes Cakrapradipta Wibowo, Nitin Patil, Mohammed Abba, Isabel Tundidor, Rubén Gerardo Aguiñón Olivares, Heike Allgayer, Jochen Utikal
Publikováno v:
Translational Oncology, Vol 13, Iss 12, Pp 100858- (2020)
Metastases's spreading is the main cause of mortality for advanced stage cancer patients, including melanoma. The formation of metastases is favored by enhanced migratory and invasive capacities of tumor cells. Tumor suppressor gene NF1 is a negative
Externí odkaz:
https://doaj.org/article/efce6d111dc54224b0018576f447c33c
Publikováno v:
Genomics Data, Vol 6, Iss C, Pp 33-35 (2015)
Tumor metastasis continues to be the most significant contributor to cancer related mortality, and although several studies have examined expression profiles emanating from patients with metastatic disease, very little information is available about
Externí odkaz:
https://doaj.org/article/474db73e24e044e9a8dd2181f57da417
Autor:
Natascha Cremers, Antje Neeb, Tanja Uhle, Arno Dimmler, Melanie Rothley, Heike Allgayer, Riccardo Fodde, Jonathan Paul Sleeman, Wilko Thiele
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151468 (2016)
CD24 is a small, heavily glycosylated, GPI-linked membrane protein, whose expression has been associated with the tumorigenesis and progression of several types of cancer. Here, we studied the expression of CD24 in tumors of MMTV-PyMT, Apc1572/T+ and
Externí odkaz:
https://doaj.org/article/5d17e61772cf44eba61f3f6aebfa4b6d
Publikováno v:
BioTechniques, Vol 37, Iss 6, Pp 940-946 (2004)
The chick embryonic metastasis (CEM) assay is a fast in vivo method to investigate the invasive properties of tumor cells. Until now, most quantification methods were semiquantitative and time-consuming. Here we describe a rapid quantification method
Externí odkaz:
https://doaj.org/article/afa371fefa094f21a6124fd706fc3ffc
Autor:
Santoshi Muppala, Giridhar Mudduluru, Jörg H Leupold, Daniel Buergy, Jonathan P Sleeman, Heike Allgayer
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59563 (2013)
Cancer is a complex disease process that evolves as a consequence of multiple malfunctions in key regulatory molecular networks. Understanding these networks will be essential to combat cancer. In this study, we focussed on central players in such ne
Externí odkaz:
https://doaj.org/article/e4044d4f17184f569fa1b41ec5c232c7