Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Heidi Budde"'
Autor:
Hans Georg Mannherz, Heidi Budde, Muhammad Jarkas, Roua Hassoun, Natalia Malek-Chudzik, Antonina J. Mazur, Jelena Skuljec, Refik Pul, Markus Napirei, Nazha Hamdani
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 2, Pp 151407- (2024)
We analyzed actin cytoskeleton alterations during NET extrusion by neutrophil-like dHL-60 cells and human neutrophils in the absence of DNase1 containing serum to avoid chromatin degradation and microfilament disassembly. NET-formation by dHL-60 cell
Externí odkaz:
https://doaj.org/article/54c354006106440fb8831ac2fa492eb0
Autor:
Saltanat Zhazykbayeva, Roua Hassoun, Melissa Herwig, Heidi Budde, Árpád Kovács, Hans Georg Mannherz, Ibrahim El-Battrawy, Attila Tóth, Wolfgang E. Schmidt, Andreas Mügge, Nazha Hamdani
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Heart failure with preserved ejection fraction (HFpEF) is a complex cardiovascular insufficiency syndrome presenting with an ejection fraction (EF) of greater than 50% along with different proinflammatory and metabolic co-morbidities. Despite previou
Externí odkaz:
https://doaj.org/article/7ec97b2fac2b4eff83a689c7e3e65407
Autor:
Kamilla Gömöri, Melissa Herwig, Heidi Budde, Roua Hassoun, Nusratul Mostafi, Saltanat Zhazykbayeva, Marcel Sieme, Suvasini Modi, Tamara Szabados, Judit Pipis, Nikolett Farkas‐Morvay, István Leprán, Gergely Ágoston, István Baczkó, Árpád Kovács, Andreas Mügge, Péter Ferdinandy, Anikó Görbe, Péter Bencsik, Nazha Hamdani
Publikováno v:
ESC Heart Failure, Vol 9, Iss 4, Pp 2585-2600 (2022)
Abstract Aims Volume overload (VO) induced hypertrophy is one of the hallmarks to the development of heart diseases. Understanding the compensatory mechanisms involved in this process might help preventing the disease progression. Methods and results
Externí odkaz:
https://doaj.org/article/5bc7f550d1d24f3da34c24ff5cc862dd
Current Understanding of Molecular Pathophysiology of Heart Failure With Preserved Ejection Fraction
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Heart Failure (HF) is the most common cause of hospitalization in the Western societies. HF is a heterogeneous and complex syndrome that may result from any dysfunction of systolic or diastolic capacity. Abnormal diastolic left ventricular function w
Externí odkaz:
https://doaj.org/article/66537945998149179a20eafc6329040b
Autor:
Kamilla Gömöri, Melissa Herwig, Roua Hassoun, Heidi Budde, Nusratul Mostafi, Simin Delalat, Suvasini Modi, Merima Begovic, Tamara Szabados, Judit Pipis, Nikolett Farkas-Morvay, István Leprán, Árpád Kovács, Andreas Mügge, Péter Ferdinandy, Anikó Görbe, Péter Bencsik, Nazha Hamdani
Publikováno v:
Antioxidants, Vol 11, Iss 11, p 2210 (2022)
Volume-induced hypertrophy is one of the risk factors for cardiac morbidity and mortality. In addition, mechanical and metabolic dysfunction, aging, and cellular redox balance are also contributing factors to the disease progression. In this study, w
Externí odkaz:
https://doaj.org/article/12d16e342b124b6cb9013c40cb2f47ae
Autor:
Diana Cimiotti, Setsuko Fujita-Becker, Desirée Möhner, Natalia Smolina, Heidi Budde, Aline Wies, Lisa Morgenstern, Alexandra Gudkova, Thomas Sejersen, Gunnar Sjöberg, Andreas Mügge, Marc M Nowaczyk, Peter Reusch, Gabriele Pfitzer, Robert Stehle, Rasmus R Schröder, Hans G Mannherz, Anna Kostareva, Kornelia Jaquet
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229227 (2020)
TNNI3 encoding cTnI, the inhibitory subunit of the troponin complex, is the main target for mutations leading to restrictive cardiomyopathy (RCM). Here we investigate two cTnI-R170G/W amino acid replacements, identified in infantile RCM patients, whi
Externí odkaz:
https://doaj.org/article/bb47d502141e46aba86a3a8e42223132
Autor:
Heidi Budde, Roua Hassoun, Melina Tangos, Saltanat Zhazykbayeva, Melissa Herwig, Marharyta Varatnitskaya, Marcel Sieme, Simin Delalat, Innas Sultana, Detmar Kolijn, Kamilla Gömöri, Muhammad Jarkas, Mária Lódi, Kornelia Jaquet, Árpád Kovács, Hans Georg Mannherz, Vasco Sequeira, Andreas Mügge, Lars I. Leichert, Samuel Sossalla, Nazha Hamdani
Publikováno v:
Antioxidants, Vol 10, Iss 7, p 1134 (2021)
Oxidative stress is defined as an imbalance between the antioxidant defense system and the production of reactive oxygen species (ROS). At low levels, ROS are involved in the regulation of redox signaling for cell protection. However, upon chronical
Externí odkaz:
https://doaj.org/article/5a64d6c759cd4774ad0e5804a10b5de2
Autor:
Árpád Kovács, Melissa Herwig, Heidi Budde, Simin Delalat, Detmar Kolijn, Beáta Bódi, Roua Hassoun, Melina Tangos, Saltanat Zhazykbayeva, Ágnes Balogh, Dániel Czuriga, Sophie Van Linthout, Carsten Tschöpe, Naranjan S. Dhalla, Andreas Mügge, Attila Tóth, Zoltán Papp, Judit Barta, Nazha Hamdani
Publikováno v:
Antioxidants, Vol 10, Iss 6, p 964 (2021)
Standard heart failure (HF) therapies have failed to improve cardiac function or survival in HF patients with right ventricular (RV) dysfunction suggesting a divergence in the molecular mechanisms of RV vs. left ventricular (LV) failure. Here we aime
Externí odkaz:
https://doaj.org/article/bbb35f8350a1408ca00e6991a1edb5fc
Autor:
Ilona Schirmer, Tippaporn Bualeong, Heidi Budde, Diana Cimiotti, Avinash Appukuttan, Nicole Klein, Philip Steinwascher, Peter Reusch, Andreas Mügge, Rainer Meyer, Yury Ladilov, Kornelia Jaquet
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192322 (2018)
In contrast to the membrane bound adenylyl cyclases, the soluble adenylyl cyclase (sAC) is activated by bicarbonate and divalent ions including calcium. sAC is located in the cytosol, nuclei and mitochondria of several tissues including cardiac muscl
Externí odkaz:
https://doaj.org/article/80392e8fec8e4fc8bd7bab4cdaac4169
Autor:
Melina Tangos, Heidi Budde, Detmar Kolijn, Marcel Sieme, Saltanat Zhazykbayeva, Mária Lódi, Melissa Herwig, Kamilla Gömöri, Roua Hassoun, Emma Louise Robinson, Toni Luise Meister, Kornelia Jaquet, Árpád Kovács, Julian Mustroph, Katja Evert, Nina Babel, Miklós Fagyas, Diana Lindner, Klaus Püschel, Dirk Westermann, Hans Georg Mannherz, Francesco Paneni, Stephanie Pfaender, Attila Tóth, Andreas Mügge, Samuel Sossalla, Nazha Hamdani
Publikováno v:
International Journal of Cardiology. 362:196-205
The respiratory illness triggered by severe acute respiratory syndrome virus-2 (SARS-CoV-2) is often particularly serious or fatal amongst patients with pre-existing heart conditions. Although the mechanisms underlying SARS-CoV-2-related cardiac dama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1c5fedfac8c42a97e0a93bb100b52c
https://doi.org/10.1016/j.ijcard.2022.05.055
https://doi.org/10.1016/j.ijcard.2022.05.055