Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Heidi Ott"'
Autor:
Christopher J. Molloy, Bruce E. Tomczuk, Danielle Lawrence, Christian Baumann, Heidi Ott, Shelley K. Ballentine, Jinsheng Chen, Mark J. Wall, Kenneth J. Wilson, Sanath K. Meegalla, Lisa Boczon, Edward J. Yurkow, Yanmin Chen, Carl Crysler, Lee Zeng, Carol F. Franks, Robert R. Donatelli, Margery A. Chaikin, Judith F. Baker, Zhao Zhou, Robert W. Tuman, Carl R. Illig, Dana L. Johnson, Carl L. Manthey
Supplementary Figure 1, Tables 1-4 from JNJ-28312141, a novel orally active colony-stimulating factor-1 receptor/FMS-related receptor tyrosine kinase-3 receptor tyrosine kinase inhibitor with potential utility in solid tumors, bone metastases, and ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb53737462ca7c21b088c7e98afca976
https://doi.org/10.1158/1535-7163.22485255.v1
https://doi.org/10.1158/1535-7163.22485255.v1
Autor:
Christopher J. Molloy, Bruce E. Tomczuk, Danielle Lawrence, Christian Baumann, Heidi Ott, Shelley K. Ballentine, Jinsheng Chen, Mark J. Wall, Kenneth J. Wilson, Sanath K. Meegalla, Lisa Boczon, Edward J. Yurkow, Yanmin Chen, Carl Crysler, Lee Zeng, Carol F. Franks, Robert R. Donatelli, Margery A. Chaikin, Judith F. Baker, Zhao Zhou, Robert W. Tuman, Carl R. Illig, Dana L. Johnson, Carl L. Manthey
There is increasing evidence that tumor-associated macrophages promote the malignancy of some cancers. Colony-stimulating factor-1 (CSF-1) is expressed by many tumors and is a growth factor for macrophages and mediates osteoclast differentiation. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da7c495ed76df00defda047352171a57
https://doi.org/10.1158/1535-7163.c.6531858.v1
https://doi.org/10.1158/1535-7163.c.6531858.v1
Publikováno v:
Journal of Applied Toxicology. 42:913-926
Frameworks for deriving occupational exposure limits (OELs) and OEL-analogue values (such as derived-no-effect levels [DNELs]) in various regulatory areas in the EU and at national level in Germany were analysed. Reasons for differences between frame
Nach der Haftentlassung stehen Menschen großen Herausforderungen gegenüber und es ist schwierig, in die Gesellschaft zurückzufinden. Umso wichtiger ist es, sie bereits am ersten Tag ihrer Inhaftierung auf ihre Entlassung aus dem Gefängnis vorzube
Autor:
Mehrdad Lotfi Choobbari, Jennifer Ferguson, Niko Van den Brande, Tim Smith, Tatevik Chalyan, Wendy Meulebroeck, Heidi Ottevaere
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract The combination of different polymers in the form of blended plastics has been used in the plastic industry for a long time. Nevertheless, analyses of microplastics (MPs) have been mainly limited to the study of particles made of single-type
Externí odkaz:
https://doaj.org/article/cd6d45eba58c4ed9acad05116b3ff9f5
Publikováno v:
JPhys Photonics, Vol 6, Iss 4, p 045020 (2024)
Design and fabrication of multilayer thin film coatings for photonics applications require careful consideration of various parameters such as layer thickness, refractive indices and number of stacks. A growing trend uses machine learning for efficie
Externí odkaz:
https://doaj.org/article/d1de574bbf324a17acebbb15364a64fa
Publikováno v:
JPhys Photonics, Vol 6, Iss 4, p 045002 (2024)
Given the global rise in antimicrobial resistance levels, there is an urgent need to obtain the minimal inhibitory concentration (MIC) of an antibiotic as early as possible. In this paper, we present the first test results of a light-based concept wh
Externí odkaz:
https://doaj.org/article/c8665c84790443e2a06ac07cb88e9f42
Autor:
Mehdi Feizpour, Qing Liu, Tom Van der Donck, Hugo Thienpont, Wendy Meulebroeck, Heidi Ottevaere
Publikováno v:
JPhys Photonics, Vol 6, Iss 2, p 025002 (2024)
Surface-enhanced Raman spectroscopy (SERS) is a powerful optical sensing technique used in various applications, including medicine, microbiology, and environmental analysis. Planar SERS substrates are of particular interest due to their ease of inte
Externí odkaz:
https://doaj.org/article/cab2b1e87a9040579ee4a4f32d158fd5
Autor:
Danielle Lawrence, Yanmin Chen, Mark J. Wall, Carl L. Manthey, Christopher J. Molloy, Edward J. Yurkow, Kenneth J. Wilson, Sanath K. Meegalla, Dana L. Johnson, Carol F. Franks, Bruce E. Tomczuk, Lee Zeng, Shelley K. Ballentine, Baumann Christian Andrew, Zhao Zhou, Judith Baker, Robert R. Donatelli, Lisa Boczon, Carl Crysler, Carl R. Illig, Heidi Ott, Jinsheng Chen, Tuman Robert W, Margery A. Chaikin
Publikováno v:
Molecular Cancer Therapeutics. 8:3151-3161
There is increasing evidence that tumor-associated macrophages promote the malignancy of some cancers. Colony-stimulating factor-1 (CSF-1) is expressed by many tumors and is a growth factor for macrophages and mediates osteoclast differentiation. Her
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:4861-4865
A series of 4-amino-6-piperazin-1-yl-pyrimidine-5-carbaldehyde oximes has been discovered and developed as potent FLT3 tyrosine kinase inhibitors. The series exhibited potent antiproliferative activity against both an FLT3 ITD-mutated human leukemic