Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Heike, Hirseland"'
Autor:
Axel R. Schulz, Leonard Fiebig, Heike Hirseland, Lisa-Marie Diekmann, Simon Reinke, Sebastian Hardt, Antonia Niedobitek, Henrik E. Mei
Publikováno v:
EBioMedicine, Vol 95, Iss , Pp 104735- (2023)
Summary: Background: SARS-CoV-2 specific antibody-secreting plasma cells (PC) mediating specific humoral immunity have been identified in the human bone marrow (BM) after COVID-19 or vaccination against SARS-CoV-2. However, it remained unclear whethe
Externí odkaz:
https://doaj.org/article/e841c7cf0ba1456ca09588607aa6fba6
Autor:
Ursula Schulte-Wrede, Till Sörensen, Joachim R. Grün, Thomas Häupl, Heike Hirseland, Marta Steinbrich-Zöllner, Peihua Wu, Andreas Radbruch, Denis Poddubnyy, Joachim Sieper, Uta Syrbe, Andreas Grützkau
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-10 (2018)
Abstract Background Therapeutic targeting of tumour necrosis factor (TNF)-α is highly effective in ankylosing spondylitis (AS) patients. However, since one-third of anti-TNF-treated AS patients do not show an adequate clinical response there is an u
Externí odkaz:
https://doaj.org/article/aeef69ba1ab44bfa92b5e78fc618f0e9
Autor:
Axel R. Schulz, Heike Hirseland, Lisa-Marie Diekmann, Simon Reinke, Sebastian Hardt, Antonia Niedobitek, Henrik E. Mei
Establishment of long-lived plasma cells (PC) in the bone marrow (BM) is important for the development of long-term specific humoral immunity. While SARS-CoV-2-specific, resting, affinity-matured, IgG-secreting plasma cells were described in human bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48bd5917cead9c43119e061f6ea5f7fa
https://doi.org/10.1101/2022.08.11.503574
https://doi.org/10.1101/2022.08.11.503574
Autor:
Addi J. Romero-Olmedo, Axel Ronald Schulz, Svenja Hochstätter, Dennis Das Gupta, Heike Hirseland, Daniel Staudenraus, Bärbel Camara, Kirsten Volland, Véronique Hefter, Siddhesh Sapre, Verena Krähling, Helena Müller-Kräuter, Henrik E. Mei, Christian Keller, Michael Lohoff
A third mRNA-based “booster” vaccination is the favored strategy to maintain protection against SARS-CoV-2 infection. Yet, significant waning of specific immunity within six months after 2nd vaccination, along with higher incidence of breakthroug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d8160cd519cec4fc425887a79c9d7b0
https://doi.org/10.1101/2022.02.10.22270733
https://doi.org/10.1101/2022.02.10.22270733
Autor:
Addi J, Romero-Olmedo, Axel Ronald, Schulz, Svenja, Hochstätter, Dennis Das, Gupta, Heike, Hirseland, Daniel, Staudenraus, Bärbel, Camara, Kirsten, Volland, Véronique, Hefter, Siddhesh, Sapre, Verena, Krähling, Helena, Müller-Kräuter, Ho-Ryun, Chung, Henrik E, Mei, Christian, Keller, Michael, Lohoff
Publikováno v:
The Lancet Infectious Diseases. 22:588-589
Autor:
Daniel Staudenraus, Siddhesh Sapre, Iiris Virta, Heike Hirseland, Dennis DasGupta, Axel Schulz, Addi Romero Olmedo, Carina Münch, Svenja Hochstäter, Christian Keller, Bärbel Camara, Michael Lohoff, Henrik E. Mei, Véronique Hefter
Herein, we compared SARS-CoV-2-specific antibody and T-cell responses to two doses of BNT162b2 mRNA in 51 vaccinees > 80 years old and 46 (20–53 years old) controls. The responses of the elderly were much lower and 10% non-responders were identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea26beed0e6f28a9e4efcc7dca41e0b5
https://doi.org/10.21203/rs.3.rs-900790/v1
https://doi.org/10.21203/rs.3.rs-900790/v1
Autor:
Addi J. Romero-Olmedo, Axel Ronald Schulz, Svenja Hochstätter, Dennis Das Gupta, Iiris Virta, Heike Hirseland, Daniel Staudenraus, Bärbel Camara, Carina Münch, Véronique Hefter, Siddhesh Sapre, Verena Krähling, Helena Müller-Kräuter, Marek Widera, Henrik E. Mei, Christian Keller, Michael Lohoff
Publikováno v:
Nature microbiology
Here we compared SARS-CoV-2-specific antibody and T-cell responses between older adults (80 years old, n = 51) and a younger control group (20-53 years old, n = 46) after receiving two doses of BNT162b2. We found that responses in older adults were g
Autor:
Hubert Schäfer, Yury V. Shebzukhov, Andreas Radbruch, Heike Hirseland, Susanne Holtze, Thomas Hildebrandt, Andreas Grützkau
Publikováno v:
European Journal of Immunology
European journal of immunology, 49(11):2103-2110
European journal of immunology, 49(11):2103-2110
The naked mole rat (Heterocephalus glaber, NMR) is a rodent with exceptional longevity, low rates of age‐related diseases and spontaneous carcinogenesis. The NMR represents an attractive animal model in longevity and cancer research, but there are
Autor:
Andreas Grützkau, Susanne Krauthäuser, Silke Stanislawiak, Anette Peddinghaus, Axel Schulz, Sarah Gillert, Henrik E. Mei, Christian Dose, Sabine Baumgart, Heike Hirseland
Publikováno v:
European Journal of Immunology. 47:1377-1385
Antibody conjugates applicable in both conventional flow and mass cytometry would offer interesting options for cross-platform comparison, as well as the enrichment of rare target cells by conventional flow cytometry (FC) sorting prior to deep phenot
Autor:
Andreas Grützkau, Yury V. Shebzukhov, Heike Hirseland, Andreas Radbruch, Hubert Schäfer, Susanne Holtze, Thomas B. Hildebrandt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43fcf0d3965cde5e8332525f77abbd7b
https://doi.org/10.1002/eji.201948124/v4/response1
https://doi.org/10.1002/eji.201948124/v4/response1