Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Heidi N. Leblanc"'
Autor:
Hai Li, Andrew Luo, Steven J. Chapin, Shelley Erin Ackerman, Marcin Kowanetz, Michael N. Alonso, Po Y. Ho, Arthur Lee, Karla Henning, Samuel C. Kimmey, Benjamin Ackerman, Joshua D. Gregorio, Brian Safina, Vishnu C. Ramani, David Dornan, Lauren Y. Sheu, Jennifer Melrose, Cecelia Pearson, Richard P. Laura, Bruce H. Devens, Justin A. Kenkel, Edgar G. Engleman, Lisa Blum, David Y. Jackson, Heidi N. Leblanc, Joseph C. Gonzalez, Grant Yonehiro, Yaron Carmi, Felix J. Hartmann, Sean C. Bendall, Murray L. Nguyen, Angela Luo, Jason C. Paik
Publikováno v:
Nat Cancer
Innate pattern recognition receptor agonists, including Toll-like receptors (TLRs), alter the tumor microenvironment and prime adaptive antitumor immunity. However, TLR agonists present toxicities associated with widespread immune activation after sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436acc59b100dcb9f23295f5a324b4fb
https://europepmc.org/articles/PMC9012298/
https://europepmc.org/articles/PMC9012298/
Autor:
Paul Ponath, Vangipuram S. Rangan, Huadong Sun, Pina M. Cardarelli, Xi-Tao Wang, Sandra Cristea, Debbie Strachan, Bing Chen, Chin Pan, Julien Sage, Daniel Menezes, Heidi N. Leblanc, Kwon-Sik Park, Shrikant Deshpande, Miho Oyasu
Publikováno v:
Clinical Cancer Research. 24:5178-5189
Purpose: The ganglioside fucosyl-GM1 (FucGM1) is a tumor-associated antigen expressed in a large percentage of human small cell lung cancer (SCLC) tumors, but absent in most normal adult tissues, making it a promising target in immuno-oncology. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab164fe1d04b22996926f998a9bfa6e
https://doi.org/10.1158/1078-0432.ccr-18-0018
https://doi.org/10.1158/1078-0432.ccr-18-0018
Autor:
Marcin Kowanetz, Ding Wang, Dejan Juric, Drew W. Rasco, Shelley Erin Ackerman, Sudhir Manda, Leisha A. Emens, Bob T. Li, Yoon-Koo Kang, Lawrence E. Garbo, Edith A. Perez, Manish R. Sharma, Michael N. Alonso, Paula R. Pohlmann, Jasgit C. Sachdev, Amreen Husain, Mark D. Pegram, Glenn J. Hanna, Heidi N. Leblanc, Arielle L Heeke, Keun-Wook Lee, Ecaterina Ileana Dumbrava, Alexander I. Spira, Jeeyun Lee, David Dornan, Kathleen N. Moore, Richard D. Carvajal, Daniel V.T. Catenacci
Publikováno v:
Cancer Research. 81:CT218-CT218
Background: To date, anti-HER2 monoclonal antibodies are the only immune therapies approved for treating pts with HER2-over-expressing cancers. Intratumoral delivery of immunostimulatory adjuncts such as toll-like receptor (TLR) 7/8 agonists can acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce1faf87b6a736bd28f0895b016ae752
https://doi.org/10.1158/1538-7445.am2021-ct218
https://doi.org/10.1158/1538-7445.am2021-ct218
Autor:
Ariella Sasson, Stefan Kirov, Julie Carman, Aiqing He, Ashok Dongre, Mingyi Liu, Kathryn Vanderlaag, Xi-Tao Wang, Heidi N. Leblanc, Omar Jabado, Vishal Patel, Kandasamy Ravi, Sunil Kuppasani, Ji Gao
Publikováno v:
Cancer Research. 78:2707-2707
Background: Integrated analysis of multi-omic data is important in understanding oncogenesis, pathology, and drug mechanism of action. Formalin-fixed, paraffin-embedded (FFPE) tissues comprise the bulk of archival specimens in hospitals and clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::341443f28ae91f39c2ca32351ee4039f
https://doi.org/10.1158/1538-7445.am2018-2707
https://doi.org/10.1158/1538-7445.am2018-2707
Publikováno v:
Photosynthesis Research. 95:279-284
Rhodobacter capsulatus contains lhaA and pucC genes that have been implicated in light-harvesting complex 1 and 2 (LH1 and LH2) assembly. The proteins encoded by these genes, and homologues in other photosynthetic organisms, have been classified as t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c4c967d22a2bacd0fefe67a8e17504
https://doi.org/10.1007/s11120-007-9258-x
https://doi.org/10.1007/s11120-007-9258-x
Autor:
Mohan Srinivasan, R. Todd Bunch, Haichun Huang, Susan Wong, Heidi N. Leblanc, Michelle Kuhne, Kent B. Thudium, Minhua Han, Sujata Singh, Xi-Tao Wang, Yi Wu, Diann Blanset, Diane Feingersh, Neysa Garner, Changyu Wang, Alan J. Korman, Mark J. Selby, Candy Garcia
Publikováno v:
Cancer immunology research. 2(9)
The programmed death-1 (PD-1) receptor serves as an immunologic checkpoint, limiting bystander tissue damage and preventing the development of autoimmunity during inflammatory responses. PD-1 is expressed by activated T cells and downmodulates T-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec4afbbd327a9b5cf6c2e22093de84e
https://pubmed.ncbi.nlm.nih.gov/24872026
https://pubmed.ncbi.nlm.nih.gov/24872026
Publikováno v:
Chromosoma. 108:401-411
Faithful segregation of sister chromatids during cell division requires properly regulated cohesion between the sister centromeres. The sister chromatids are attached along their lengths, but particularly tightly in the centromeric regions. Therefore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4787fe7c220534096245d8b4555ee97a
https://doi.org/10.1007/s004120050392
https://doi.org/10.1007/s004120050392
Autor:
Pina M. Cardarelli, Allison Luo, Codrina Ancuta, Geoff Nichol, Andra Balanescu, Rodica Chirieac, Vira Tseluyko, Heidi N. Leblanc, Michael Yellin, Igor Paliienko, Li-An Xu, Semen Ter-Vartanian, Xiaolu Tao
Publikováno v:
Arthritis and rheumatism. 64(6)
Objective CXCL10 (also known as interferon-γ–inducible 10-kd protein [IP-10]) is a chemokine that potentially plays a role in the immunopathogenesis of rheumatoid arthritis (RA). We undertook this phase II study to evaluate the efficacy and safety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b70441d31d157e5156ed092e69a930
https://pubmed.ncbi.nlm.nih.gov/22147649
https://pubmed.ncbi.nlm.nih.gov/22147649