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pro vyhledávání: '"Heidi Shira David"'
Autor:
Teresa Wei-sy Lee, Heidi Shira David, Amanda Kathryn Engstrom, Brandon Scott Carpenter, David John Katz
Publikováno v:
eLife, Vol 8 (2019)
In Caenorhabditis elegans, mutations in WDR-5 and other components of the COMPASS H3K4 methyltransferase complex extend lifespan and enable its inheritance. Here, we show that wdr-5 mutant longevity is itself a transgenerational trait that correspond
Externí odkaz:
https://doaj.org/article/7478ec49cc754fc6835d098dbd226e5c
Publikováno v:
eLife, Vol 8 (2019)
In Caenorhabditis elegans, mutations in WDR-5 and other components of the COMPASS H3K4 methyltransferase complex extend lifespan and enable its inheritance. Here, we show that wdr-5 mutant longevity is itself a transgenerational trait that correspond
During active transcription, the COMPASS complex methylates histone H3 at lysine 4 (H3K4me). In Caenorhabditis elegans, mutations in COMPASS subunits, including WDR-5, extend lifespan and enable the inheritance of increased lifespan in wild-type desc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bac970414ebfa9cccc3a96237a741e3
https://doi.org/10.1101/782136
https://doi.org/10.1101/782136