Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Heidrun L Deissler"'
Autor:
Johanna M Walz, Daniel Boehringer, Heidrun L Deissler, Lothar Faerber, Jens C Goepfert, Peter Heiduschka, Susannah M Kleeberger, Alexa Klettner, Tim U Krohne, Nicole Schneiderhan-Marra, Focke Ziemssen, Andreas Stahl
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0145375 (2016)
BACKGROUND:Vascular endothelial growth factor-A (VEGF-A) is intensively investigated in various medical fields. However, comparing VEGF-A measurements is difficult because sample acquisition and pre-analytic procedures differ between studies. We ther
Externí odkaz:
https://doaj.org/article/0904857535264bc5802fd72adfbe28c6
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Because rare, but severe adverse effects, i.e. retinal vasculitis or retinal vein occlusion, have been observed after repetitive intravitreal injections of VEGF-A-binding single-chain variable fragment brolucizumab (Beovu), we investigated i
Externí odkaz:
https://doaj.org/article/489b5d3c620344e6953c3e9f9f7f0134
Autor:
Catharina Busch, Matus Rehak, Margrit Hollborn, Peter Wiedemann, Gerhard K. Lang, Gabriele E. Lang, Armin Wolf, Heidrun L. Deissler
Publikováno v:
Heliyon, Vol 7, Iss 1, Pp e06037- (2021)
Contradictory behavior of microvascular retinal endothelial cells (REC) - a reliable in vitro model to study retinal diseases - have recently been reported which might result from cultivating the cells in standard DMEM not optimized for this cell typ
Externí odkaz:
https://doaj.org/article/a1d3b8c65c0542749008b283c0105d77
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 734 (2022)
As responses of immortalized endothelial cells of the bovine retina (iBREC) to VEGF-A165 depend on exposure time to the growth factor, we investigated changes evident after long-term treatment for nine days. The cell index of iBREC cultivated on gold
Externí odkaz:
https://doaj.org/article/98f41524ea654b6a8227ce2be2ac4a95
Autor:
Anja Jäckle, Focke Ziemssen, Eva-Maria Kuhn, Jürgen Kampmeier, Gerhard K. Lang, Gabriele E. Lang, Helmut Deissler, Heidrun L. Deissler
Publikováno v:
Journal of Diabetes Research, Vol 2020 (2020)
Inhibitors of dipeptidyl peptidase-4 (DPP-4) are widely used to treat diabetes mellitus, but data concerning their effects on the barrier stability of retinal endothelial cells (REC) in vivo and in vitro are inconsistent. Therefore, we studied whethe
Externí odkaz:
https://doaj.org/article/15a9a314203046ed9840610926fbff25
Autor:
Heidrun L. Deissler, Matus Rehak
Publikováno v:
Acta Ophthalmologica. 100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aff757b5c9183c1c8f375db9170ebc68
https://doi.org/10.1111/j.1755-3768.2022.15503
https://doi.org/10.1111/j.1755-3768.2022.15503
Autor:
Jürgen Kampmeier, Heidrun L. Deissler, Anja Jäckle, Gabriele E. Lang, Helmut Deissler, Eva-Maria Kuhn, Gerhard K. Lang, Focke Ziemssen
Publikováno v:
Journal of Diabetes Research
Journal of Diabetes Research, Vol 2020 (2020)
Journal of Diabetes Research, Vol 2020 (2020)
Inhibitors of dipeptidyl peptidase-4 (DPP-4) are widely used to treat diabetes mellitus, but data concerning their effects on the barrier stability of retinal endothelial cells (REC) in vivo and in vitro are inconsistent. Therefore, we studied whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9d7986efa42a63dce4a94f00f96232
https://doi.org/10.1155/2020/2450781
https://doi.org/10.1155/2020/2450781
Publikováno v:
Experimental eye research. 216
The VEGF-A-induced functional impairment of the barrier formed by retinal endothelial cells (REC) can be prevented and even - at least temporarily - reverted by trapping the growth factor in a complex with a VEGF-binding protein or by inhibiting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52549701feeac333b886dce4c2a82556
https://pubmed.ncbi.nlm.nih.gov/35038456
https://pubmed.ncbi.nlm.nih.gov/35038456
Publikováno v:
Experimental eye research. 198
Retinal vessels are at least in part involved in clearing of Fc terminus-containing proteins from the vitreous. In vitro, the Fc fusion protein aflibercept is transported through a monolayer of unchallenged immortalized bovine retinal endothelial cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8cfccef44089952d501a9e9272203a5b
https://pubmed.ncbi.nlm.nih.gov/32712182
https://pubmed.ncbi.nlm.nih.gov/32712182
Publikováno v:
Cellular Physiology and Biochemistry, Vol 42, Iss 4, Pp 1493-1513 (2017)
Background/Aims: Hallmark of diabetic macular edema is the enhanced permeability of retinal endothelial cells (REC) induced by vascular endothelial growth factor (VEGF-A165), which acts through activating specific receptors. To improve the predictabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2199e65a0fbfbec47b2076ba947cc630
https://doi.org/10.1159/000479213
https://doi.org/10.1159/000479213