Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Heidi L.H. Malaby"'
Autor:
Jane B. Lian, Gary S. Stein, Janet L. Stein, Jason Stumpff, Heidi L.H. Malaby, Prachi N. Ghule, Coralee E. Tye, Kirsten M. Tracy
MANCR-depleted MDA-MB-231 cells exhibit a more normal-like expression of genes related to cell cycle processes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206252cb8a19beb6c782f0482ee450ee
https://doi.org/10.1158/1541-7786.22513581
https://doi.org/10.1158/1541-7786.22513581
Autor:
Jane B. Lian, Gary S. Stein, Janet L. Stein, Jason Stumpff, Heidi L.H. Malaby, Prachi N. Ghule, Coralee E. Tye, Kirsten M. Tracy
MANCR depletion does not affect timing of anaphase onset.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cacd35dfdfb58ba181f56f17bda3be3
https://doi.org/10.1158/1541-7786.22513578
https://doi.org/10.1158/1541-7786.22513578
Autor:
Jane B. Lian, Gary S. Stein, Janet L. Stein, Jason Stumpff, Heidi L.H. Malaby, Prachi N. Ghule, Coralee E. Tye, Kirsten M. Tracy
Robust ASO-mediated depletion of MANCR in MDA-MB-231 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8547cc261f2ca7114073c0ab1200be
https://doi.org/10.1158/1541-7786.22513587.v1
https://doi.org/10.1158/1541-7786.22513587.v1
Autor:
Jane B. Lian, Gary S. Stein, Janet L. Stein, Jason Stumpff, Heidi L.H. Malaby, Prachi N. Ghule, Coralee E. Tye, Kirsten M. Tracy
Live cell imaging of MANCR ASO_2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d40fabd7bbb3843877dc4a2a605ebee
https://doi.org/10.1158/1541-7786.22513563
https://doi.org/10.1158/1541-7786.22513563
Autor:
Jane B. Lian, Gary S. Stein, Janet L. Stein, Jason Stumpff, Heidi L.H. Malaby, Prachi N. Ghule, Coralee E. Tye, Kirsten M. Tracy
Live cell imaging of Control ASO.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::281c56259970051cf679a1046a79f95c
https://doi.org/10.1158/1541-7786.22513566.v1
https://doi.org/10.1158/1541-7786.22513566.v1
Autor:
Jane B. Lian, Gary S. Stein, Janet L. Stein, Jason Stumpff, Heidi L.H. Malaby, Prachi N. Ghule, Coralee E. Tye, Kirsten M. Tracy
Validation of expressed genes from RNA-seq.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4b9bcec86bd3192cb3e05fcbd4cc51
https://doi.org/10.1158/1541-7786.22513584
https://doi.org/10.1158/1541-7786.22513584
Autor:
Jane B. Lian, Gary S. Stein, Janet L. Stein, Jason Stumpff, Heidi L.H. Malaby, Prachi N. Ghule, Coralee E. Tye, Kirsten M. Tracy
Gene set enrichment analysis of genes differentially expressed between control and MANCR knock down cells, and MCF-10A and MDA-MB-231 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4608f0db8d39ee6dc96c01a93170ebbe
https://doi.org/10.1158/1541-7786.22513572
https://doi.org/10.1158/1541-7786.22513572
Publikováno v:
The Journal of Cell Biology
Kinesin-binding protein (KBP) is identified as a regulator of the kinesins KIF18A and KIF15 during mitosis. KBP buffers the activity of these motors to control chromosome alignment and spindle integrity in metaphase and prevent lagging chromosomes in
Autor:
Zuzana Storchova, Lisa-Marie Stautmeister, Kathrin Laue, Nicholas J. Lyons, Mariya Kazachkova, Todd R. Golub, Andrew Jones, Stefano Santaguida, Sara Vanessa Bernhard, Jason Stumpff, Helen Tang, Marica Rosaria Ippolito, James M. McFarland, Adam J. Bass, Rameen Beroukhim, Uri Ben-David, Yael Cohen-Sharir, Irena Bockaj, Ankur K. Nagaraja, Carolyn Marquis, Diana C.J. Spierings, Mai Abdusamad, Floris Foijer, Heidi L.H. Malaby, Johanna Zerbib, René Wardenaar
Publikováno v:
Nature, 590(7846). Nature Publishing Group
Nature
Nature
Selective targeting of aneuploid cells is an attractive strategy for cancer treatment(1). However, it is unclear whether aneuploidy generates any clinically relevant vulnerabilities in cancer cells. Here we mapped the aneuploidy landscapes of about 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632fb9544da6ff2088c466a916cf5a86
https://research.rug.nl/en/publications/6435240d-9c09-4249-b11f-a46eeb586ffb
https://research.rug.nl/en/publications/6435240d-9c09-4249-b11f-a46eeb586ffb
Autor:
Joseph E. Clayton, Lisa Wood, Carolyn Marquis, Heidi L.H. Malaby, Katelyn A. Queen, Sarah E. Vandal, Cindy L. Fonseca, Jason Stumpff
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Chromosomal instability (CIN) is a hallmark of tumor cells caused by changes in the dynamics and control of microtubules that compromise the mitotic spindle. Thus, CIN cells may respond differently than diploid cells to treatments that target mitotic