Trends and drivers of pharmaceutical expenditures from systemic anti-cancer therapy

Autor: Lars Børty, Rasmus F. Brøndum, Heidi S. Christensen, Charles Vesteghem, Marianne Severinsen, Søren P. Johnsen, Lars H. Ehlers, Ursula Falkmer, Laurids Ø. Poulsen, Martin Bøgsted

Publikováno v: Børty, L, Brøndum, R F, Christensen, H S, Vesteghem, C, Severinsen, M, Johnsen, S P, Ehlers, L H, Falkmer, U, Poulsen, L Ø & Bøgsted, M 2023, ' Trends and drivers of pharmaceutical expenditures from systemic anti-cancer therapy ', The European Journal of Health Economics, vol. 24, no. 6, pp. 853–865 . https://doi.org/10.1007/s10198-022-01515-0
Børty, L, Brøndum, R F, Christensen, H S, Vesteghem, C, Severinsen, M, Johnsen, S P, Ehlers, L H, Falkmer, U, Poulsen, L Ø & Bøgsted, M 2022, ' Trends and drivers of pharmaceutical expenditures from systemic anti-cancer therapy ', The European Journal of Health Economics . https://doi.org/10.1007/s10198-022-01515-0

Expenditures on medicine for systemic anti-cancer therapy (SACT) have seen large increases in recent years. The characterization of patients with high SACT costs is crucial to identify cost-driving factors, but little is known about the distribution

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https://vbn.aau.dk/da/publications/ededcc58-8609-4d99-a9d9-ad2915f51728

Inter- and intra-observer variability of computed tomography-based parenchymal- and ductal diameters in chronic pancreatitis:a multi-observer international study

Autor: Jens Borgbjerg, Emily Steinkohl, Søren S. Olesen, Fatih Akisik, Anne Bethke, Edita Bieliuniene, Heidi S. Christensen, Trond Engjom, Ingfrid S. Haldorsen, Nikolaos Kartalis, Maria V. Lisitskaya, Gintare Naujokaite, Srdan Novovic, Imanta Ozola-Zālīte, Anna E. Phillips, Jordan K. Swensson, Asbjørn M. Drewes, Jens B. Frøkjær

Publikováno v: Borgbjerg, J, Steinkohl, E, Olesen, S S, Akisik, F, Bethke, A, Bieliuniene, E, Christensen, H S, Engjom, T, Haldorsen, I S, Kartalis, N, Lisitskaya, M V, Naujokaite, G, Novovic, S, Ozola-Zālīte, I, Phillips, A E, Swensson, J K, Drewes, A M & Frøkjær, J B 2023, ' Inter-and intra-observer variability of computed tomography-based parenchymal-and ductal diameters in chronic pancreatitis : a multi-observer international study ', Abdominal Radiology, vol. 48, no. 1, pp. 306-317 . https://doi.org/10.1007/s00261-022-03667-2

Purpose: The need for incorporation of quantitative imaging biomarkers of pancreatic parenchymal and ductal structures has been highlighted in recent proposals for new scoring systems in chronic pancreatitis (CP). To quantify inter- and intra-observe

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https://vbn.aau.dk/da/publications/c1b11015-f429-4e14-98fb-69a92fa26d97

Pre-treatment serum vitamin D deficiency is associated with increased inflammatory biomarkers and short overall survival in patients with pancreatic cancer

Autor: Niels Henrik Hollander, Per Pfeiffer, Louise Skau Rasmussen, Stig E. Bojesen, Astrid Z. Johansen, Mette Karen Yilmaz, Laurids Østergaard Poulsen, Carsten Palnæs Hansen, Heidi S. Christensen, Benny V. Jensen, Martin Bøgsted, Inna Chen, Fahimeh Andersen, Jon Kroll Bjerregaard, Julia S. Johansen, Ursula Falkmer, Svend Erik Nielsen, Jane Preuss Hasselby

Publikováno v: Rasmussen, L S, Yilmaz, M K, Falkmer, U G, Poulsen, L Ø, Bøgsted, M, Christensen, H S, Bojesen, S E, Jensen, B V, Chen, I M, Johansen, A Z, Hansen, C P, Hasselby, J P, Holländer, N, Nielsen, S E, Andersen, F, Bjerregaard, J K, Pfeiffer, P & Johansen, J S 2021, ' Pre-treatment serum vitamin D deficiency is associated with increased inflammatory biomarkers and short overall survival in patients with pancreatic cancer ', European Journal of Cancer, vol. 144, pp. 72-80 . https://doi.org/10.1016/j.ejca.2020.10.038
Rasmussen, L S, Yilmaz, M K, Falkmer, U G, Poulsen, L, Bøgsted, M, Christensen, H S, Bojesen, S E, Jensen, B V, Chen, I M, Johansen, A Z, Hansen, C P, Hasselby, J P, Holländer, N, Nielsen, S E, Andersen, F, Bjerregaard, J K, Pfeiffer, P & Johansen, J S 2021, ' Pre-treatment serum vitamin D deficiency is associated with increased inflammatory biomarkers and short overall survival in patients with pancreatic cancer ', European Journal of Cancer, vol. 144, pp. 72-80 . https://doi.org/10.1016/j.ejca.2020.10.038

Background: Vitamin D deficiency and inflammation are associated with increased mortality. We investigated the relationship between pre-treatment serum vitamin D levels, inflammatory biomarkers (IL-6, YKL-40 and CRP) and overall survival (OS) in panc

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https://doi.org/10.1016/j.ejca.2020.10.038

Point Processes on Directed Linear Networks

Autor: Heidi S. Christensen, Jakob Gulddahl Rasmussen

Publikováno v: Rasmussen, J G & Christensen, H S 2021, ' Point Processes on Directed Linear Networks ', Methodology and Computing in Applied Probability, vol. 23, no. 2, pp. 647–667 . https://doi.org/10.1007/s11009-020-09777-y

In this paper we consider point processes specified on directed linear networks, i.e. linear networks with associated directions. We adapt the so-called conditional intensity function used for specifying point processes on the time line to the settin

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https://doi.org/10.1007/s11009-020-09777-y

Clinical features affecting efficacy of immune checkpoint inhibitors in pretreated patients with advanced NSCLC: a Danish nationwide real-world study

Autor: Mette T. Mouritzen, Karen F. Junker, Andreas Carus, Morten Ladekarl, Peter Meldgaard, Anders W. M. Nielsen, Anna Livbjerg, Jacob W. Larsen, Halla Skuladottir, Charlotte Kristiansen, Kim Wedervang, Tine Schytte, Karin H. Hansen, Anne-Cathrine Østby, Malene S. Frank, Jakob Lauritsen, Jens B. Sørensen, Seppo W. Langer, Gitte F. Persson, Jon L. Andersen, Pernille H. Homann, Emilie B. Kristensen, Lars B. Drivsholm, Martin Bøgsted, Heidi S. Christensen, Mette Pøhl, Birgitte Bjørnhart

Publikováno v: Mouritzen, M T, Junker, K F, Carus, A, Ladekarl, M, Meldgaard, P, Nielsen, A W M, Livbjerg, A, Larsen, J W, Skuladottir, H, Kristiansen, C, Wedervang, K, Schytte, T, Hansen, K H, Østby, A-C, Frank, M S, Lauritsen, J, Sørensen, J B, Langer, S W, Persson, G F, Andersen, J L, Homann, P H, Kristensen, E B, Drivsholm, L B, Bøgsted, M, Christensen, H S, Pøhl, M & Bjørnhart, B 2022, ' Clinical features affecting efficacy of immune checkpoint inhibitors in pretreated patients with advanced NSCLC: a Danish nationwide real-world study ', Acta Oncologica, vol. 61, no. 4, pp. 409-416 . https://doi.org/10.1080/0284186X.2021.2023213
Mouritzen, M T, Junker, K F, Carus, A, Ladekarl, M, Meldgaard, P, Nielsen, A W M, Livbjerg, A, Larsen, J W, Skuladottir, H, Kristiansen, C, Wedervang, K, Schytte, T, Hansen, K H, Østby, A-C, Frank, M S, Lauritsen, J, Sørensen, J B, Langer, S W, Persson, G F, Andersen, J L, Homann, P H, Kristensen, E B, Drivsholm, L B, Bøgsted, M, Christensen, H S, Pøhl, M & Bjørnhart, B 2022, ' Clinical features affecting efficacy of immune checkpoint inhibitors in pretreated patients with advanced NSCLC : a Danish nationwide real-world study ', Acta Oncologica, vol. 61, no. 4, pp. 409-416 . https://doi.org/10.1080/0284186X.2021.2023213
Mouritzen, M T, Junker, K F, Carus, A, Ladekarl, M, Meldgaard, P, Nielsen, A W M, Livbjerg, A, Larsen, J W, Skuladottir, H, Kristiansen, C, Wedervang, K, Schytte, T, Hansen, K H, Østby, A C, Frank, M S, Lauritsen, J, Sørensen, J B, Langer, S W, Persson, G F, Andersen, J L, Homann, P H, Kristensen, E B, Drivsholm, L B, Bøgsted, M, Christensen, H S, Pøhl, M & Bjørnhart, B 2022, ' Clinical features affecting efficacy of immune checkpoint inhibitors in pretreated patients with advanced NSCLC : a Danish nationwide real-world study ', Acta Oncologica, vol. 61, no. 4, pp. 409-416 . https://doi.org/10.1080/0284186X.2021.2023213
Mouritzen, M T, Junker, K F, Carus, A, Ladekarl, M, Meldgaard, P, Nielsen, A W M, Livbjerg, A, Larsen, J W, Skuladottir, H, Kristiansen, C, Wedervang, K, Schytte, T, Hansen, K H, Østby, A-C, Frank, M S, Lauritsen, J, Sørensen, J B, Langer, S W, Persson, G F, Andersen, J L, Homann, P H, Kristensen, E B, Drivsholm, L B, Bøgsted, M, Christensen, H S, Pøhl, M & Bjørnhart, B 2022, ' Clinical features affecting efficacy of immune checkpoint inhibitors in pretreated patients with advanced NSCLC : a Danish nationwide real-world study ', Acta oncologica (Stockholm, Sweden), vol. 61, no. 4, pp. 409-416 . https://doi.org/10.1080/0284186X.2021.2023213

BACKGROUND: Immune checkpoint inhibitors (ICIs) are implemented as standard treatment for patients with advanced non-small cell lung cancer (NSCLC) in first-line and subsequent-line treatment. However, certain subgroups such as patients with older ag

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https://vbn.aau.dk/da/publications/686eb154-1718-4f76-8653-85dceaffd10e