Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Heidi Wallweber"'
Autor:
Kelly M Storek, Joyce Chan, Rajesh Vij, Nancy Chiang, Zhonghua Lin, Jack Bevers III, Christopher M Koth, Jean-Michel Vernes, Y Gloria Meng, JianPing Yin, Heidi Wallweber, Olivier Dalmas, Stephanie Shriver, Christine Tam, Kellen Schneider, Dhaya Seshasayee, Gerald Nakamura, Peter A Smith, Jian Payandeh, James T Koerber, Laetitia Comps-Agrar, Steven T Rutherford
Publikováno v:
eLife, Vol 8 (2019)
Outer membrane proteins (OMPs) in Gram-negative bacteria dictate permeability of metabolites, antibiotics, and toxins. Elucidating the structure-function relationships governing OMPs within native membrane environments remains challenging. We constru
Externí odkaz:
https://doaj.org/article/ce2cff4a5d574858abb6291276ed9aec
Autor:
Emily J. Hanan, Marie-Gabrielle Braun, Robert A. Heald, Calum MacLeod, Connie Chan, Saundra Clausen, Kyle A. Edgar, Charles Eigenbrot, Richard Elliott, Nicholas Endres, Lori S. Friedman, Emily Gogol, Xiao-Hui Gu, Rebecca Hong Thibodeau, Philip S. Jackson, James R. Kiefer, Jamie D. Knight, Michelle Nannini, Raman Narukulla, Amanda Pace, Jodie Pang, Hans E. Purkey, Laurent Salphati, Deepak Sampath, Stephen Schmidt, Steve Sideris, Kyung Song, Swathi Sujatha-Bhaskar, Mark Ultsch, Heidi Wallweber, Jianfeng Xin, SiewKuen Yeap, Amy Young, Yu Zhong, Steven T. Staben
Publikováno v:
Journal of medicinal chemistry. 65(24)
Small molecule inhibitors that target the phosphatidylinositol 3-kinase (PI3K) signaling pathway have received significant interest for the treatment of cancers. The class I isoform PI3Kα is most commonly associated with solid tumors via gene amplif