Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Heidi W Trask"'
Autor:
Kenta Nakamura, Nobuyasu Maki, Albert Trinh, Heidi W Trask, Jiang Gui, Craig R Tomlinson, Panagiotis A Tsonis
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12058 (2010)
Lens regeneration in adult newts occurs via transdifferentiation of the pigment epithelial cells (PECs) of the dorsal iris. The same source of cells from the ventral iris is not able to undergo this process. In an attempt to understand this restricti
Externí odkaz:
https://doaj.org/article/f84ebe01b00f46a2a2a269c5c1726db7
Autor:
Nicholas K. Preiss, Yasmin Kamal, Owen M. Williams, Chenyang Li, Fred W. Kolling, Heidi W. Trask, Young-Kwang Usherwood, Chao Cheng, Hildreth R. Frost, Edward J. Usherwood
Members of the BTB-ZF transcription factor family regulate the immune system. Our lab identified that family member Zbtb20 contributes to the differentiation, recall responses and metabolism of CD8 T cells. Here, we report a characterization of the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a8dd9ccc74c9d006aaa02cacd6e5ed2
https://doi.org/10.1101/2022.08.22.504726
https://doi.org/10.1101/2022.08.22.504726
Autor:
Ananta Bhatt, Todd W. Miller, Jason D. Wells, Nancy J. McNulty, Richard J. Barth, Jennifer R. Bean, Jiang Gui, Mary D. Chamberlin, Wendy A. Wells, Peter A. Kaufman, Jonathan D. Marotti, Michael J. Tsapakos, John M Gemery, Fred W. Kolling, Gary N. Schwartz, Kevin Shee, Bradley A. Arrick, Heidi W. Trask
Publikováno v:
Breast Cancer Res Treat
PURPOSE: Circulating tumor DNA in plasma may present a minimally invasive opportunity to identify tumor-derived mutations to inform selection of targeted therapies for individual patients, particularly in cases of oligometastatic disease where biopsy
Autor:
Haley F. Hazlett, Barjor Gimi, Krishnamurthy V. Nemani, William B. Kinlaw, Leslie E. Lupien, Heidi W. Trask, Alan J. Collins, Itzel Y. Rojas, Rachel J. West, Benjamin J. Moyer, Carol S. Ringelberg, Joanna S. Kerley-Hamilton, Craig R. Tomlinson
Publikováno v:
Toxicology and Applied Pharmacology. 300:13-24
Obesity is an increasingly urgent global problem, yet, little is known about its causes and less is known how obesity can be effectively treated. We showed previously that the aryl hydrocarbon receptor (AHR) plays a role in the regulation of body mas
Autor:
Itzel Y. Rojas, Barjor Gimi, Carol S. Ringelberg, Krishnamurthy V. Nemani, Benjamin J. Moyer, Joanna S. Kerley-Hamilton, Eugene Demidenko, Heidi W. Trask, Craig R. Tomlinson
Inhibition of the aryl hydrocarbon receptor (AHR) prevents Western diet-induced obesity and fatty liver in C57Bl/6J (B6) male mice. The AHR is a ligand-activated nuclear receptor that regulates genes involved in xenobiotic metabolism and T cell diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1820ed1559a7379d1d19b3e82bfa2fb
https://europepmc.org/articles/PMC5569910/
https://europepmc.org/articles/PMC5569910/
Autor:
Heidi W. Trask, Karen L Moodie, Nilufer Nurinova, Diandra Wong, Eric DuFour, Jason H. Moore, Craig R. Tomlinson, Carol S. Ringelberg, Murray Korc, Christian J.A. Ridley, Joanna S. Kerley-Hamilton, Nicholas W. Shworak, Samantha Shipman
Publikováno v:
Environmental Health Perspectives
Background: Obesity is a growing worldwide problem with genetic and environmental causes, and it is an underlying basis for many diseases. Studies have shown that the toxicant-activated aryl hydrocarbon receptor (AHR) may disrupt fat metabolism and c
Autor:
Heidi W. Trask, Peter R. Sinclair, Judith M. Jacobs, Trisha L. Noreault-Conti, Steven A. Wrighton, Stephen C. Strom, Ronald M. Evans, Jacqueline F. Sinclair, Abigail M. Fellows, Ralph C. Nichols
Publikováno v:
International Immunopharmacology. 12:651-656
Arsenite is critical pharmacologically as a treatment for advanced stage blood cancer. However, environmental exposure to arsenic results in multiple diseases. Previous studies have shown that arsenic decreases expression of CYP3A, a critical drug me
Autor:
Heidi W. Trask, John M Gemery, Richard J. Barth, Chamberlin, Kevin Shee, RJ West, Bradley A. Arrick, Todd W. Miller, Jiang Gui, Peter A. Kaufman, Wendy A. Wells, Michael J. Tsapakos, Nancy J. McNulty, Jennifer R. Bean, Jonathan D. Marotti, Gary N. Schwartz, Frederick S. Varn, JS Hamilton, Chao Cheng
Publikováno v:
Cancer Research. 77:P6-07
Background: Circulating tumor DNA in plasma may present a minimally invasive approach to identify tumor-derived mutations that could be used to inform the selection of targeted therapies for individual patients, particularly in cases of metastatic di
Autor:
Sinny Wang, Heidi W. Trask, Murray Korc, Jason H. Moore, Craig R. Tomlinson, Richard C Sallari, Jessica A. Thornley, Carol S. Ringelberg, Christian J.A. Ridley
Publikováno v:
Molecular Carcinogenesis. 51:771-782
Pancreatic cancer is the fourth leading cause of cancer death in the United States because most patients are diagnosed too late in the course of the disease to be treated effectively. Thus, there is a pressing need to more clearly understand how gene
Autor:
Jacqueline F. Sinclair, Trisha L. Noreault, Peter R. Sinclair, Ronald M. Evans, Heidi W. Trask, Steven A. Wrighton, Ralph C. Nichols, Judith M. Jacobs
Publikováno v:
Toxicology and Applied Pharmacology. 209:174-182
Arsenic is a naturally occurring, worldwide contaminant implicated in numerous pathological conditions in humans, including cancer and several forms of liver disease. One of the contributing factors to these disorders may be the alteration of cytochr