Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Heidi A Tissenbaum"'
Autor:
Samuel F. Kingsley, Yonghak Seo, Alicia Wood, Khursheed A. Wani, Xavier Gonzalez, Javier Irazoqui, Steven E. Finkel, Heidi A. Tissenbaum
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Overconsumption of dietary sugar can lead to many negative health effects including the development of Type 2 diabetes, metabolic syndrome, cardiovascular disease, and neurodegenerative disorders. Recently, the human intestinal microbiota, s
Externí odkaz:
https://doaj.org/article/50dac4f2f55e49d0b343584612b76ecc
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/bd5cac9eb81a473aa2823686df09f1d6
Autor:
Sri Devi Narasimhan, Kelvin Yen, Ankita Bansal, Eun-Soo Kwon, Srivatsan Padmanabhan, Heidi A Tissenbaum
Publikováno v:
PLoS Genetics, Vol 7, Iss 4, p e1001377 (2011)
The insulin/IGF-1 signaling (IIS) pathway is a conserved regulator of longevity, development, and metabolism. In Caenorhabditis elegans IIS involves activation of DAF-2 (insulin/IGF-1 receptor tyrosine kinase), AGE-1 (PI 3-kinase), and additional dow
Externí odkaz:
https://doaj.org/article/1227eebd27cb497d906131cb24f84101
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
The nematode Caenorhabditis elegans has been employed as a model organism to study human obesity due to the conservation of the pathways that regulate energy metabolism. To assay for fat storage in C. elegans, a number of fat-soluble dyes have been e
Externí odkaz:
https://doaj.org/article/231490ea6b74439aa90f562f21ab407e
Autor:
Blanka Rogina, Heidi A. Tissenbaum
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Aging is linked to a time-associated decline in both cellular function and repair capacity leading to malfunction on an organismal level, increased frailty, higher incidence of diseases, and death. As the population grows older, there is a need to re
Externí odkaz:
https://doaj.org/article/69692244e6cb4d11aa810e6302cae833
Autor:
Heidi A. Tissenbaum
Publikováno v:
Nematodes as Model Organisms ISBN: 9781789248791
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfe50aeedf7c563ca6f7100e3cc0fb41
https://doi.org/10.1079/9781789248814.0002
https://doi.org/10.1079/9781789248814.0002
Autor:
Heidi A. Tissenbaum, Yong-Hak Seo, Steven E. Finkel, Samuel F. Kingsley, Krishna S. Ghanta, Calista Allen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Intestinal microbiota play an essential role in the health of a host organism. Here, we define how commensal Escherichia coli (E. coli) alters its host after long term exposure to glucose using a Caenorhabditis elegans-E. coli system where only the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07af6b3bec587c454c79cf8f20959e9a
https://doi.org/10.1038/s41598-021-85046-3
https://doi.org/10.1038/s41598-021-85046-3
Autor:
Yong-Hak Seo, Heidi A. Tissenbaum, Samuel F. Kingsley, Calista Allen, Steven E. Finkel, Krishna S. Ghanta
Intestinal microbiota play an essential role in the health of a host organism. Here, we define how commensal Escherichia coli (E. coli) alters its host after long term exposure to glucose using a C. elegans-E. coli system. Our data reveal that bacter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40694e7d93403e214b8057abf3b3c9ef
https://doi.org/10.1101/2020.09.13.295451
https://doi.org/10.1101/2020.09.13.295451
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(12)
Increased added sugar is contributing to a rise in aging-related diseases. Here, we use the nematode, Caenorhabditis elegans, which store sugar as both glycogen and trehalose. We demonstrate that by modifying sugar storage, we can prevent the harmful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c351c4fadfaa68a55035d5e37f01e985
https://pubmed.ncbi.nlm.nih.gov/29511104
https://pubmed.ncbi.nlm.nih.gov/29511104
Autor:
Samuel F. Kingsley, Heidi A. Tissenbaum, Yong-Hak Seo, Griffin Patrick Walker, Michelle A. Mondoux
Publikováno v:
Proceedings of the National Academy of Sciences. 115
As Western diets continue to include an ever-increasing amount of sugar, there has been a rise in obesity and type 2 diabetes. To avoid metabolic diseases, the body must maintain proper metabolism, even on a high-sugar diet. In both humans and Caenor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1f172570907e30e80c931b41232980b
https://doi.org/10.1073/pnas.1714178115
https://doi.org/10.1073/pnas.1714178115