Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Heidi R. Kast-Woelbern"'
Autor:
Diana M. Shih, Heidi R. Kast-Woelbern, Jack Wong, Yu-Rong Xia, Peter A. Edwards, Aldons J. Lusis
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 2, Pp 384-392 (2006)
Paraoxonase-1 (PON1), an enzyme that metabolizes organophosphate insecticides, is secreted by the liver and transported in the blood complexed to HDL. In humans and mice, low plasma levels of PON1 have also been linked to the development of atheroscl
Externí odkaz:
https://doaj.org/article/9185cf015fe94d64abdeaa15f04fb047
Autor:
Andrew M. Anisfeld, Heidi R. Kast-Woelbern, Hans Lee, Yanqiao Zhang, Florence Y. Lee, Peter A. Edwards
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 3, Pp 458-468 (2005)
Three genes, fibrinogen-α (FBGα), -β, and -γ, encode proteins that make up the mature FBG protein complex. This complex is secreted from the liver and plays a key role in coagulation in response to vascular disruption. We identified all three FBG
Externí odkaz:
https://doaj.org/article/d308df5bda65440aa920c9eb7d2440fe
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 12, Pp 2037-2041 (2002)
Affymetrix microarray data and Northern blot assays demonstrated that phospholipid transfer protein (PL222222222216) was induced 6-fold when either murine or human macrophages were incubated in the presence of ligands for the liver X receptor (LXR) a
Externí odkaz:
https://doaj.org/article/d284822ada134e6cab5da80089928525
Autor:
Michael I. Dorrell, Amy L. Rausch, Ryan T. Botts, MaryAnn Alexander, Dawn M. Goral, Daniel J. Elson, Paul Thompson, Stephen A. Bravo, Charisa E. Gillette, Gabriel Villegas, Jacob R. Tremblay, Erik N. Siles, Bridget M. Fortin, Allison L. Hale, Haylie M. Everett, Eric Garcia, Troy L. Kurz, Heidi R. Kast-Woelbern, Connor A. Lowey, Caylor B. Booth, Alec M. Johnson, Michael Wheelock, Carley Coopwood, Sarah Giles, Jessica F. Wada, Jeffrey M. Snowbarger, Roujih Tadros, Jordan A. Silva, Jack C. Rusing, Kaitlyn J. Purington
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 6, p e0252233 (2021)
PLoS ONE, Vol 16, Iss 6, p e0252233 (2021)
Tumor angiogenesis is critical for the growth and progression of cancer. As such, angiostasis is a treatment modality for cancer with potential utility for multiple types of cancer and fewer side effects. However, clinical success of angiostatic mono
Autor:
Peter A. Edwards, Heidi R. Kast-Woelbern, Jenny Chang, Stacey A. Jones, Guizhen Luo, Florence Y. Lee, Michael C. Fishbein
Publikováno v:
Journal of Biological Chemistry. 280:31792-31800
Alpha-crystallins comprise 35% of soluble proteins in the ocular lens and possess chaperone-like functions. Furthermore, the alphaA subunit (alphaA-crystallin) of alpha crystallin is thought to be "lens-specific" as only very low levels of expression
Autor:
Mark D. Leibowitz, Anne Reifel-Miller, Mason E. Brooks, Rosemary Cesario, Louise Y. de Grandpre, Kay Klausing, Heidi R. Kast-Woelbern, Li Sun, Sharon L. Dana, Deborah L. Osburn
Publikováno v:
Journal of Biological Chemistry. 279:23908-23915
Insulin-induced gene 1 (INSIG-1) is a key regulator in the processing of the sterol regulatory element-binding proteins (SREBPs). We demonstrated that Insig-1 is regulated by peroxisome proliferator-activated receptor gamma (PPARgamma) providing a li
Autor:
Timothy M. Willson, Kevin Jon Williams, Heidi R. Kast-Woelbern, Stacey A. Jones, Peter A. Edwards, Andrew M. Anisfeld, Marie E. Meyer, Yanqiao Zhang
Publikováno v:
Journal of Biological Chemistry. 278:20420-20428
Syndecan-1 (SDC1), a transmembrane heparan sulfate proteoglycan that participates in the binding and internalization of extracellular ligands, was identified in a screen designed to isolate genes that are regulated by the farnesoid X-receptor (FXR, N
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 12, Pp 2037-2041 (2002)
Affymetrix microarray data and Northern blot assays demonstrated that phospholipid transfer protein (PL222222222216) was induced 6-fold when either murine or human macrophages were incubated in the presence of ligands for the liver X receptor (LXR) a
Autor:
Jack Wong, Heidi R. Kast-Woelbern, Diana M. Shih, Aldons J. Lusis, Yu-Rong Xia, Peter A. Edwards
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 2, Pp 384-392 (2006)
Paraoxonase-1 (PON1), an enzyme that metabolizes organophosphate insecticides, is secreted by the liver and transported in the blood complexed to HDL. In humans and mice, low plasma levels of PON1 have also been linked to the development of atheroscl
Autor:
Andrew M. Anisfeld, Yanqiao Zhang, Florence Y. Lee, Heidi R. Kast-Woelbern, Peter A. Edwards, Hans Lee
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 3, Pp 458-468 (2005)
Three genes, fibrinogen-alpha (FBGalpha), -beta, and -gamma, encode proteins that make up the mature FBG protein complex. This complex is secreted from the liver and plays a key role in coagulation in response to vascular disruption. We identified al