Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Heidi A. Creed"'
Autor:
Justin G. McDermott, Bethany L. Goodlett, Heidi A. Creed, Shobana Navaneethabalakrishnan, Joseph M. Rutkowski, Brett M. Mitchell
Publikováno v:
Kidney & Blood Pressure Research, Vol 49, Iss 1, Pp 588-604 (2024)
Introduction: Hypertension (HTN) is a major cardiovascular disease that can cause and be worsened by renal damage and inflammation. We previously reported that renal lymphatic endothelial cells (LECs) increase in response to HTN and that augmenting l
Externí odkaz:
https://doaj.org/article/b3f207b75b96414ba56512348cd9022e
Autor:
Gaurav Baranwal, Heidi A. Creed, Laurence M. Black, Alexa Auger, Alexander M. Quach, Rahul Vegiraju, Han E. Eckenrode, Anupam Agarwal, Joseph M. Rutkowski
Publikováno v:
Physiological Reports, Vol 9, Iss 22, Pp n/a-n/a (2021)
Abstract Acute kidney injury (AKI) is a major cause of patient mortality and a major risk multiplier for the progression to chronic kidney disease (CKD). The mechanism of the AKI to CKD transition is complex but is likely mediated by the extent and l
Externí odkaz:
https://doaj.org/article/9df51e6e7a444e208764ce246f7ac69d
Autor:
Paola C. Rosas, MD, PhD, BSPharm, Chad M. Warren, MS, Heidi A. Creed, BS, Jerome P. Trzeciakowski, PhD, R. John Solaro, PhD, Carl W. Tong, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 7, Pp 817-830 (2019)
Summary: Cardiac myosin binding protein-C (cMyBP-C) phosphorylation prevents aging-related cardiac dysfunction. We tested this hypothesis by aging genetic mouse models of hypophosphorylated cMyBP-C, wild-type equivalent, and phosphorylated-mimetic cM
Externí odkaz:
https://doaj.org/article/3f0f466b8a174049852691b9fb177b8e
Publikováno v:
Lymphatic Research and Biology. 20:358-367
Background: Generalized lymphatic anomalies (GLA) are complex vessel malformations that can impair lymphatic function. Potential GLA complications include lipid-rich lymph in the thoracic space or peritoneal cavity, respectively chylothorax and chylo
Autor:
Gaurav Baranwal, Bethany L. Goodlett, Cristina M. Arenaz, Heidi A. Creed, Shobana Navaneethabalakrishnan, Joseph M. Rutkowski, Robert C. Alaniz, Brett M. Mitchell
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9192
Hypertension affects over a billion adults worldwide and is a major risk factor for cardiovascular disease. Studies have reported that the microbiota and its metabolites regulate hypertension pathophysiology. Recently, tryptophan metabolites have bee
Autor:
Anupam Agarwal, Joseph M. Rutkowski, Alexa Auger, Han E. Eckenrode, Heidi A. Creed, Laurence M. Black, Rahul Vegiraju, Gaurav Baranwal, Alexander M. Quach
Publikováno v:
Physiological Reports
Physiological Reports, Vol 9, Iss 22, Pp n/a-n/a (2021)
Physiological Reports, Vol 9, Iss 22, Pp n/a-n/a (2021)
Acute kidney injury (AKI) is a major cause of patient mortality and a major risk multiplier for the progression to chronic kidney disease (CKD). The mechanism of the AKI to CKD transition is complex but is likely mediated by the extent and length of
Autor:
Heidi A, Creed, Carl W, Tong
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2319
Mouse models are extensively studied and well-used to study cardiomyopathies due to the genetic relevance of this model organism and increasing need to identify therapeutic targets. Cardiac myofibril preparation for whole hearts has proved to be an i
Autor:
Jerome P. Trzeciakowski, R. John Solaro, Paola C Rosas, Heidi A. Creed, Chad M. Warren, Carl W. Tong
Publikováno v:
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 4, Iss 7, Pp 817-830 (2019)
JACC: Basic to Translational Science, Vol 4, Iss 7, Pp 817-830 (2019)
Visual Abstract
Highlights • With aging, phosphorylated-mimetic cMyBP-C mice exhibited better survival, better preservation of systolic and diastolic functions, and unchanging wall thickness compared with control mice. • Aged wild-type equiv
Highlights • With aging, phosphorylated-mimetic cMyBP-C mice exhibited better survival, better preservation of systolic and diastolic functions, and unchanging wall thickness compared with control mice. • Aged wild-type equiv
Publikováno v:
The FASEB Journal. 35
Autor:
Heidi A. Creed, Suman S. Vadlamani, Walter E. Cromer, Andrea J. Reyna, Wei Wang, Ranjeet M. Dongaonkar, Bradley D. Upchurch, David C. Zawieja, Napoleon C. Busbuso, Mary-Catherine C. Clark, Matt C. Smithhart, Joseph M. Rutkowski, Stephanie N. Blais, Gaurav Baranwal
Publikováno v:
Acta physiologica (Oxford, England). 232(4)
AIM Fluid and macromolecule transport from the interstitium into and through lymphatic vessels is necessary for tissue homeostasis. While lymphatic capillary structure suggests that passive, paracellular transport would be the predominant route of ma