Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Heidi R, Culver"'
Autor:
Laura J. Macdougall, Heidi R. Culver, Christopher N. Bowman, Marissa E. Wechsler, Adam Broerman, Kristi S. Anseth, Evan H. Benke
Publikováno v:
ACS Biomaterials Science & Engineering. 7:4282-4292
Storage and transportation of protein therapeutics using refrigeration is a costly process; a reliable electrical supply is vital, expensive equipment is needed, and unique transportation is requir...
Publikováno v:
Polym Chem
An approach to efficient and scalable production of oligonucleotide-based gel networks is presented. Specifically, a new class of xenonucleic acid (XNA) synthesized through a scalable and efficient thiol–ene polymerization mechanism, “clickable
Autor:
Christopher N. Bowman, Jasmine Sinha, Benjamin D. Fairbanks, Christopher J. Calo, Heidi R. Culver, Tania R Prieto
Publikováno v:
Biomacromolecules. 21:4205-4211
Click nucleic acids (CNAs) are a new, low-cost class of xeno nucleic acid (XNA) oligonucleotides synthesized by an efficient and scalable thiol-ene polymerization. In this work, a thorough characterization of oligo(thymine) CNA-oligo(adenine) DNA ((d
Publikováno v:
Trends in Chemistry. 2:43-56
Beyond their central role in storing and transmitting genetic information, nucleic acids are renowned for their high-specificity, high-affinity hybridization. In the past several decades, scientists have become increasingly interested in emulating th
Autor:
Payton J Martinez, Stephanie J. Bryant, Alex J. Anderson, Jasmine Sinha, Tania R Prieto, Christopher N. Bowman, Heidi R. Culver
Publikováno v:
Chem Commun (Camb)
Enrichment of mRNA is a key step in a number of molecular biology techniques, particularly in the rapidly growing field of transcriptomics. Currently, mRNA is isolated using oligo(thymine) DNA (oligo(dT)) immobilized on solid supports, which binds to
Publikováno v:
ACS Applied Nano Materials. 2:7549-7558
A phosphatidylcholine-based cerasome (PC-cerasome) was prepared by a combination of a copper-catalyzed azide alkyne cyclo-addition (CuAAC) reaction and a sol–gel condensation process. In a 2 wt % u...
Publikováno v:
Angewandte Chemie International Edition. 61
An athermal approach to mRNA enrichment from total RNA using a self-immolative thioester linked nucleic acids (TENA) is described. Oligo(thymine) (oT) TENA has a six-atom spacing between bases which allowed TENA to selectively base-pair with polyaden
Autor:
Laura J, Macdougall, Marissa E, Wechsler, Heidi R, Culver, Evan H, Benke, Adam, Broerman, Christopher N, Bowman, Kristi S, Anseth
Publikováno v:
ACS Biomater Sci Eng
Storage and transportation of protein therapeutics using refrigeration is a costly process; a reliable electrical supply is vital, expensive equipment is needed, and unique transportation is required. Reducing the reliance on the cold chain would ena
Publikováno v:
Chemical communications (Cambridge, England). 56(35)
Efficient intracellular delivery of biomacromolecules such as proteins continues to remain a challenge despite its potential for medicine. In this work, we show that mScarlet, a non cytotoxic red fluorescent protein (RFP) conjugated to Click Nucleic
This chapter explores polymers that are capable of degrading to smaller components under physiologically relevant conditions or upon exposure to specific stimuli. Such polymers have been used in a wide range of biomaterials, spanning from sutures to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::585ae6f1def695ab746bef6f696068cc
https://doi.org/10.1016/b978-0-12-816137-1.00015-5
https://doi.org/10.1016/b978-0-12-816137-1.00015-5