Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Heidi A. Schoenfeld"'
Autor:
Salvatore Siena, Vasileios Askoxylakis, Glenn Dranoff, Marc R. Pelletier, Lang Ho Lee, Lori A. Iaconis, Sarah M. Choi, Heidi A. Schoenfeld, Kulandayan Subramanian, Ping C. Mahling, Susan E. Cellitti, Alex Cortez, Yasutoshi Kuboki, Jaffer A. Ajani, Alessio Amatu, Toshihiko Doi, Sae-Won Han, Filip Janku
Supplementary Data from Preclinical Characterization and Phase I Study of an Anti–HER2-TLR7 Immune-Stimulator Antibody Conjugate in Patients with HER2+ Malignancies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5f94745c1462cb05163a0a0fdf5af8
https://doi.org/10.1158/2326-6066.22545749.v1
https://doi.org/10.1158/2326-6066.22545749.v1
Autor:
Filip Janku, Sae-Won Han, Toshihiko Doi, Alessio Amatu, Jaffer A. Ajani, Yasutoshi Kuboki, Alex Cortez, Susan E. Cellitti, Ping C. Mahling, Kulandayan Subramanian, Heidi A. Schoenfeld, Sarah M. Choi, Lori A. Iaconis, Lang Ho Lee, Marc R. Pelletier, Glenn Dranoff, Vasileios Askoxylakis, Salvatore Siena
Publikováno v:
Cancer immunology research. 10(12)
Immune-stimulator antibody conjugates (ISAC) combining tumor-targeting monoclonal antibodies with immunostimulatory agents allow targeted delivery of immune activators into tumors. NJH395 is a novel, first-in-class ISAC comprising a Toll-like recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce115f22f26b50ae1f4dc8d430b3fd1e
https://pubmed.ncbi.nlm.nih.gov/36129967
https://pubmed.ncbi.nlm.nih.gov/36129967
Autor:
Randall J. Bateman, David Kagan, Keith Mansfield, Neeta Shenoy, Julie Douville, Tim West, Geoffrey G. Goodrich, Randy L. Webb, Marc DeCristofaro, Chiara Buono, Wei Zhou, Frederic Cumin, Chandrassegar Saravanan, Mary S. Holubasch, Philip B. Verghese, Heidi A. Schoenfeld
Publikováno v:
Toxicology and Applied Pharmacology. 323:53-65
Sacubitril/valsartan (LCZ696) is the first angiotensin receptor neprilysin inhibitor approved to reduce cardiovascular mortality and hospitalization in patients with heart failure with reduced ejection fraction. As neprilysin (NEP) is one of several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b41e7e4be08e50b60a23d954de4a52
Autor:
Heidi A. Schoenfeld, Peter Hoffmann, Wenkui Li, William Kluwe, Kapil Vashisht, Tsu-han Lin, Li Li, Julie Boisclair, Herbert A. Schmid
Publikováno v:
Toxicology and Applied Pharmacology. 286(3):224-233
The somatostatin analog pasireotide and the 11β-hydroxylase inhibitor osilodrostat (LCI699) reduce cortisol levels by distinct mechanisms of action. There exists a scientific rationale to investigate the clinical efficacy of these two agents in comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f175c32984df6b6ed6462c83abd46e2
Autor:
Nick Flavahan, Linda Longo, Pierre Moulin, Wei Zhou, Valerie Dubost, Pritam S. Sahota, Lori Martin, Robert H. Spaet, Serafino Pantano, Heidi A. Schoenfeld, Bryan Burkey, Dan Lapadula, Virendar K. Kaushik, Phil Bentley, Salah-Dine Chibout, Peter Hoffmann, Michael Hayes, Steve Busch
Publikováno v:
Toxicologic Pathology. 42:684-695
The purpose of this article is to characterize skin lesions in cynomolgus monkeys following vildagliptin (dipeptidyl peptidase-4 inhibitor) treatment. Oral vildagliptin administration caused dose-dependent and reversible blister formation, peeling an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f493e4b7ae077b0d9abea167df25abb
https://doi.org/10.1177/0192623313516828
https://doi.org/10.1177/0192623313516828
Publikováno v:
Journal of Occupational Therapy, Schools, & Early Intervention. 2:6-19
Purpose. The efficacy of occupational therapy and the need for evidence-based practice have become of importance to school-based occupational therapy practitioners. This action research study was designed to describe the degree to which teachers felt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f49d87edceebbf758dd871ab79f0ebc
https://doi.org/10.1080/19411240902719983
https://doi.org/10.1080/19411240902719983
Publikováno v:
Physical & Occupational Therapy In Pediatrics. 28:369-387
Children with emotional disturbance frequently have difficulty regulating their classroom behaviors. Many have co-occurrence of other disabilities, such as sensory processing problems, which compound difficulties in school participation. This explora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb66cb95fc037e1fefad30ea76c23066
https://doi.org/10.1080/01942630802307127
https://doi.org/10.1080/01942630802307127
Autor:
Heidi A. Schoenfeld, Sutchin R. Patel, Shawna L. Fleming, Reza J. Rasoulpour, Eun Ji Kwon, Kim Boekelheide, Kamin J. Johnson, Stephanie Thompson, Theresa Allio, Michelle Embree-Ku, Susan J. Hall
Publikováno v:
Annual Review of Pharmacology and Toxicology. 43:125-147
Now in its third decade of mechanistic investigation, testicular injury caused by 2,5-hexanedione (2,5-HD) exposure is a well-studied model with a rich database. The development of this model reflects the larger changes that have moved biology from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51bba25619fca9f98ebaed97e1f4f0f3
https://doi.org/10.1146/annurev.pharmtox.43.100901.135930
https://doi.org/10.1146/annurev.pharmtox.43.100901.135930
Publikováno v:
Toxicology Letters. 135:167-183
A symposium was held at the 41st annual meeting of the Society of Toxicology with presentations that emphasized novel molecular and cellular pathways that modulate the response to testicular toxicants. The first two presentations described cellular a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77a8122f754f64b9db5ca812a5543173
https://doi.org/10.1016/s0378-4274(02)00254-0
https://doi.org/10.1016/s0378-4274(02)00254-0
Publikováno v:
Biology of Reproduction. 64:1273-1282
Aging in the male human is accompanied by testicular atrophy, although relatively little is known about the mechanisms underlying germ cell loss. Testicular atrophy in the aged Brown Norway rat, an animal model for studies of aging in the human, has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d22d3a85a7e3a288a47ea58abbc66bec
https://doi.org/10.1095/biolreprod64.4.1273
https://doi.org/10.1095/biolreprod64.4.1273