Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Heidi Skrenta"'
Autor:
Christine M. Seroogy, Patricia Lovelace, C. Garrison Fathman, Edgar G. Engleman, Heidi Skrenta, Chan D Chung, Niroshana Anandasabapathy, Luis Soares
Publikováno v:
Nature Immunology. 5:45-54
The active ubiquitin E3 ligase GRAIL is crucial in the induction of CD4 T cell anergy. Here we show that GRAIL is associated with and regulated by two isoforms of the ubiquitin-specific protease otubain 1. In lethally irradiated mice reconstituted wi
Autor:
Marie A. Hollenhorst, Claire Holness, C. Garrison Fathman, Niroshana Anandasabapathy, Christine M. Seroogy, Gregory S. Ford, Violette Paragas, Luis Soares, Debra Bloom, Heidi Skrenta
Publikováno v:
Immunity. 18:535-547
T cell anergy may serve to limit autoreactive T cell responses. We examined early changes in gene expression after antigen-TCR signaling in the presence (activation) or absence (anergy) of B7 costimulation. Induced expression of GRAIL (gene related t
Publikováno v:
The Journal of Immunology. 164:3506-3511
Activated T lymphocytes modulate the level of many molecules on their cell surface, including cytokine receptors. This regulation of cytokine receptor expression affects the ability of T cells to respond to cytokines and thus influences the outcome o
Autor:
Niroshana, Anandasabapathy, Gregory S, Ford, Debra, Bloom, Claire, Holness, Violette, Paragas, Christine, Seroogy, Heidi, Skrenta, Marie, Hollenhorst, C Garrison, Fathman, Luis, Soares
Publikováno v:
Immunity. 18(4)
T cell anergy may serve to limit autoreactive T cell responses. We examined early changes in gene expression after antigen-TCR signaling in the presence (activation) or absence (anergy) of B7 costimulation. Induced expression of GRAIL (gene related t