Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Heidi, Wolfmeier"'
Autor:
Heidi Wolfmeier, Samuel J. T. Wardell, Leo T. Liu, Reza Falsafi, Annette Draeger, Eduard B. Babiychuk, Daniel Pletzer, Robert E. W. Hancock
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Engineered liposomes composed of the naturally occurring lipids sphingomyelin (Sm) and cholesterol (Ch) have been demonstrated to efficiently neutralize toxins secreted by Gram-positive bacteria such as Streptococcus pneumoniae and Staphylococcus aur
Externí odkaz:
https://doaj.org/article/840210bfc16444c586864df92061739c
Autor:
Daniel Pletzer, Travis M. Blimkie, Heidi Wolfmeier, Yicong Li, Arjun Baghela, Amy H. Y. Lee, Reza Falsafi, Robert E. W. Hancock
Publikováno v:
mSystems, Vol 5, Iss 4 (2020)
ABSTRACT The bacterial stringent stress response, mediated by the signaling molecule guanosine tetraphosphate, ppGpp, has recently gained attention as being important during normal cellular growth and as a potential new therapeutic target, which warr
Externí odkaz:
https://doaj.org/article/94197f6636d04bce954a708fe7e6bc0a
Autor:
Daniel Pletzer, Evelyn Sun, Caleb Ritchie, Lauren Wilkinson, Leo T Liu, Michael J Trimble, Heidi Wolfmeier, Travis M Blimkie, Robert E W Hancock
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008444 (2020)
Cystic fibrosis (CF) is a genetic disease that affects mucin-producing body organs such as the lungs. Characteristic of CF is the production of thick, viscous mucus, containing the glycoprotein mucin, that can lead to progressive airway obstruction.
Externí odkaz:
https://doaj.org/article/d88ada66a6684776984907b7e6f26fb8
Autor:
Heidi Wolfmeier, Sarah C. Mansour, Leo T. Liu, Daniel Pletzer, Annette Draeger, Eduard B. Babiychuk, Robert E.W. Hancock
Publikováno v:
EBioMedicine, Vol 33, Iss , Pp 211-217 (2018)
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA), typified by the pulse-field type USA300, is an emerging endemic pathogen that is spreading rapidly among healthy people. CA-MRSA causes skin and soft tissue infections, life-
Externí odkaz:
https://doaj.org/article/015e710ff6b84a8094608431c5de5ae3
Autor:
René Köffel, Heidi Wolfmeier, Yu Larpin, Hervé Besançon, Roman Schoenauer, Viktoria S. Babiychuk, Patrick Drücker, Thomas Pabst, Timothy J. Mitchell, Eduard B. Babiychuk, Annette Draeger
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Bacterial infectious diseases are a leading cause of death. Pore-forming toxins (PFTs) are important virulence factors of Gram-positive pathogens, which disrupt the plasma membrane of host cells and can lead to cell death. Yet, host defense and cell
Externí odkaz:
https://doaj.org/article/ab204a27906c4eb7b16198098641d220
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Microorganisms continuously monitor their surroundings and adaptively respond to environmental cues. One way to cope with various stress-related situations is through the activation of the stringent stress response pathway. In Pseudomonas aeruginosa
Externí odkaz:
https://doaj.org/article/1b22f77afad9427b9421672750e6fd77
Autor:
Heidi, Wolfmeier, Samuel J T, Wardell, Leo T, Liu, Reza, Falsafi, Annette, Draeger, Eduard B, Babiychuk, Daniel, Pletzer, Robert E W, Hancock
Publikováno v:
Frontiers in microbiology. 13
Engineered liposomes composed of the naturally occurring lipids sphingomyelin (Sm) and cholesterol (Ch) have been demonstrated to efficiently neutralize toxins secreted by Gram-positive bacteria such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62e147cb5c161053b39650453ad72a86
https://pubmed.ncbi.nlm.nih.gov/35369481
https://pubmed.ncbi.nlm.nih.gov/35369481
Publikováno v:
The British journal of ophthalmology.
BackgroundThe choroid is densely innervated by all parts of the autonomic nervous system and further harbours a network of local nerve cells, the intrinsic choroidal neurons (ICN). Their function in ocular control is currently unknown. While morpholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c68c45d6312f51efa8f9e03f6eb603b
https://pubmed.ncbi.nlm.nih.gov/34933896
https://pubmed.ncbi.nlm.nih.gov/34933896
Autor:
Alexander P Atanassoff, Heidi Wolfmeier, Roman Schoenauer, Andrea Hostettler, Avi Ring, Annette Draeger, Eduard B Babiychuk
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89743 (2014)
Pathogenic bacteria secrete pore-forming toxins that permeabilize the plasma membrane of host cells. Nucleated cells possess protective mechanisms that repair toxin-damaged plasmalemma. Currently two putative repair scenarios are debated: either the
Externí odkaz:
https://doaj.org/article/8beed59bec4244f78bc9e0a34ea23a3c
Autor:
Reza Falsafi, Heidi Wolfmeier, Yicong Li, Arjun Baghela, Daniel Pletzer, Travis M. Blimkie, Amy S. Lee, Robert E. W. Hancock
Publikováno v:
mSystems, Vol 5, Iss 4 (2020)
mSystems
mSystems, Vol 5, Iss 4, p e00495-20 (2020)
mSystems
mSystems, Vol 5, Iss 4, p e00495-20 (2020)
Microorganisms need to adapt rapidly to survive harsh environmental changes. Here, we showed the broad influence of the highly studied bacterial stringent stress response under nonstressful conditions that indicate its general physiological importanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27db5735b8efdf7749cd74918664ec63
https://journals.asm.org/doi/10.1128/mSystems.00495-20
https://journals.asm.org/doi/10.1128/mSystems.00495-20