Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Heidi Hoard-Fruchey"'
Autor:
Dennean S. Lippner, Melissa O Rhoomes, Ki Ma, Heidi Hoard-Fruchey, Gary A. Rockwood, Diane M Hildenberger, Kelly A. Basi, Susan M. DeLeon, William R Cappuccio
Publikováno v:
Chemical Research in Toxicology. 34:1530-1541
Smoke inhalation from a structure fire is a common route of cyanide poisoning in the U.S. Cyanide inhibits cellular respiration, often leading to death. Its rapid distribution throughout the body can result in injuries to multiple organs, and cyanide
Autor:
Rebecca J Lewandowski, Matthew A. Hartog, Heidi Hoard-Fruchey, Christopher S Hofmann, Katherine Sherman, Jaclynn Andres, Alfred M. Sciuto, Ashley A Melber, Benjamin Wong, Cristin Rothwell, Justin Tressler
Publikováno v:
Chemical research in toxicology. 34(9)
Phosphine (PH3) is a highly toxic, corrosive, flammable, heavier-than-air gas that is a commonly used fumigant. When used as a fumigant, PH3 can be released from compressed gas tanks or produced from commercially available metal phosphide tablets. Al
Autor:
Jeffrey A. Koenig, Liana M. Matson, Robyn B. Lee-Stubbs, Heidi Hoard-Fruchey, Cherish E. Ardinger, Doug M. Cerasoli, Jessica Chandler, C. Lin. Cadieux, John H. McDonough, Tsung-Ming A. Shih, Erik A. Johnson
Publikováno v:
Toxicology. 410:10-15
Genetics likely play a role in various responses to nerve agent (NA) exposure, as genetic background plays an important role in behavioral, neurological, and physiological responses. This study uses different mouse strains to identify if mouse strain
Autor:
Bryan J. McCranor, Benjamin Wong, Laura Jennings, Michelle Racine, Vanessa E. DeLey Cox, Wing Y. Tuet, Aliyah Dukes, Matthew A. Hartog, Erin Pueblo, Lily Thompson, Justin Tressler, Samuel A. Pierce, Samuel Stone, Heidi Hoard-Fruchey
Publikováno v:
Ann N Y Acad Sci
Fluoroacetate (FA) is a tasteless, odorless, water-soluble metabolic poison with severe toxicological effects. Characterized in the mid-1900s, it has been used as a rodenticide but is comparably lethal to all mammals. Many countries have restricted i
Autor:
Heidi Hoard-Fruchey, Justin Tressler, Alfred M. Sciuto, Jaclynn Andres, Tracey A. Hamilton, Cristin Rothwell, Katherine Sherman, Rebecca J Lewandowski, Benjamin Wong, Jennifer Devorak
Publikováno v:
Inhalation Toxicology. 29:494-505
Phosphine (PH3) is a toxidrome-spanning chemical that is widely used as an insecticide and rodenticide. Exposure to PH3 causes a host of target organ and systemic effects, including oxidative stress, cardiopulmonary toxicity, seizure-like activity an
Autor:
Margaret E. Martens, Heidi Hoard-Fruchey, Michael W. Perkins, Benjamin J. Wong, Alfred M. Sciuto
Publikováno v:
Annals of the New York Academy of Sciences. 1374:41-51
Rodenticides and pesticides pose a significant threat not only to the environment but also directly to humans by way of accidental and/or intentional exposure. Metal phosphides, such as aluminum, magnesium, and zinc phosphides, have gained popularity
Autor:
Dana R. Anderson, Wesley W. Holmes, Danielle C. Paradiso, Devon Andres, Radharaman Ray, James F. Dillman, Betty Benton, Alfred M. Sciuto, Cristin Rothwell, Brian Keyser, Heidi Hoard-Fruchey
Publikováno v:
Toxicology Letters. 244:8-20
Toxic industrial chemicals are used throughout the world to produce everyday products such as household and commercial cleaners, disinfectants, pesticides, pharmaceuticals, plastics, paper, and fertilizers. These chemicals are produced, stored, and t
Autor:
Wesley W. Holmes, Eric W. Nealley, Lily Thompson, Matthew A. Hartog, Ian Bearden, Heidi Hoard-Fruchey, Ki Ma
Publikováno v:
The FASEB Journal. 34:1-1
Autor:
Wesley W. Holmes, Matthew A. Hartog, Ian Bearden, Ki Ma, Eric W. Nealley, Lily Thompson, Heidi Hoard-Fruchey
Publikováno v:
The FASEB Journal. 34:1-1
Publikováno v:
Toxicology mechanisms and methods. 27(1)
Therapeutic development against exposure to toxic gases is hindered by the lack of appropriate models to evaluate candidate compounds prior to animal efficacy studies. In this study, an in vitro, air-liquid interface exposure model has been tested to