Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Heidi Schilter"'
Autor:
Alison Findlay, Craig Turner, Heidi Schilter, Mandar Deodhar, Wenbin Zhou, Lara Perryman, Jonathan Foot, Amna Zahoor, Yimin Yao, Ross Hamilton, Mary Brock, Christina Raso, Jessica Stolp, Marie Galati, Dieter Hamprecht, Brett Charlton, Wolfgang Jarolimek
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 11, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/c99b1b5618214a2193bedd33dab46b7d
Autor:
May Yw Wong, Sonia Saad, Muh Geot Wong, Stefanie Stangenberg, Wolfgang Jarolimek, Heidi Schilter, Amgad Zaky, Anthony Gill, Carol Pollock
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234617 (2020)
Semicarbazide-sensitive amine oxidase (SSAO) is an enzyme with a unique dual function in controlling inflammation as well as reactive oxygen species (ROS) generation. We have demonstrated benefit of SSAO inhibition in acute kidney fibrosis. However t
Externí odkaz:
https://doaj.org/article/ae193041ebcb4b28a9c4df1f41924916
Autor:
Zhou Wenbin, Mary Brock, Heidi Schilter, Mandar Deodhar, Lara Perryman, Jessica Stolp, Craig Ivan Turner, Dieter Hamprecht, Brett Charlton, Yimin Yao, Wolfgang Jarolimek, Christina Raso, Ross Hamilton, Jonathan Stuart Foot, Marie Galati, Alison D. Findlay, Amna Zahoor
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 11, Pp n/a-n/a (2021)
Clinical and Translational Medicine
Clinical and Translational Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3de0ce4b9cdc8a367fdf85379b88be7
https://doaj.org/article/c99b1b5618214a2193bedd33dab46b7d
https://doaj.org/article/c99b1b5618214a2193bedd33dab46b7d
Autor:
Nicole G. Hansbro, Mathew Suji Eapen, Heidi Schilter, Tamera J. Corte, Gang Liu, Mark A. Travis, Ashleigh M. Philp, Janette K. Burgess, Sukhwinder Singh Sohal, Christopher J. Burns, Philip M. Hansbro
Structural changes involving tissue remodelling and fibrosis are major features of many pulmonary diseases, including asthma, chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF). Abnormal deposition of extracellular m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951fb6874998585c639f060c32001676
https://hdl.handle.net/10453/154238
https://hdl.handle.net/10453/154238
Autor:
Amgad Zaky, Sonia Saad, Wolfgang Jarolimek, Stefanie Stangenberg, Muh Geot Wong, Carol A. Pollock, Anthony J. Gill, May Yw Wong, Heidi Schilter
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 6, p e0234617 (2020)
PLoS ONE, Vol 15, Iss 6, p e0234617 (2020)
Semicarbazide-sensitive amine oxidase (SSAO) is an enzyme with a unique dual function in controlling inflammation as well as reactive oxygen species (ROS) generation. We have demonstrated benefit of SSAO inhibition in acute kidney fibrosis. However t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de0c7e57b1ca865ab638c60dce1e6d2c
https://pubmed.ncbi.nlm.nih.gov/32555665
https://pubmed.ncbi.nlm.nih.gov/32555665
Autor:
Wolfgang Jarolimek, Andrew G. Jarnicki, Heidi Schilter, Jonathan Stuart Foot, Philip M. Hansbro, Craig Ivan Turner, Zhou Wenbin, Mandar Deodhar, Gang Liu, Alison D. Findlay, Alberto Buson
Publikováno v:
Journal of medicinal chemistry. 62(21)
Lysyl oxidase-like 2 (LOXL2) is a secreted enzyme that catalyzes the formation of cross-links in extracellular matrix proteins, namely, collagen and elastin, and is indicated in fibrotic diseases. Herein, we report the identification and subsequent o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75af825d7a51df8d8363f42172222091
https://pubmed.ncbi.nlm.nih.gov/31580073
https://pubmed.ncbi.nlm.nih.gov/31580073
Autor:
Ama-Tawiah Essilfie, Philip M. Hansbro, Andrew G. Jarnicki, Wolfgang Jarolimek, Wheeldon K, Jonathan S. Foot, Heidi Schilter, Gang Liu, Yow Tt
Publikováno v:
British Journal of Pharmacology. 173:3161-3175
Background and Purpose Chronic obstructive pulmonary disease (COPD) is a major cause of illness and death, often induced by cigarette smoking (CS). It is characterized by pulmonary inflammation and fibrosis that impairs lung function. Existing treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::442d19e4a77681e64fd9d714ecc43240
https://doi.org/10.1111/bph.13573
https://doi.org/10.1111/bph.13573
Autor:
Amna Zahoor, Craig Ivan Turner, Heidi Schilter, Greco Angelique Elsa, Joshua Moses, Tin T Yow, Wolfgang Jarolimek, Zhou Wenbin, Mandar Deodhar, Alberto Buson, Sarah Townsend, Lara Perryman, Benjamin S. Rayner, Jonathan Stuart Foot, Alison D. Findlay, Amar Joshi
Publikováno v:
Journal of Cellular and Molecular Medicine
Fibrosis is characterized by the excessive deposition of extracellular matrix and crosslinked proteins, in particular collagen and elastin, leading to tissue stiffening and disrupted organ function. Lysyl oxidases are key players during this process,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::245fc3c8e82e47bdc6eb220ffe538eb3
https://pubmed.ncbi.nlm.nih.gov/30536539
https://pubmed.ncbi.nlm.nih.gov/30536539
Autor:
Anthony J. Gill, Heidi Schilter, Stefanie Stangenberg, Amgad Zaky, Sonia Saad, Carol A. Pollock, Muh Geot Wong
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
Diabetic nephropathy is characterised by the excessive amount of extracellular matrix in glomeruli and tubulointerstitial space. Lysyl oxidase-like 2 (LOXL2) is elevated in renal fibrosis and known to play key roles in ECM stabilisation by facilitati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41baea139dffa0d58a7a1db63435430
https://doi.org/10.1038/s41598-018-27462-6
https://doi.org/10.1038/s41598-018-27462-6
Autor:
Anthony J. Gill, Sonia Saad, Jason Chen, May Yw Wong, Wolfgang Jarolimek, Jie Zhang, Heidi Schilter, Simon Gross, Carol A. Pollock, Muh Geot Wong
Publikováno v:
American Journal of Physiology-Renal Physiology. 307:F908-F916
Semicarbazide-sensitive amine oxidase (SSAO) is an enzyme known for its dual function in mediating inflammation and reactive oxygen species production. However, the role of SSAO inhibitors in limiting kidney fibrosis is unclear. We aimed to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83fd491557ef0a797d70237b3a756ec5
https://doi.org/10.1152/ajprenal.00698.2013
https://doi.org/10.1152/ajprenal.00698.2013