Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Heidi E. Kloefkorn"'
Spinal cord injury (SCI) can induce dysfunction in a multitude of neural circuits including those that lead to impaired sleep, respiratory dysfunction and neuropathic pain. We used a lower thoracic rodent contusion SCI model - known to develop mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53738f8888c3a0c1c4d8b1ce2f20d6b4
https://doi.org/10.1101/2021.11.15.468636
https://doi.org/10.1101/2021.11.15.468636
Autor:
A Lakhani, Supriya Nagesh, James M. Rehg, Heidi E. Kloefkorn, Nigel P. Pedersen, Lauren M. Aiani, A Moss, Shawn Hochman, W. N. Goolsby
Publikováno v:
J Neurosci Methods
Study Objective Validate a novel method for sleep-wake staging in mice using noninvasive electric field (EF) sensors. Methods Mice were implanted with electroencephalogram (EEG) and electromyogram (EMG) electrodes and housed individually. Noninvasive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79118a821cba73bf7148f534cc41242f
https://pubmed.ncbi.nlm.nih.gov/32619585
https://pubmed.ncbi.nlm.nih.gov/32619585
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39140 (2012)
We utilized an in vitro adult mouse extensor digitorum longus (EDL) nerve-attached preparation to characterize the responses of muscle spindle afferents to ramp-and-hold stretch and sinusoidal vibratory stimuli. Responses were measured at both room (
Externí odkaz:
https://doaj.org/article/711c5b3d8bc045e6ac269dd82cdcd753
Autor:
Kyle D. Allen, Heidi E. Kloefkorn
Publikováno v:
Connective Tissue Research. 58:373-385
The importance of the medial meniscus to knee health is demonstrated by studies which show meniscus injuries significantly increase the likelihood of developing osteoarthritis (OA), and knee OA can be modeled in rodents using simulated meniscus injur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7635fb96b478c5e48b20911c93070bc9
https://doi.org/10.1080/03008207.2016.1251425
https://doi.org/10.1080/03008207.2016.1251425
Autor:
James M. Rehg, LM Aiani, W. N. Goolsby, A Moss, A Lakhani, Shawn Hochman, Supriya Nagesh, Nigel P. Pedersen, Heidi E. Kloefkorn
BackgroundRodent sleep scoring in principally reliant on electroencephalogram (EEG) and electromyogram (EMG), but this approach is invasive, can be expensive, and requires expertise and specialized equipment. Affordable, simple to use, and noninvasiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67a8fbb780e1b13e016b3216b1f4304
https://doi.org/10.1101/794552
https://doi.org/10.1101/794552
Autor:
Elisa J. Gonzalez-Rothi, Travis R. Pettengill, David D. Fuller, Sara M.F. Turner, Kristi A. Streeter, Heidi E. Kloefkorn, Kyle D. Allen
Publikováno v:
Annals of Biomedical Engineering. 45:711-725
While rodent gait analysis can quantify the behavioral consequences of disease, significant methodological differences exist between analysis platforms and little validation has been performed to understand or mitigate these sources of variance. By p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a648eb2b0245e2b2292997f3427ffc5
https://doi.org/10.1007/s10439-016-1717-0
https://doi.org/10.1007/s10439-016-1717-0
Publikováno v:
EMBC
Unobtrusive monitoring of physio-behavioral variables from animals can minimize variability in preclinical research and thereby maximize the potential for clinical translation. In this paper, we present the design, implementation, and validation of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a66aa6dae89c58a27f3fbf277c83708
https://pubmed.ncbi.nlm.nih.gov/30440699
https://pubmed.ncbi.nlm.nih.gov/30440699
Publikováno v:
Osteoarthritis and cartilage. 27(1)
Summary Objective In osteoarthritis (OA) models, histology is commonly used to evaluate the severity of joint damage. Unfortunately, semi-quantitative histological grading systems include some level of subjectivity, and quantitative grading systems c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246af26cbb8b9dfc1ba473672346a9dd
https://pubmed.ncbi.nlm.nih.gov/30287396
https://pubmed.ncbi.nlm.nih.gov/30287396
Autor:
Emily H. Lakes, Brittany Y. Jacobs, Heidi E. Kloefkorn, John K. Neubert, Eric L. Rohrs, Kyle D. Allen, Robert M. Caudle
Publikováno v:
Journal of Neuroscience Methods. 248:1-6
Detecting behaviors related to orofacial pain in rodent models often relies on subjective investigator grades or methods that place the animal in a stressful environment. In this study, an operant-based behavioral assay is presented for the assessmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee9e83aca0627377930b8c453f289498
https://doi.org/10.1016/j.jneumeth.2015.03.022
https://doi.org/10.1016/j.jneumeth.2015.03.022
Publikováno v:
Osteoarthritis and cartilage. 25(7)
Summary Objective Parallel measures of osteoarthritis (OA) across species can help evaluate OA models relative to humans. Toward this need, our group recently developed a magnetic nanoparticle-based technology, termed magnetic capture, to analyze bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb87d6cce80a7d1d0f7cd1092dee1e78
https://pubmed.ncbi.nlm.nih.gov/28137664
https://pubmed.ncbi.nlm.nih.gov/28137664