Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Heidi Fiegl"'
Autor:
Ankur Chakravarthy, Ian Reddin, Stephen Henderson, Cindy Dong, Nerissa Kirkwood, Maxmilan Jeyakumar, Daniela Rothschild Rodriguez, Natalia Gonzalez Martinez, Jacqueline McDermott, Xiaoping Su, Nagayasau Egawa, Christina S. Fjeldbo, Vilde Eide Skingen, Heidi Lyng, Mari Kyllesø Halle, Camilla Krakstad, Afschin Soleiman, Susanne Sprung, Matt Lechner, Peter J. I. Ellis, Mark Wass, Martin Michaelis, Heidi Fiegl, Helga Salvesen, Gareth J. Thomas, John Doorbar, Kerry Chester, Andrew Feber, Tim R. Fenton
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Human papillomavirus (HPV) is a known cause of cervical cancer. Here, the authors perform a multi-omic analysis using published cervical squamous cell carcinoma cohorts from the USA, Europe, and SubSaharan Africa and identify two cervical squamous ce
Externí odkaz:
https://doaj.org/article/9a5c4607e718467ca9be497358a18ce0
Autor:
Aparna Gunda, Chetana Basavaraj, Chandra Prakash Serkad V, Manjula Adinarayan, Ramu Kolli, Mallikarjuna Siraganahalli Eshwaraiah, Cristina Saura, Fiorella Ruiz, Patricia Gomez, Vicente Peg, Jose Jimenez, Susanne Sprung, Heidi Fiegl, Christine Brunner, Daniel Egle, GS Bhattacharyya, Manjiri M Bakre
Publikováno v:
Breast, Vol 63, Iss , Pp 1-8 (2022)
CanAssist Breast (CAB), a prognostic test uses immunohistochemistry (IHC) approach coupled with artificial intelligence-based machine learning algorithm for prognosis of early-stage hormone-receptor positive, HER2/neu negative breast cancer patients.
Externí odkaz:
https://doaj.org/article/bf93f3ec223f418db3bb9ab9cf75700c
Autor:
Nicole Heinzl, Katarzyna Koziel, Elisabeth Maritschnegg, Astrid Berger, Elisabeth Pechriggl, Heidi Fiegl, Alain G. Zeimet, Christian Marth, Robert Zeillinger, Nicole Concin
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The tumor suppressor protein p53 is mutated in half of all cancers and has been described to form amyloid-like structures, commonly known from key proteins in neurodegenerative diseases. Still, the clinical relevance of p53 aggregates remains largely
Externí odkaz:
https://doaj.org/article/3ce52af3f7894bba962ddcab3b06bac9
Autor:
Katharina Leitner, Irina Tsibulak, Verena Wieser, Katharina Knoll, Daniel Reimer, Christian Marth, Heidi Fiegl, Alain G. Zeimet
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract SMARCA4 and EZH2 are two functional key players of their respective antagonizing chromatin remodeling complexes SWI/SNF and PRC2. EZH2 inhibitory drugs may abrogate pro-oncogenic features of PRC2 and turn the balance to cell differentiation
Externí odkaz:
https://doaj.org/article/c0f898d9b817455c806a36660ea6347a
Autor:
Tushar Tomar, Nicolette G. Alkema, Leroy Schreuder, Gert Jan Meersma, Tim de Meyer, Wim van Criekinge, Harry G. Klip, Heidi Fiegl, Els van Nieuwenhuysen, Ignace Vergote, Martin Widschwendter, Ed Schuuring, Ate G. J. van der Zee, Steven de Jong, G. Bea A. Wisman
Publikováno v:
BMC Medicine, Vol 15, Iss 1, Pp 1-16 (2017)
Abstract Background Despite an early response to platinum-based chemotherapy in advanced stage high-grade serous ovarian cancer (HGSOC), the majority of patients will relapse with drug-resistant disease. Aberrant epigenetic alterations like DNA methy
Externí odkaz:
https://doaj.org/article/a06eb7d5a96d40b0ba2f31f1bb438006
Autor:
Uwe Schirmer, Heidi Fiegl, Marco Pfeifer, Alain G. Zeimet, Elisabeth Müller-Holzner, Peter K. Bode, Verena Tischler, Peter Altevogt
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-3 (2018)
Following publication of the original article [1], we have been alerted to errors in Figs. 2 and 8. In Fig. 2B, the GAPDH loading control for Hec1A cells is shown twice in error (in Fig. 2B and Fig. 2C). In Fig. 8, in testis case 1 (first column) the
Externí odkaz:
https://doaj.org/article/af281d7e721840a6b17876bbcfe04196
Autor:
Lourdes Rocamora-Reverte, Selma Tuzlak, Laura von Raffay, Marcel Tisch, Heidi Fiegl, Mathias Drach, Holger M. Reichardt, Andreas Villunger, Denise Tischner, G. Jan Wiegers
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Activation of the immune system increases systemic adrenal-derived glucocorticoid (GC) levels which downregulate the immune response as part of a negative feedback loop. While CD4+ T cells are essential target cells affected by GC, it is not known wh
Externí odkaz:
https://doaj.org/article/1ff41dd18e2a4e848458c96ff01777d9
Autor:
Christine Degasper, Andrea Brunner, Natalie Sampson, Irina Tsibulak, Verena Wieser, Hannah Welponer, Christian Marth, Heidi Fiegl, Alain Gustave Zeimet
Publikováno v:
Tumor Biology, Vol 41 (2019)
The aim of this study was to explore the role of NOX4 in the biology of the normal endometrium and endometrial cancer. NOX4 plays a key role in other adenocarcinomas and has been implicated in the pathogenesis of diabetes and obesity, which are impor
Externí odkaz:
https://doaj.org/article/96f7056c81634b64881b87d2eb91e453
Autor:
Günther K. Bonn, Andreas Widschwendter, Irene Mutz-Dehbalaie, Georg Goebel, Rania Bakry, Abida Abudukadeer, Heidi Fiegl
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 7, Pp 8353-8363 (2012)
This study was designed to investigate the DNA-methylation status of E-cadherin (CDH1) and H-cadherin (CDH13) in serum samples of cervical cancer patients and control patients with no malignant diseases and to evaluate the clinical utility of these m
Externí odkaz:
https://doaj.org/article/1f9fb87da40648b2814afd97ed292aac
Autor:
Allison Jones, Andrew E Teschendorff, Quanxi Li, Jane D Hayward, Athilakshmi Kannan, Tim Mould, James West, Michal Zikan, David Cibula, Heidi Fiegl, Shih-Han Lee, Elisabeth Wik, Richard Hadwin, Rupali Arora, Charlotte Lemech, Henna Turunen, Päivi Pakarinen, Ian J Jacobs, Helga B Salvesen, Milan K Bagchi, Indrani C Bagchi, Martin Widschwendter
Publikováno v:
PLoS Medicine, Vol 10, Iss 11, p e1001551 (2013)
BackgroundEndometrial cancer incidence is continuing to rise in the wake of the current ageing and obesity epidemics. Much of the risk for endometrial cancer development is influenced by the environment and lifestyle. Accumulating evidence suggests t
Externí odkaz:
https://doaj.org/article/73703b4583b84fbbbd4a043f8172571e