Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Heidi Swaim"'
Autor:
Marla D. Swain, Yolanda L. Jones, Heidi Swaim, Xiaolin Wu, Min Zhu, Haile F. Yancy, Michael J. Myers, Yi Ming, Christine M. Deaver
Publikováno v:
American Journal of Veterinary Research. 75:1104-1110
Objective—To identify biomarkers of P-glycoprotein (P-gp) substrate neurotoxicity in transgenic mice expressing the mutant canine ABCB1 gene (ABCB1-1Δ). Animals—8 ABCB1 knock-in and knock-out transgenic mice expressing the ABCB1-1Δ gene and 8 c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47fafbf14487d8f0a519f9e7bf671ce
https://doi.org/10.2460/ajvr.75.12.1104
https://doi.org/10.2460/ajvr.75.12.1104
Autor:
Michael J. Myers, M.D. Swain, Yolanda L. Jones, C.A. Tinaza, M.V. Jhingory, V.A. Lancaster, K.L. Orzechowski, M.G. Robl, Heidi Swaim, Haile F. Yancy, L.E. Buckely
Publikováno v:
Research in Veterinary Science. 94:656-661
Certain dog breeds, especially Collies, are observed to exhibit neurotoxicity to avermectin drugs, which are P-glycoprotein (P-gp) substrates. This neurotoxicity is due to an ABCB1 gene mutation (ABCB1-1Δ) that results in non-functional P-gp express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50bac85ac5da4ad617d749f04a110c82
https://doi.org/10.1016/j.rvsc.2012.10.025
https://doi.org/10.1016/j.rvsc.2012.10.025
Autor:
Michael J. Myers, Krystyna L. Orzechowski, Marla D. Swain, Martin G. Robl, Constante A. Tinaza, Heidi Swaim, Haile F. Yancy, Yolanda L. Jones
Publikováno v:
American Journal of Veterinary Research. 73:1477-1484
Objective—To develop in genetically engineered mice an alternative screening method for evaluation of P-glycoprotein substrate toxicosis in ivermectin-sensitive Collies. Animals—14 wild-type C57BL/6J mice (controls) and 21 genetically engineered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c3cdd5f92c1b3af763a5b29d1f586a0
https://doi.org/10.2460/ajvr.73.9.1477
https://doi.org/10.2460/ajvr.73.9.1477
Autor:
George M. Blackstone, Yolanda L. Jones, Haile F. Yancy, Bill Marion, Tai Ha, Sharla M. Peters, Heidi Swaim, Fabio La Neve, Michael J. Myers, Michael C. L. Vickery, Jason Ekins, Tiziana Civera
Publikováno v:
Journal of Food Protection. 75:1107-1112
The U.S. Food and Drug Administration (FDA) has previously validated a real-time PCR-based assay that is currently being used by the FDA and several state laboratories as the official screening method. Due to several shortcomings to the assay, a mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87662b3c8060007ae5655d6039b37030
https://doi.org/10.4315/0362-028x.jfp-11-415
https://doi.org/10.4315/0362-028x.jfp-11-415
Autor:
Michael J. Myers, Jacquline Mason, Heidi Swaim, Haile F. Yancy, Christine M. Deaver, Dorothy E. Farrell
Publikováno v:
Journal of Food Protection. 73:1090-1096
The capability of eight commercially available DNA extraction kits to extract bovine DNA originating in meat and bone meal from fortified feed was evaluated. Four different batches of bovine meat and bone meal (BMBM) were used for DNA extraction with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511505443632065c1cd5e03ad974f1a6
https://doi.org/10.4315/0362-028x-73.6.1090
https://doi.org/10.4315/0362-028x-73.6.1090
Publikováno v:
The Journal of Immunology. 194:195.3-195.3
Carrageenan-induced inflammation, though extensively used as a model of local inflammation, has not been fully characterized on the genomic and proteomic level. The goal of this study was to develop an in vitro carrageenan model of local inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8b2cccff420302b0eafcbaffe21630b
https://doi.org/10.4049/jimmunol.194.supp.195.3
https://doi.org/10.4049/jimmunol.194.supp.195.3
Publikováno v:
The Journal of Immunology. 190:63.26-63.26
Non-steroidal anti-inflammatory drugs (NSAIDs) for food-producing animals such as swine need to control systemic and local inflammatory responses. However, there are no NSAIDs approved to control inflammation in swine due to an absence of qualified m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38d8b4531110fcfc7793bc6599380875
https://doi.org/10.4049/jimmunol.190.supp.63.26
https://doi.org/10.4049/jimmunol.190.supp.63.26